PMID- 30501940 OWN - NLM STAT- MEDLINE DCOM- 20190212 LR - 20190215 IS - 1166-7087 (Print) IS - 1166-7087 (Linking) VI - 28 IP - 17 DP - 2018 Dec TI - [Antibiotic prophylaxis in urodynamics: Clinical practice guidelines using a formal consensus method]. PG - 943-952 LID - S1166-7087(18)30612-2 [pii] LID - 10.1016/j.purol.2018.10.001 [doi] AB - OBJECTIVE: The aim of this work was to issue clinical practice guidelines on antibiotic prophylaxis in urodynamics (urodynamic studies, UDS). MATERIALS AND METHODS: Clinical practice guidelines were provided using a formal consensus method. Guidelines proposals were drew up by a multidisciplinary experts group (pilot group = steering group), then rated by a panel of 12 experts (rating group) using a formal consensus method, and then peer reviewed by a reviewing/reading group of experts (different from the rating group). RESULTS: Urine (bacterial) culture with antimicrobial susceptibility testing is recommended for all patients before UDS (strong agreement). In patients with no neurologic disease, the risk factors for tract urinary infection (UTI) after UDS are age > 70 years, recurrent UTI, and post-void residual volume > 100ml. In patients with neurologic disease, the risk factors for UTI after UDS are recurrent UTI, vesicoureteral reflux, and intermicturition pressure > 40cmH(2)O. If the urine culture is negative before UDS and there is no risk factor for UTI, antibiotic prophylaxis is not recommended (Strong agreement). If the urine culture is negative before UDS, but there are one or more risk factors for UTI, antibiotic prophylaxis is optional. If antibiotic prophylaxis is initiated, a single oral dose (3g) of fosfomycin-tromethamine two hours before UDS is recommended (Strong agreement). If there is bacterial colonization on UCB before UDS, antibiotic therapy is optional (Undecided). If prescribed, it should be adapted to the antimicrobial susceptibility of the identified bacterium or bacteria, started the day before and stopped after UDS (except for fosfomycin-tromethamine: a single dose the day before UDS is necessary and sufficient) (Strong agreement). In the event of UTI before UDS, the UTI should be treated and UDS postponed (Strong agreement). The proposed recommendations should not be changed for patients with a hip or knee replacement (Strong agreement). No antibiotic prophylaxis of bacterial endocarditis is necessary, including in high-risk patients with valvular heart disease (Strong agreement). CONCLUSION: These new guidelines should help to harmonize clinical practice and limit exposure to antibiotics. LEVEL OF EVIDENCE: 4. CI - Copyright (c) 2018. Published by Elsevier Masson SAS. FAU - Egrot, C AU - Egrot C AD - Service d'urologie, universite Paris-7, hopital Bichat Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France. Electronic address: christophe.egrot@aphp.fr. FAU - Dinh, A AU - Dinh A AD - Unite de maladies infectieuses, UVSQ, hopital Raymond-Poincare, AP-HP, 92380 Garches, France. FAU - Amarenco, G AU - Amarenco G AD - GRC 01, groupe de recherche clinique en neuro-urologie (GREEN), Sorbonne universite, hopital Tenon, AP-HP, 75020 Paris, France. FAU - Bernard, L AU - Bernard L AD - Service de medecine interne et maladies infectieuses, centre hospitalier regional Bretonneau, 37000 Tours, France. FAU - Birgand, G AU - Birgand G AD - Centre de prevention des infections associees aux soins, CHU de Nantes, 5, rue du Pr-Boquien, 44000 Nantes, France. FAU - Bruyere, F AU - Bruyere F AD - Service d'urologie, centre hospitalier regional universitaire de Tours, 37000 Tours, France. FAU - Chartier-Kastler, E AU - Chartier-Kastler E AD - Medecine Sorbonne Universite, hopital universitaire de la Pitie-Salpetriere, 75013 Paris, France. FAU - Cosson, M AU - Cosson M AD - Laboratoire BioTIM, ecole centrale de Lille, universite de Lille, CHU de Lille, 59000 Lille, France. FAU - Deffieux, X AU - Deffieux X AD - Service de gynecologie obstetrique, universite Paris-Sud, hopital Antoine-Beclere, groupe hospitalier