PMID- 30519036
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220330
IS  - 1178-6930 (Print)
IS  - 1178-6930 (Electronic)
IS  - 1178-6930 (Linking)
VI  - 11
DP  - 2018
TI  - Matched-pair analysis of survival in the patients with T3 laryngeal squamous cell 
      carcinoma treated with supracricoid partial laryngectomy or total laryngectomy.
PG  - 7947-7953
LID - 10.2147/OTT.S175358 [doi]
AB  - BACKGROUND: The survival outcomes between supracricoid partial laryngectomy 
      (SCPL) and total laryngectomy (TL) were compared in the groups of matched-pair 
      patients with T3 laryngeal squamous cell carcinoma (LSCC). METHODS: Patients with 
      T3 LSCC were matched based on prognostic factors. The Kaplan-Meier curve and the 
      Cox proportional hazards model were used for analysis on survival. RESULTS: A 
      total of 212 patients with T3 LSCC were included after matching (106 underwent 
      SCPL and 106 underwent TL). Multivariable analysis showed no differences in 
      overall survival (hazard risk [HR]=1.15; 95% CI: 0.79-1.67; P=0.47), 
      disease-specific survival (HR=1.11; 95% CI: 0.69-1.80; P=0.66), and 
      recurrence-free survival (HR=1.07; 95% CI: 0.68-1.68; P=0.77) between the SCPL 
      group and TL group. CONCLUSION: SCPL provides reliable therapeutic outcomes and 
      can be used to avoid a TL surgery in some patients with advanced primary 
      laryngeal cancer.
FAU - Xia, Xin
AU  - Xia X
AD  - Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College 
      Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, 
      Beijing, China, xingming.chen@hotmail.com.
FAU - Zhu, Ying-Ying
AU  - Zhu YY
AD  - Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College 
      Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, 
      Beijing, China, xingming.chen@hotmail.com.
FAU - Diao, Wen-Wen
AU  - Diao WW
AD  - Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College 
      Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, 
      Beijing, China, xingming.chen@hotmail.com.
FAU - Zhu, Xiao-Li
AU  - Zhu XL
AD  - Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College 
      Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, 
      Beijing, China, xingming.chen@hotmail.com.
FAU - Shi, Xiao-Hua
AU  - Shi XH
AD  - Department of Pathology, Peking Union Medical College Hospital, Peking Union 
      Medical College and Chinese Academy of Medical Sciences, Beijing, China.
FAU - Li, Wu-Yi
AU  - Li WY
AD  - Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College 
      Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, 
      Beijing, China, xingming.chen@hotmail.com.
FAU - Gao, Zhi-Qiang
AU  - Gao ZQ
AD  - Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College 
      Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, 
      Beijing, China, xingming.chen@hotmail.com.
FAU - Li, Guo-Jun
AU  - Li GJ
AD  - Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College 
      Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, 
      Beijing, China, xingming.chen@hotmail.com.
FAU - Chen, Xing-Ming
AU  - Chen XM
AD  - Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College 
      Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, 
      Beijing, China, xingming.chen@hotmail.com.
LA  - eng
PT  - Journal Article
DEP - 20181109
PL  - New Zealand
TA  - Onco Targets Ther
JT  - OncoTargets and therapy
JID - 101514322
PMC - PMC6235336
OTO - NOTNLM
OT  - laryngeal neoplasms
OT  - laryngectomy
OT  - matched-pair analysis
OT  - squamous cell carcinoma
OT  - survival analysis
COIS- Disclosure The authors report no conflicts of interest in this work.
EDAT- 2018/12/07 06:00
MHDA- 2018/12/07 06:01
PMCR- 2018/11/09
CRDT- 2018/12/07 06:00
PHST- 2018/12/07 06:00 [entrez]
PHST- 2018/12/07 06:00 [pubmed]
PHST- 2018/12/07 06:01 [medline]
PHST- 2018/11/09 00:00 [pmc-release]
AID - ott-11-7947 [pii]
AID - 10.2147/OTT.S175358 [doi]
PST - epublish
SO  - Onco Targets Ther. 2018 Nov 9;11:7947-7953. doi: 10.2147/OTT.S175358. eCollection 
      2018.