PMID- 30515692
OWN - NLM
STAT- MEDLINE
DCOM- 20190318
LR  - 20200225
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 26
IP  - 4
DP  - 2019 Feb
TI  - Residue behavior and risk assessment of cymoxanil in grape under field conditions 
      and survey of market samples in Guangzhou.
PG  - 3465-3472
LID - 10.1007/s11356-018-3890-1 [doi]
AB  - A simple and fast method based on liquid chromatography-tandem mass spectrometry 
      (LC-MS/MS) was developed for cymoxanil residue analysis in grape. Sample 
      preparation based on solid-liquid extraction was optimized without using 
      adsorbent for purification. Recoveries were 79.8-109.5% with relative standard 
      deviations (RSDs) of 2.5-9.4% at fortified levels from 0.001 to 0.50 mg/kg. The 
      limit of detection (LOD) was 0.3 mug/kg. Field trials were conducted to explore 
      the dissipation and terminal residue behavior of cymoxanil in grape. Results 
      showed that the half-lives of cymoxanil were from 0.5 to 0.7 days. Terminal 
      residues were from below the limit of quantification (LOQ) to 0.363 mg/kg. 
      Dietary exposure risk assessment revealed that the risk quotients (RQs) were much 
      less than 1. It was concluded that cymoxanil in grape raised negligible concerns 
      to human health under field conditions. Sixty grape samples from Guangzhou market 
      were found to be free of cymoxanil. The proposed study would provide reference 
      for appropriate use of cymoxanil in grape planting in China.
FAU - Huang, Jianxiang
AU  - Huang J
AD  - Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural 
      Sciences, Guangzhou, 510640, China.
AD  - Key Laboratory of Testing and Evaluation for Agro-product Quality and Safety, 
      Ministry of Agriculture and Rural Affairs, People's Republic of China, Guangzhou, 
      510640, China.
AD  - Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou), 
      Ministry of Agriculture and Rural Affairs, People's Republic of China, Guangzhou, 
      510640, China.
FAU - Ye, Qian
AU  - Ye Q
AD  - Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural 
      Sciences, Guangzhou, 510640, China.
AD  - Key Laboratory of Testing and Evaluation for Agro-product Quality and Safety, 
      Ministry of Agriculture and Rural Affairs, People's Republic of China, Guangzhou, 
      510640, China.
AD  - Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou), 
      Ministry of Agriculture and Rural Affairs, People's Republic of China, Guangzhou, 
      510640, China.
FAU - Wan, Kai
AU  - Wan K
AD  - Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural 
      Sciences, Guangzhou, 510640, China.
AD  - Key Laboratory of Testing and Evaluation for Agro-product Quality and Safety, 
      Ministry of Agriculture and Rural Affairs, People's Republic of China, Guangzhou, 
      510640, China.
AD  - Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou), 
      Ministry of Agriculture and Rural Affairs, People's Republic of China, Guangzhou, 
      510640, China.
FAU - Wang, Fuhua
AU  - Wang F
AD  - Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural 
      Sciences, Guangzhou, 510640, China. wfhwqs@163.com.
AD  - Key Laboratory of Testing and Evaluation for Agro-product Quality and Safety, 
      Ministry of Agriculture and Rural Affairs, People's Republic of China, Guangzhou, 
      510640, China. wfhwqs@163.com.
AD  - Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou), 
      Ministry of Agriculture and Rural Affairs, People's Republic of China, Guangzhou, 
      510640, China. wfhwqs@163.com.
LA  - eng
GR  - 21305019/National Natural Science Foundation of China/
GR  - GJFP2014001, GJFP2015001 and GJFP2016002/National Program for Quality and Safety 
      Risk Assessment of Agricultural Products of China/
PT  - Journal Article
DEP - 20181204
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Acetamides)
RN  - 0 (Pesticide Residues)
RN  - 57966-95-7 (2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide)
SB  - IM
MH  - Acetamides/*analysis/toxicity
MH  - China
MH  - Chromatography, Liquid/methods
MH  - Dietary Exposure
MH  - Humans
MH  - Limit of Detection
MH  - Pesticide Residues/*analysis/toxicity
MH  - Risk Assessment
MH  - Surveys and Questionnaires
MH  - Tandem Mass Spectrometry/methods
MH  - Vitis/*chemistry
OTO - NOTNLM
OT  - Cymoxanil
OT  - Grape
OT  - Guangzhou
OT  - Residue
OT  - Risk assessment
OT  - Survey
EDAT- 2018/12/06 06:00
MHDA- 2019/03/19 06:00
CRDT- 2018/12/06 06:00
PHST- 2018/09/29 00:00 [received]
PHST- 2018/11/28 00:00 [accepted]
PHST- 2018/12/06 06:00 [pubmed]
PHST- 2019/03/19 06:00 [medline]
PHST- 2018/12/06 06:00 [entrez]
AID - 10.1007/s11356-018-3890-1 [pii]
AID - 10.1007/s11356-018-3890-1 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2019 Feb;26(4):3465-3472. doi: 
      10.1007/s11356-018-3890-1. Epub 2018 Dec 4.