PMID- 30505819
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220330
IS  - 2287-8882 (Print)
IS  - 2287-903X (Electronic)
IS  - 2287-8882 (Linking)
VI  - 6
IP  - 4
DP  - 2018 Dec
TI  - Comparison of the delta neutrophil index with procalcitonin, erythrocyte 
      sedimentation rate, and C-reactive protein as predictors of sepsis in patients 
      with acute prostatitis.
PG  - 157-161
LID - 10.1016/j.prnil.2018.05.001 [doi]
AB  - BACKGROUND: We investigated the usefulness of inflammatory markers including the 
      delta neutrophil index (DNI), erythrocyte sedimentation rate, C-reactive protein, 
      and procalcitonin as early predictors of sepsis in patients with acute 
      prostatitis (AP). In addition, we evaluated the efficacy of intermittent 
      catheterization for the initial management of acute urinary retention (AUR) in 
      patients with AP. MATERIALS AND METHODS: All patients who presented to the 
      emergency department and were admitted to the urology department from January 
      2011 to December 2013 were retrospectively reviewed. The clinical features, 
      prostate-specific antigen levels, inflammatory marker levels, and urine and blood 
      culture results were obtained from medical records. Patients who underwent 
      urethrocystoscopy or prostate biopsy within 7 days were excluded. RESULTS: Of 132 
      patients (mean age, 64.8 years) in this cohort, 17 (12.9%) had sepsis and 22 
      (16.7%) had positive blood cultures. Escherichia coli was the most common isolate 
      in blood and urine cultures. In multivariate analysis, the DNI and 
      prostate-specific antigen were identified as predictors of sepsis. The DNI was a 
      significant prognostic factor for bacteremia. In patients with AP, procalcitonin 
      was not a significant predictor of sepsis. Of 19 patients with AUR, 10 needed 
      Foley catheterization because of refractory AUR. C-reactive protein was a 
      significant predictor of failure of the initial management of AUR. CONCLUSIONS: 
      The DNI is useful as a predictive factor for sepsis and bacteremia in patients 
      with AP. Without mandatory cystostomy, intermittent catheterization could be one 
      of the useful management options of AUR in patients with AP.
FAU - Ahn, Hyun Kyu
AU  - Ahn HK
AD  - Department of Urology, Yonsei University College of Medicine, Seoul, Korea.
FAU - Koo, Kyo Chul
AU  - Koo KC
AD  - Department of Urology, Yonsei University College of Medicine, Seoul, Korea.
FAU - Chung, Byung Ha
AU  - Chung BH
AD  - Department of Urology, Yonsei University College of Medicine, Seoul, Korea.
FAU - Lee, Kwang Suk
AU  - Lee KS
AD  - Department of Urology, Yonsei University College of Medicine, Seoul, Korea.
LA  - eng
PT  - Journal Article
DEP - 20180601
PL  - Korea (South)
TA  - Prostate Int
JT  - Prostate international
JID - 101605566
PMC - PMC6251943
OTO - NOTNLM
OT  - AP, acute prostatitis
OT  - AUR, acute urinary retention
OT  - Acute bacterial prostatitis
OT  - BPH, benign prostatic hyperplasia
OT  - Bacteremia
OT  - Biological markers
OT  - CRP, C-reactive protein
OT  - DNI, delta neutrophil index
OT  - ESR, erythrocyte sedimentation rate
OT  - Escherichia coli
OT  - IPSS, International Prostate Syndrome Score
OT  - PSA, prostate-specific antigen
OT  - SIRS, systemic inflammatory response syndrome
OT  - Sepsis
OT  - WBC, white blood cell
EDAT- 2018/12/07 06:00
MHDA- 2018/12/07 06:01
PMCR- 2018/06/01
CRDT- 2018/12/04 06:00
PHST- 2017/12/13 00:00 [received]
PHST- 2018/04/20 00:00 [revised]
PHST- 2018/05/25 00:00 [accepted]
PHST- 2018/12/04 06:00 [entrez]
PHST- 2018/12/07 06:00 [pubmed]
PHST- 2018/12/07 06:01 [medline]
PHST- 2018/06/01 00:00 [pmc-release]
AID - S2287-8882(17)30161-7 [pii]
AID - 10.1016/j.prnil.2018.05.001 [doi]
PST - ppublish
SO  - Prostate Int. 2018 Dec;6(4):157-161. doi: 10.1016/j.prnil.2018.05.001. Epub 2018 
      Jun 1.