Sud, AP-HP, 92140 Clamart, France. FAU - Denys, P AU - Denys P AD - Service de neuro-urologie, hopital Raymond-Poincare, AP-HP, 92380 Garches, France. FAU - Etienne, M AU - Etienne M AD - Service de maladies infectieuses et tropicales, hopital Charles-Nicolle, CHU de Rouen, 76000 Rouen, France. FAU - Fatton, B AU - Fatton B AD - Unite d'urogynecologie, groupe hospitalier Caremeau, CHU de Nimes, 30029 Nimes, France. FAU - Fritel, X AU - Fritel X AD - Service de gynecologie-obstetrique, CHU de Poitiers, 86000 Poitiers, France. FAU - Game, X AU - Game X AD - Departement d'urologie, transplantation renale et andrologie, CHU Rangueil, TSA 50032, 31059 Toulouse, France. FAU - Lawrence, C AU - Lawrence C AD - Service microbiologie et hygiene, hopital Raymond-Poincare, AP-HP, 92380 Garches, France. FAU - Lenormand, L AU - Lenormand L AD - Service d'urologie, centre federatif de pelviperineologie, CHU de Nantes, place A.-Ricordeau, 44093 Nantes cedex 01, France. FAU - Lepelletier, D AU - Lepelletier D AD - Service bacteriologie et hygiene hospitaliere, CHU de Nantes, 44093 Nantes cedex 01, France. FAU - Lucet, J-C AU - Lucet JC AD - Service de bacteriologie, hygiene, virologie, parasitologie, hopital Bichat-Claude-Bernard, AP-HP, Paris, France. FAU - Marit Ducamp, E AU - Marit Ducamp E AD - Service de medecine physique et readaptation, urodynamique, clinique Saint-Augustin, 33200 Bordeaux, France. FAU - Pulcini, C AU - Pulcini C AD - Infectious Diseases Department, universite de Lorraine, APEMAC, CHRU de Nancy, 54000 Nancy, France. FAU - Robain, G AU - Robain G AD - Service de reeducation neurologique, hopital Rothschild, AP-HP, 75012 Paris, France. FAU - Senneville, E AU - Senneville E AD - Service universitaire des maladies infectieuses et du voyageur, centre hospitalier Gustave-Dron, CHRU de Lille, 59200 Tourcoing, France. FAU - de Seze, M AU - de Seze M AD - Service de medecine physique et readaptation, urodynamique, clinique Saint-Augustin, 33200 Bordeaux, France. FAU - Sotto, A AU - Sotto A AD - Service des maladies infectieuses et tropicales, CHU de Nimes, place du Professeur-Robert-Debre, 30029 Nimes cedex, France. FAU - Zahar, J-R AU - Zahar JR AD - Departement de microbiologie, hopital Avicenne, AP-HP, groupe hospitalier Paris-Seine-Saint-Denis, 93000 Bobigny, France; Unite de recherche Inserm 1137, IAME, universite Paris-13, 93000 Bobigny, France. FAU - Caron, F AU - Caron F AD - Service des maladies infectieuses, groupe de recherche sur l'adaptation microbienne (EA2656), universite de Rouen, CHU de Rouen, 76000 Rouen, France. FAU - Hermieu, J-F AU - Hermieu JF AD - Service d'urologie, universite Paris-7, hopital Bichat Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France. LA - fre PT - Journal Article PT - Practice Guideline PT - Review TT - Antibioprophylaxie et bilan urodynamique : recommandations de bonne pratique par consensus formalise. DEP - 20181127 PL - France TA - Prog Urol JT - Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie JID - 9307844 RN - 0 (Anti-Bacterial Agents) SB - IM MH - Aged MH - Anti-Bacterial Agents/*therapeutic use MH - Antibiotic Prophylaxis/*methods/*standards MH - Consensus MH - Expert Testimony MH - France MH - Humans MH - Urinary Tract Infections/diagnosis/*drug therapy/microbiology MH - Urodynamics/*drug effects OTO - NOTNLM OT - Antibioprophylaxie OT - Antibiotic prophylaxis OT - Bacteriuria OT - Bacteriurie OT - Bilan urodynamique OT - Guidelines OT - Infection urinaire OT - Infective risk OT - Recommandations OT - Risque infectieux OT - Urinary tract infection OT - Urodynamic studies EDAT- 2018/12/07 06:00 MHDA- 2019/02/13 06:00 CRDT- 2018/12/04 06:00 PHST- 2018/09/27 00:00 [received] PHST- 2018/10/08 00:00 [revised] PHST- 2018/10/11 00:00 [accepted] PHST- 2018/12/07 06:00 [pubmed] PHST- 2019/02/13 06:00 [medline] PHST- 2018/12/04 06:00 [entrez] AID - S1166-7087(18)30612-2 [pii] AID - 10.1016/j.purol.2018.10.001 [doi] PST - ppublish SO - Prog Urol. 2018 Dec;28(17):943-952. doi: 10.1016/j.purol.2018.10.001. Epub 2018 Nov 27.