PMID- 30503596
OWN - NLM
STAT- MEDLINE
DCOM- 20191126
LR  - 20191126
IS  - 1876-7605 (Electronic)
IS  - 1936-8798 (Linking)
VI  - 11
IP  - 24
DP  - 2018 Dec 24
TI  - Repeat Pulmonary Valve Replacement: Similar Intermediate-Term Outcomes With 
      Surgical and Transcatheter Procedures.
PG  - 2495-2503
LID - S1936-8798(18)31652-2 [pii]
LID - 10.1016/j.jcin.2018.07.042 [doi]
AB  - OBJECTIVES: This study compares 30-day, 1-year, and 3-year echocardiographic 
      findings and clinical outcomes of transcatheter pulmonary valve-in-valve 
      replacement (TPVR) and repeat surgical pulmonary valve replacement (SPVR). 
      BACKGROUND: In patients with adult congenital heart disease and previous 
      pulmonary valve replacement (PVR) who require redo PVR, it is unclear whether 
      TPVR or repeat SPVR is the preferred strategy. METHODS: We retrospectively 
      identified 66 patients (TPVR, n = 36; SPVR, n = 30) with bioprosthetic pulmonary 
      valves (PVs) who underwent either TPVR or repeat SPVR at Emory Healthcare from 
      January 2007 to August 2017. RESULTS: The TPVR cohort had fewer men and more 
      patients with baseline New York Heart Association (NYHA) functional class III or 
      IV. There was no difference in mortality, cardiovascular readmission, or 
      post-procedural PV reintervention at 30 days, 1 year, or 3 years. Post-procedural 
      echocardiographic findings showed no difference in mean PV gradients between the 
      TPVR and SPVR groups at 30 days, 1 year, or 3 years. In the TPVR cohort, there 
      was less right ventricular dysfunction at 30 days (2.9% vs. 46.7%; p < 0.01), 
      despite higher baseline NYHA functional class in the SPVR cohort. CONCLUSIONS: In 
      patients with bioprosthetic PV dysfunction who underwent either TPVR or SPVR, 
      there was no difference in mortality, cardiovascular readmission, or repeat PV 
      intervention at 30 days, 1 year, or 3 years. Additionally, TPVR and SPVR had 
      similar intermediate-term PV longevity, with no difference in PV gradients or 
      PVR. The TPVR cohort also had less right ventricular dysfunction at 30 days 
      despite a higher baseline NYHA functional classification. These intermediate-term 
      results suggest that TPVR may be an attractive alternative to SPVR in patients 
      with previous bioprosthetic surgical PVs.
CI  - Copyright (c) 2018 American College of Cardiology Foundation. Published by Elsevier 
      Inc. All rights reserved.
FAU - Caughron, Hope
AU  - Caughron H
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Kim, Dennis
AU  - Kim D
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia; 
      Division of Cardiology, Children's Healthcare of Atlanta, Atlanta, Georgia.
FAU - Kamioka, Norihiko
AU  - Kamioka N
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Lerakis, Stamatios
AU  - Lerakis S
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Yousef, Altayyeb
AU  - Yousef A
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Maini, Aneesha
AU  - Maini A
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Reginauld, Shawn
AU  - Reginauld S
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Sahu, Anurag
AU  - Sahu A
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Shashidharan, Subhadra
AU  - Shashidharan S
AD  - Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, 
      Georgia.
FAU - Jokhadar, Maan
AU  - Jokhadar M
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Rodriguez, Fred H 3rd
AU  - Rodriguez FH 3rd
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Book, Wendy M
AU  - Book WM
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - McConnell, Michael
AU  - McConnell M
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Block, Peter C
AU  - Block PC
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
FAU - Babaliaros, Vasilis
AU  - Babaliaros V
AD  - Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia. 
      Electronic address: vbabali@emory.edu.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20181128
PL  - United States
TA  - JACC Cardiovasc Interv
JT  - JACC. Cardiovascular interventions
JID - 101467004
SB  - IM
CIN - JACC Cardiovasc Interv. 2018 Dec 24;11(24):2504-2506. PMID: 30503597
MH  - Adult
MH  - Bioprosthesis
MH  - *Cardiac Catheterization/adverse effects/instrumentation/mortality
MH  - Echocardiography
MH  - Female
MH  - Georgia
MH  - Heart Valve Prosthesis
MH  - Heart Valve Prosthesis Implantation/adverse 
      effects/instrumentation/*methods/mortality
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Prosthesis Design
MH  - Prosthesis Failure
MH  - Pulmonary Valve/diagnostic imaging/physiopathology/*surgery
MH  - Recovery of Function
MH  - Reoperation
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
MH  - Ventricular Function, Right
MH  - Young Adult
OTO - NOTNLM
OT  - congenital
OT  - pulmonary valve replacement
OT  - repeat
OT  - transcatheter
OT  - valve-in-valve
EDAT- 2018/12/07 06:00
MHDA- 2019/11/27 06:00
CRDT- 2018/12/04 06:00
PHST- 2018/04/05 00:00 [received]
PHST- 2018/07/23 00:00 [revised]
PHST- 2018/07/25 00:00 [accepted]
PHST- 2018/12/07 06:00 [pubmed]
PHST- 2019/11/27 06:00 [medline]
PHST- 2018/12/04 06:00 [entrez]
AID - S1936-8798(18)31652-2 [pii]
AID - 10.1016/j.jcin.2018.07.042 [doi]
PST - ppublish
SO  - JACC Cardiovasc Interv. 2018 Dec 24;11(24):2495-2503. doi: 
      10.1016/j.jcin.2018.07.042. Epub 2018 Nov 28.