PMID- 30536660 OWN - NLM STAT- MEDLINE DCOM- 20200527 LR - 20200527 IS - 1097-0347 (Electronic) IS - 1043-3074 (Linking) VI - 41 IP - 1 DP - 2019 Jan TI - Sclerosis of the arytenoid cartilage and glottic carcinoma: A clinical-pathological study. PG - 72-78 LID - 10.1002/hed.25372 [doi] AB - BACKGROUND: Given the relevance of any tumor invasion of the arytenoid cartilage or crico-arytenoid unit to the planning open partial horizontal laryngectomy (OPHL) for laryngeal squamous cell carcinoma (LSCC), it is important to have a reliable radiological test to assess impairments of these structures. METHODS: We retrospectively compared the endoscopic, radiological, and pathological findings in patients with glottic LSCC who underwent OPHL. RESULTS: The endoscopic finding of a reduced (impaired or absent) vocal cord motility proved more sensitive, with better positive and negative predictive values, but less specific than the radiological finding of complete arytenoid sclerosis in detecting histologically assessable infiltration of the arytenoid cartilage. CONCLUSIONS: Endoscopy retains a key role in the preoperative workup for glottic LSCC. CT evidence of complete sclerosis of the arytenoid cartilage is related to a dangerous contiguity of the tumor to the cartilage. CI - (c) 2018 Wiley Periodicals, Inc. FAU - Lucioni, Marco AU - Lucioni M AD - Otolaryngology Unit, Vittorio Veneto Hospital, Treviso, Italy. FAU - Lionello, Marco AU - Lionello M AUID- ORCID: 0000-0002-2454-9618 AD - Otolaryngology Unit, Vittorio Veneto Hospital, Treviso, Italy. FAU - Machin, Piernicola AU - Machin P AD - Pathology Section, Conegliano Hospital, Treviso, Italy. FAU - Sovran, Federica AU - Sovran F AD - Radiology Unit, Vittorio Veneto Hospital, Treviso, Italy. FAU - Canal, Fabio AU - Canal F AD - Pathology Section, Conegliano Hospital, Treviso, Italy. FAU - Bertolin, Andy AU - Bertolin A AD - Otolaryngology Unit, Vittorio Veneto Hospital, Treviso, Italy. FAU - Rizzotto, Giuseppe AU - Rizzotto G AD - Otolaryngology Unit, Vittorio Veneto Hospital, Treviso, Italy. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20181207 PL - United States TA - Head Neck JT - Head & neck JID - 8902541 RN - 0 (Contrast Media) SB - IM MH - Arytenoid Cartilage/*diagnostic imaging/*pathology MH - Carcinoma, Squamous Cell/*complications/surgery MH - Contrast Media MH - Female MH - Humans MH - Laryngeal Neoplasms/*complications/surgery MH - Laryngectomy MH - Laryngoscopy MH - Male MH - Middle Aged MH - Predictive Value of Tests MH - Retrospective Studies MH - Sclerosis/*diagnosis MH - Sensitivity and Specificity MH - Tomography, X-Ray Computed OTO - NOTNLM OT - arytenoid OT - infiltration OT - motility OT - partial laryngectomy OT - sclerosis EDAT- 2018/12/12 06:00 MHDA- 2020/05/28 06:00 CRDT- 2018/12/12 06:00 PHST- 2017/12/08 00:00 [received] PHST- 2018/04/11 00:00 [revised] PHST- 2018/05/23 00:00 [accepted] PHST- 2018/12/12 06:00 [pubmed] PHST- 2020/05/28 06:00 [medline] PHST- 2018/12/12 06:00 [entrez] AID - 10.1002/hed.25372 [doi] PST - ppublish SO - Head Neck. 2019 Jan;41(1):72-78. doi: 10.1002/hed.25372. Epub 2018 Dec 7.