PMID- 30526800
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221110
IS  - 1911-6470 (Print)
IS  - 1920-1214 (Electronic)
IS  - 1911-6470 (Linking)
VI  - 13
IP  - 8
DP  - 2019 Aug
TI  - Impact of LUTS on urine volume in stone formers The impact of lower urinary tract 
      symptomatology on urine volumes in stone formers.
PG  - 256-259
LID - 10.5489/cuaj.5530 [doi]
AB  - INTRODUCTION: We aimed to determine if there is a correlation between 
      International Prostate Symptom scores (IPSS) and 24-hour urine collection 
      volumes, as patients experiencing lower urinary tract symptoms (LUTS) may have 
      impaired ability to increase fluid intake for stone prevention. METHODS: We 
      conducted a single-centre, retrospective review was performed of stone-formers 
      presenting from 2014-2016. Inclusion criteria were completion of an IPSS 
      questionnaire and a 24-hour urine collection. Exclusion criteria included 
      symptomatic stone or urinary tract infection at time of IPSS completion, 
      inadequate 24-hour collection, or incomplete IPSS questionnaire. RESULTS: A total 
      of 131 patients met inclusion criteria. Stratification by IPSS severity into mild 
      (0-7), moderate (8-19), and severe (20-35) yielded groups of n=96, 28, and 7, 
      respectively. Linear regression modelling did not reveal a correlation between 
      IPSS score and volume (p=0.10). When compared to those with adequate urine 
      volumes (>2 L/day, n=65), low-volume patients (<1 L/day, n=10) had a 
      significantly higher total IPSS (11.7 vs. 6.1; p=0.036). These groups showed 
      significant differences in their responses to questions about incomplete emptying 
      (p=0.031), intermittency (p=0.011), and stranguria (p=0.0020), with higher scores 
      noted in the low urine output group. CONCLUSIONS: This study is the first to 
      examine the correlation between IPSS and 24-hour urine volume. Though our data 
      does not show a linear relationship between urine output and IPSS, those with 
      lower urine volumes appear to have worse self-reported voiding symptoms when 
      compared to those with adequate volumes (>2 L/day) for stone prevention. The 
      overall number of patients in our study is relatively small, which may account 
      for the lack of a relationship between IPSS and 24-hour urine volumes.
FAU - Hoy, Nathan Y
AU  - Hoy NY
AD  - Division of Urology, University of Alberta, Edmonton, AB, Canada.
FAU - Dean, Nick S
AU  - Dean NS
AD  - Division of Urology, University of Alberta, Edmonton, AB, Canada.
FAU - Wu, Jeremy
AU  - Wu J
AD  - Division of Urology, University of Alberta, Edmonton, AB, Canada.
FAU - Wollin, Timothy A
AU  - Wollin TA
AD  - Division of Urology, University of Alberta, Edmonton, AB, Canada.
FAU - De, Shubha K
AU  - De SK
AD  - Division of Urology, University of Alberta, Edmonton, AB, Canada.
LA  - eng
PT  - Journal Article
PL  - Canada
TA  - Can Urol Assoc J
JT  - Canadian Urological Association journal = Journal de l'Association des urologues 
      du Canada
JID - 101312644
PMC - PMC6737743
COIS- Competing interests: The authors report no competing personal or financial 
      interests related to this work.
EDAT- 2018/12/12 06:00
MHDA- 2018/12/12 06:01
PMCR- 2019/08/01
CRDT- 2018/12/12 06:00
PHST- 2018/12/12 06:00 [entrez]
PHST- 2018/12/12 06:00 [pubmed]
PHST- 2018/12/12 06:01 [medline]
PHST- 2019/08/01 00:00 [pmc-release]
AID - cuaj.5530 [pii]
AID - cuaj-8-256 [pii]
AID - 10.5489/cuaj.5530 [doi]
PST - ppublish
SO  - Can Urol Assoc J. 2019 Aug;13(8):256-259. doi: 10.5489/cuaj.5530.