PMID- 30524727
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220330
IS  - 0778-7367 (Print)
IS  - 2049-3258 (Electronic)
IS  - 0778-7367 (Linking)
VI  - 76
DP  - 2018
TI  - Implementation of human biomonitoring in the Dehcho region of the Northwest 
      Territories, Canada (2016-2017).
PG  - 73
LID - 10.1186/s13690-018-0318-9 [doi]
LID - 73
AB  - BACKGROUND: Human biomonitoring represents an important tool for health risk 
      assessment, supporting the characterization of contaminant exposure and nutrient 
      status. In communities where country foods (locally harvested foods: land 
      animals, fish, birds, plants) are integrated in the daily diet, as is the case in 
      remote northern regions where food security is a challenge, such foods can 
      potentially be a significant route of contaminant exposure. To assess this issue, 
      a biomonitoring project was implemented among Dene/Metis communities of the 
      Dehcho region of the Northwest Territories, Canada. METHODS: Participants 
      completed dietary surveys (i.e., a food frequency questionnaire and 24-h recall) 
      to estimate food consumption patterns as well as a Health Messages Survey to 
      evaluate the awareness and perception of contaminants and consumption notices. 
      Biological sampling of hair, urine and blood was conducted. Toxic metals (e.g., 
      mercury, lead, cadmium), essential metals (e.g., copper, nickel, zinc), fatty 
      acids, and persistent organic pollutants (POPs) were measured in samples. 
      RESULTS: The levels of contaminants in blood, hair and urine for the majority of 
      participants were below the available guidance values for mercury, cadmium, lead 
      and uranium. However, from the 279 participants, approximately 2% were invited to 
      provide follow up samples, mainly for elevated mercury level. Also, at the 
      population level, blood lead (GM: 11 mug/L) and blood cadmium (GM: 0.53 mug/L) were 
      slightly above the Canadian Health Measures Survey data. Therefore, although 
      country foods occasionally contain elevated levels of particular contaminants, 
      human exposures to these metals remained similar to those seen in the Canadian 
      general population. In addition, dietary data showed the importance and diversity 
      of country foods across participating communities, with the consumption of an 
      average of 5.1% of total calories from wild-harvested country foods. CONCLUSION: 
      This project completed in the Mackenzie Valley of the Northwest Territories fills 
      a data gap across other biomonitoring studies in Canada as it integrates 
      community results, will support stakeholders in the development of public health 
      strategies, and will inform environmental health issue prioritization.
FAU - Ratelle, Mylene
AU  - Ratelle M
AUID- ORCID: 0000-0002-5553-8612
AD  - 1School of Public Health and Health Systems, Faculty of Applied Health Sciences, 
      University of Waterloo, 200 University Ave W, Waterloo, ON Canada. ISNI: 0000 
      0000 8644 1405. GRID: grid.46078.3d
FAU - Skinner, Kelly
AU  - Skinner K
AD  - 1School of Public Health and Health Systems, Faculty of Applied Health Sciences, 
      University of Waterloo, 200 University Ave W, Waterloo, ON Canada. ISNI: 0000 
      0000 8644 1405. GRID: grid.46078.3d
FAU - Laird, Matthew J
AU  - Laird MJ
AD  - 1School of Public Health and Health Systems, Faculty of Applied Health Sciences, 
      University of Waterloo, 200 University Ave W, Waterloo, ON Canada. ISNI: 0000 
      0000 8644 1405. GRID: grid.46078.3d
