PMID- 30529576 OWN - NLM STAT- MEDLINE DCOM- 20190212 LR - 20190215 IS - 1872-8227 (Electronic) IS - 0168-8227 (Linking) VI - 147 DP - 2019 Jan TI - A systematic review on costs and cost-effectiveness of screening and prevention of type 2 diabetes in women with prior gestational diabetes: Exploring uncharted territory. PG - 138-148 LID - S0168-8227(18)31026-X [pii] LID - 10.1016/j.diabres.2018.11.012 [doi] AB - AIMS: Women with gestational diabetes mellitus (GDM) are more likely to develop type 2 diabetes mellitus (T2DM) as compared to women with normoglycemic pregnancies. This study aims to explore the literature on cost(-effectiveness) of screening and prevention of T2DM in women with prior GDM. METHODS: Five databases were systematically searched, inclusion criteria were: (1) women with (prior) GDM; (2) post-partum screening or prevention of T2DM; and (3) health-economic evaluations. No year limits were applied. English, Dutch, French or German publications were included. Quality was assessed using the Consensus Health Economic Criteria checklist. RESULTS: Two cost-effectiveness analyses and two cost analyses were found. One study evaluated nine screening strategies. Three studies evaluated one prevention strategy each: intensive diet and behavioural modification; annual counseling; and an annual dietary consultation. Methodological quality was poor. Perspectives were unclear, time horizons were too short, and no incremental analyses were performed. CONCLUSION: An oral glucose tolerance test per three years leads to the lowest cost per case detected, and prevention is potentially cost-effective or cost-saving. More health economic evaluations are needed that compare all relevant alternatives, including 'doing nothing'. CI - Copyright (c) 2018 Elsevier B.V. All rights reserved. FAU - Werbrouck, Amber AU - Werbrouck A AD - Department of Public Health and Primary Care, Interuniversity Centre for Health Economics Research (I-CHER), Ghent University, De Pintelaan 185, 9000 Gent, Belgium; Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, O&N2 bus 521, Herestraat 49, 3000 Leuven, Belgium. Electronic address: amber.werbrouck@ugent.be. FAU - Schmidt, Masja AU - Schmidt M AD - Department of Public Health, Interuniversity Centre for Health Economics Research (I-CHER), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussel, Belgium. FAU - Putman, Koen AU - Putman K AD - Department of Public Health, Interuniversity Centre for Health Economics Research (I-CHER), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussel, Belgium. FAU - Benhalima, Katrien AU - Benhalima K AD - Department of Endocrinology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000 Leuven, Belgium. FAU - Verhaeghe, Nick AU - Verhaeghe N AD - Department of Public Health and Primary Care, Interuniversity Centre for Health Economics Research (I-CHER), Ghent University, De Pintelaan 185, 9000 Gent, Belgium; Department of Public Health, Interuniversity Centre for Health Economics Research (I-CHER), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussel, Belgium. FAU - Annemans, Lieven AU - Annemans L AD - Department of Public Health and Primary Care, Interuniversity Centre for Health Economics Research (I-CHER), Ghent University, De Pintelaan 185, 9000 Gent, Belgium. FAU - Simoens, Steven AU - Simoens S AD - Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, O&N2 bus 521, Herestraat 49, 3000 Leuven, Belgium. LA - eng PT - Journal Article PT - Systematic Review DEP - 20181207 PL - Ireland TA - Diabetes Res Clin Pract JT - Diabetes research and clinical practice JID - 8508335 SB - IM MH - Cost-Benefit Analysis/*methods MH - Diabetes Mellitus, Type 2/pathology/*prevention & control MH - Diabetes, Gestational/*economics/*prevention & control MH - Female MH - Humans MH - Mass Screening MH - Pregnancy OTO - NOTNLM OT - Gestational diabetes mellitus OT - Health economics OT - Prevention OT - Systematic review OT - Type 2 diabetes mellitus EDAT- 2018/12/12 06:00 MHDA- 2019/02/13 06:00 CRDT- 2018/12/12 06:00 PHST- 2018/07/05 00:00 [received] PHST- 2018/09/27 00:00 [revised] PHST- 2018/11/21 00:00 [accepted] PHST- 2018/12/12 06:00 [pubmed] PHST- 2019/02/13 06:00 [medline] PHST- 2018/12/12 06:00 [entrez] AID - S0168-8227(18)31026-X [pii] AID - 10.1016/j.diabres.2018.11.012 [doi] PST - ppublish SO - Diabetes Res Clin Pract. 2019 Jan;147:138-148. doi: 10.1016/j.diabres.2018.11.012. Epub 2018 Dec 7.