PMID- 30536604 OWN - NLM STAT- MEDLINE DCOM- 20200131 LR - 20200131 IS - 2042-6984 (Electronic) IS - 2042-6976 (Linking) VI - 9 IP - 4 DP - 2019 Apr TI - Wait times for endoscopic sinus surgery influence patient-reported outcome measures in patients with chronic rhinosinusitis who fulfill appropriateness criteria. PG - 396-401 LID - 10.1002/alr.22257 [doi] AB - BACKGROUND: Previous studies on the impact of wait times for endoscopic sinus surgery (ESS) in medically recalcitrant chronic rhinosinusitis (rCRS) have not examined its influence on the 5 distinct symptoms domains of the 22-item Sino-Nasal Outcome Test (SNOT-22), and have not applied evidence-based surgical indications. Our primary study objective was to investigate the impact of ESS wait times on postoperative SNOT-22 global and symptom domain scores in patients with rCRS deemed "appropriate" surgical candidates. METHODS: This was a retrospective analysis of adult patients with rCRS undergoing ESS, categorized as "appropriate" surgical candidates. Primary outcome measure was change in SNOT-22 global/symptom domain score (preoperative - 6-month postoperative). Correlational analyses were performed between wait time and change in SNOT-22 global and symptom domain scores. For significant negative correlations, the threshold wait time to generate a worsening in health-related quality-of-life (HRQoL) equivalent to the mean clinically important difference (MCID) was calculated. RESULTS: A total of 104 patients with a mean +/- standard deviation (SD) wait time of 310.8 +/- 155.9 days were analyzed. Postoperative SNOT-22 global and symptom domain scores significantly improved postoperatively. Wait time for ESS was negatively correlated with change in SNOT-22 global, rhinologic, extranasal rhinologic, and ear/facial domain scores (p < 0.05), and a wait time threshold of 287, 452, 421, and 381 days corresponded to a decrease equivalent to the MCID, respectively. CONCLUSION: We identified less improvement in HRQoL after ESS with increasing surgical wait time. Moreover, prolonged wait times may result in less improvement in disease-specific symptoms, but do not appear to worsen psychological or sleep dysfunction. CI - (c) 2018 ARS-AAOA, LLC. FAU - Yip, Jonathan AU - Yip J AD - Division of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada. FAU - Hao, Weibo AU - Hao W AD - Division of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada. FAU - Eskander, Antoine AU - Eskander A AD - Division of Head and Neck Oncology, Department of Otolaryngology-Head and Neck Surgery, Sunnybrook Health Sciences Centre and Michael Garron Hospital, University of Toronto, Toronto, ON, Canada. FAU - Lee, John M AU - Lee JM AD - Division of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada. LA - eng PT - Journal Article DEP - 20181210 PL - United States TA - Int Forum Allergy Rhinol JT - International forum of allergy & rhinology JID - 101550261 SB - IM MH - Adult MH - Chronic Disease MH - *Endoscopy MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Nasal Surgical Procedures MH - Patient Reported Outcome Measures MH - Quality of Life MH - Rhinitis/*surgery MH - Sinusitis/*surgery MH - *Waiting Lists OTO - NOTNLM OT - SNOT-22 OT - chronic rhinosinusitis OT - disease severity OT - endoscopic sinus surgery OT - patient-reported outcome measure OT - quality-of-life OT - sinus surgery EDAT- 2018/12/12 06:00 MHDA- 2020/02/01 06:00 CRDT- 2018/12/12 06:00 PHST- 2018/08/19 00:00 [received] PHST- 2018/10/16 00:00 [revised] PHST- 2018/11/13 00:00 [accepted] PHST- 2018/12/12 06:00 [pubmed] PHST- 2020/02/01 06:00 [medline] PHST- 2018/12/12 06:00 [entrez] AID - 10.1002/alr.22257 [doi] PST - ppublish SO - Int Forum Allergy Rhinol. 2019 Apr;9(4):396-401. doi: 10.1002/alr.22257. Epub 2018 Dec 10.