FAU - Majowicz, Shannon
AU  - Majowicz S
AD  - 1School of Public Health and Health Systems, Faculty of Applied Health Sciences, 
      University of Waterloo, 200 University Ave W, Waterloo, ON Canada. ISNI: 0000 
      0000 8644 1405. GRID: grid.46078.3d
FAU - Brandow, Danielle
AU  - Brandow D
AD  - 1School of Public Health and Health Systems, Faculty of Applied Health Sciences, 
      University of Waterloo, 200 University Ave W, Waterloo, ON Canada. ISNI: 0000 
      0000 8644 1405. GRID: grid.46078.3d
FAU - Packull-McCormick, Sara
AU  - Packull-McCormick S
AD  - 1School of Public Health and Health Systems, Faculty of Applied Health Sciences, 
      University of Waterloo, 200 University Ave W, Waterloo, ON Canada. ISNI: 0000 
      0000 8644 1405. GRID: grid.46078.3d
FAU - Bouchard, Michele
AU  - Bouchard M
AD  - 2Faculty of Medicine, Universite de Montreal, 2900 Edouard-Montpetit, Montreal, 
      QC Canada. ISNI: 0000 0001 2292 3357. GRID: grid.14848.31
FAU - Dieme, Denis
AU  - Dieme D
AD  - 2Faculty of Medicine, Universite de Montreal, 2900 Edouard-Montpetit, Montreal, 
      QC Canada. ISNI: 0000 0001 2292 3357. GRID: grid.14848.31
FAU - Stark, Ken D
AU  - Stark KD
AD  - 1School of Public Health and Health Systems, Faculty of Applied Health Sciences, 
      University of Waterloo, 200 University Ave W, Waterloo, ON Canada. ISNI: 0000 
      0000 8644 1405. GRID: grid.46078.3d
FAU - Henao, Juan Jose Aristizabal
AU  - Henao JJA
AD  - 1School of Public Health and Health Systems, Faculty of Applied Health Sciences, 
      University of Waterloo, 200 University Ave W, Waterloo, ON Canada. ISNI: 0000 
      0000 8644 1405. GRID: grid.46078.3d
FAU - Hanning, Rhona
AU  - Hanning R
AD  - 1School of Public Health and Health Systems, Faculty of Applied Health Sciences, 
      University of Waterloo, 200 University Ave W, Waterloo, ON Canada. ISNI: 0000 
      0000 8644 1405. GRID: grid.46078.3d
FAU - Laird, Brian D
AU  - Laird BD
AD  - 1School of Public Health and Health Systems, Faculty of Applied Health Sciences, 
      University of Waterloo, 200 University Ave W, Waterloo, ON Canada. ISNI: 0000 
      0000 8644 1405. GRID: grid.46078.3d
LA  - eng
PT  - Journal Article
DEP - 20181203
PL  - England
TA  - Arch Public Health
JT  - Archives of public health = Archives belges de sante publique
JID - 9208826
PMC - PMC6276191
OTO - NOTNLM
OT  - Biomarker
OT  - Biomonitoring
OT  - Dene
OT  - Exposure
OT  - First nations
OT  - Metals
OT  - North
OT  - Risk assessment
OT  - Traditional foods
COIS- Participants provided a free consent. Ethics approval was obtained by the 
      University of Waterloo Research Ethics Committee (#20173, #20950), the Stanton 
      Territorial Health Authority for Human Research (29/12/2015), and the Aurora 
      Research Institute (#15560, #15775, #15966, #15977, #16021). Health Canada ethics 
      approval was also obtained regarding additional analysis of the biobanked samples 
      (REB 2016-0022).Not applicable.The authors declare that they have no competing 
      interests.Springer Nature remains neutral with regard to jurisdictional claims in 
      published maps and institutional affiliations.
EDAT- 2018/12/14 06:00
MHDA- 2018/12/14 06:01
PMCR- 2018/12/03
CRDT- 2018/12/08 06:00
PHST- 2018/09/05 00:00 [received]
PHST- 2018/10/24 00:00 [accepted]
PHST- 2018/12/08 06:00 [entrez]
PHST- 2018/12/14 06:00 [pubmed]
PHST- 2018/12/14 06:01 [medline]
PHST- 2018/12/03 00:00 [pmc-release]
AID - 318 [pii]
AID - 10.1186/s13690-018-0318-9 [doi]
PST - epublish
SO  - Arch Public Health. 2018 Dec 3;76:73. doi: 10.1186/s13690-018-0318-9. eCollection 
      2018.