PMID- 30556113 OWN - NLM STAT- MEDLINE DCOM- 20190528 LR - 20200225 IS - 1875-8312 (Electronic) IS - 1569-5794 (Linking) VI - 35 IP - 5 DP - 2019 May TI - Association between late gadolinium enhancement and global longitudinal strain in patients with rheumatic mitral stenosis. PG - 781-789 LID - 10.1007/s10554-018-1511-1 [doi] AB - The correlation between the extent of myocardial fibrosis and subclinical left ventricle (LV) systolic dysfunction in rheumatic mitral stenosis (MS) has not been widely studied. We sought to evaluate the correlation between the extent of LV myocardial fibrosis quantified by late gadolinium enhancement (LGE) using cardiac magnetic resonance (CMR) and global longitudinal strain (GLS) by speckle tracking echocardiography (STE) in patients with rheumatic MS. We prospectively evaluated 36 consecutive rheumatic MS patients who were planning to undergo mitral valve surgery. Then we evaluate the correlation between the extent of LV myocardial fibrosis quantified by LGE CMR and the systolic LV function by GLS using STE. Thirty-six patients with mean age of 45.7 +/- 9.9 years old, showed mean LGE was 4.9 +/- 2.7%. The mean LV ejection fraction (EF) measured by CMR was 50 +/- 10.8%, and the mean LV GLS was 13.5 +/- 3.9%. There was a moderate correlation between GLS and LGE (r - 0.432, p = 0.009). There were no correlations between GLS with mitral valve area (MVA) with r 0.149, p = 0.385, mean mitral valve gradient (MVG) with r -0.078, p = 0.653, and LVEF (r 0.299, p = 0.076). There was a moderate correlation between LGE and GLS in patients with rheumatic MS. FAU - Soesanto, Amiliana M AU - Soesanto AM AD - Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia / National Cardiovascular Center Harapan Kita, Jakarta, Indonesia. amiliana14@gmail.com. FAU - Desandri, Dwita Rian AU - Desandri DR AD - Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia / National Cardiovascular Center Harapan Kita, Jakarta, Indonesia. FAU - Haykal, Teuku Muhammad AU - Haykal TM AD - Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia / National Cardiovascular Center Harapan Kita, Jakarta, Indonesia. FAU - Kasim, Manoefris AU - Kasim M AD - Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia / National Cardiovascular Center Harapan Kita, Jakarta, Indonesia. LA - eng PT - Journal Article DEP - 20181217 PL - United States TA - Int J Cardiovasc Imaging JT - The international journal of cardiovascular imaging JID - 100969716 RN - 0 (Contrast Media) RN - AU0V1LM3JT (Gadolinium) SB - IM MH - Adult MH - Contrast Media/*administration & dosage MH - Female MH - Fibrosis MH - Gadolinium/*administration & dosage MH - Humans MH - *Magnetic Resonance Imaging MH - Male MH - Middle Aged MH - Mitral Valve/*diagnostic imaging/physiopathology MH - Mitral Valve Stenosis/*diagnostic imaging/pathology/physiopathology MH - Myocardium/pathology MH - Predictive Value of Tests MH - Prognosis MH - Prospective Studies MH - Rheumatic Heart Disease/*diagnostic imaging/pathology/physiopathology MH - Ventricular Dysfunction, Left/*diagnostic imaging/pathology/physiopathology MH - Ventricular Function, Left MH - Ventricular Remodeling OTO - NOTNLM OT - Cardiac magnetic resonance OT - Global longitudinal strain OT - Late gadolinium enhancement OT - Myocardial fibrosis OT - Rheumatic mitral stenosis EDAT- 2018/12/18 06:00 MHDA- 2019/05/29 06:00 CRDT- 2018/12/18 06:00 PHST- 2018/07/02 00:00 [received] PHST- 2018/12/01 00:00 [accepted] PHST- 2018/12/18 06:00 [pubmed] PHST- 2019/05/29 06:00 [medline] PHST- 2018/12/18 06:00 [entrez] AID - 10.1007/s10554-018-1511-1 [pii] AID - 10.1007/s10554-018-1511-1 [doi] PST - ppublish SO - Int J Cardiovasc Imaging. 2019 May;35(5):781-789. doi: 10.1007/s10554-018-1511-1. Epub 2018 Dec 17.