PMID- 30544481
OWN - NLM
STAT- MEDLINE
DCOM- 20181231
LR  - 20221005
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 49
DP  - 2018 Dec
TI  - Myocardial calcification found in Epstein-Barr viral myocarditis and 
      rhabdomyolysis: A case report.
PG  - e13582
LID - 10.1097/MD.0000000000013582 [doi]
LID - e13582
AB  - RATIONALE: The Epstein-Barr (EB) virus has rarely been reported as a cause of 
      fulminant myocarditis. To our knowledge, the present case is the first report on 
      myocardial calcification in EB viral myocarditis and rhabdomyolysis. PATIENT 
      CONCERNS: A 17-year-old man was admitted to the department with fever, chest 
      tightness, and tachypnea that had been present for 2 days. DIAGNOSES: The initial 
      investigation showed elevated liver enzyme levels, creatine kinase levels, 
      creatine kinase isoenzyme levels, and elevated serum myoglobin. Echocardiography 
      showed that left ventricular motion amplitude decreased. Test for immunoglobin M 
      and immunoglobin G antibodies against Epstein-Barr virus were positive. These 
      findings were consistent with fulminant myocarditis, cardiogenic shock, and 
      rhabdomyolysis. INTERVENTIONS: The patient was intensively treated with 
      venoarterial extracorporeal membrane oxygenation (VA-ECMO), continuous renal 
      replacement therapy (CRRT). OUTCOMES: Myocardial calcification was observed in 
      the left ventricle walls on CT examination 10 days after the admission. Four 
      months later, the patient is still alive and with adequate daily life. LESSONS: 
      This case indicates that this rare form of myocardial calcification may be 
      associated with EB viral infection and rhabdomyolysis.
FAU - Sui, Mingliang
AU  - Sui M
AD  - Department of Critical Care Medicine, Suzhou Kowloon Hospital, Shanghai Jiao Tong 
      University School of Medicine, Suzhou, China.
FAU - Tang, Weibing
AU  - Tang W
FAU - Wu, Changjiang
AU  - Wu C
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Adolescent
MH  - Calcinosis/*complications/diagnosis/therapy
MH  - Diagnosis, Differential
MH  - Epstein-Barr Virus Infections/*complications/diagnosis/therapy
MH  - Heart/diagnostic imaging
MH  - Humans
MH  - Male
MH  - Myocarditis/*complications/diagnosis/therapy
MH  - Rhabdomyolysis/*complications/diagnosis/therapy
MH  - Shock, Cardiogenic/*complications/diagnosis/therapy
PMC - PMC6310543
COIS- Competing interests The authors have no conflicts of interest to disclose.
EDAT- 2018/12/14 06:00
MHDA- 2019/01/01 06:00
PMCR- 2018/12/10
CRDT- 2018/12/15 06:00
PHST- 2018/12/15 06:00 [entrez]
PHST- 2018/12/14 06:00 [pubmed]
PHST- 2019/01/01 06:00 [medline]
PHST- 2018/12/10 00:00 [pmc-release]
AID - 00005792-201812070-00116 [pii]
AID - MD-D-18-05793 [pii]
AID - 10.1097/MD.0000000000013582 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Dec;97(49):e13582. doi: 10.1097/MD.0000000000013582.