PMID- 30556896
OWN - NLM
STAT- MEDLINE
DCOM- 20191120
LR  - 20191120
IS  - 2284-0729 (Electronic)
IS  - 1128-3602 (Linking)
VI  - 22
IP  - 23
DP  - 2018 Dec
TI  - Nutritional strategies for psoriasis: current scientific evidence in clinical 
      trials.
PG  - 8537-8551
LID - 16554 [pii]
LID - 10.26355/eurrev_201812_16554 [doi]
AB  - OBJECTIVE: Several nutritional strategies for the management of psoriasis are 
      promising. Even if recent data support that nutrition may play a pivotal role in 
      prevention and co-treatment and despite patient's concerns regarding the best 
      nutritional habits, the consensus regarding the nutritional strategies to be 
      adopted lacks in clinical settings. In this manuscript, the effects of several 
      nutritional strategies for psoriasis patients such as hypocaloric diet, vitamin 
      D, fish oil, selenium, and zinc supplementation were systematically reviewed. 
      Randomized controlled trials (RCTs) on beneficial botanical oral supplements were 
      also included in the analysis. MATERIALS AND METHODS: For each topic, a search 
      was conducted in MEDLINE electronic databases for articles published in English 
      between January 1, 1990 and September 2018. Two independent reviewers assessed 
      and extracted the data. Only controlled clinical trials were selected. RESULTS: 
      The evidence regarding the current nutritional strategies for psoriasis patients 
      were summarized and translated into a global, comprehensible recommendation. 
      CONCLUSIONS: Weight loss combined with a healthy lifestyle was shown to be very 
      beneficial for patients with moderate to severe disease with a significant 
      reduction of the Psoriasis Area and Severity Index (PASI) score. Currently, oral 
      vitamin D supplementation for prevention or treatment of psoriasis in adults with 
      normal vitamin D levels is not recommended; however, psoriasis patients with a 
      deficit in plasma vitamin D levels are advised to complement with oral 
      supplements to prevent psoriasis-related comorbidities. Instead of zinc, 
      selenium, and omega 3 supplements have been proven beneficial for psoriasis 
      patients. Among botanical species, Dunaliella bardawil (D. bardawil), 
      Tripterygium wilfordii (T. wilfordii), Azadirachta indica (A. indica), Curcuma 
      longa (C. longa), and HESA-A are the most beneficial. In conclusion, a close 
      cooperation between nutritionists and dermatologists may be useful for the 
      management of psoriasis.
FAU - Zuccotti, E
AU  - Zuccotti E
AD  - Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, 
      Pavia, Italy. paola.rossi@unipv.it.
FAU - Oliveri, M
AU  - Oliveri M
FAU - Girometta, C
AU  - Girometta C
FAU - Ratto, D
AU  - Ratto D
FAU - Di Iorio, C
AU  - Di Iorio C
FAU - Occhinegro, A
AU  - Occhinegro A
FAU - Rossi, P
AU  - Rossi P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Systematic Review
PL  - Italy
TA  - Eur Rev Med Pharmacol Sci
JT  - European review for medical and pharmacological sciences
JID - 9717360
RN  - 0 (Fish Oils)
RN  - 0 (Vitamins)
RN  - 1406-16-2 (Vitamin D)
SB  - IM
MH  - Adult
MH  - Diet, Reducing
MH  - *Dietary Supplements
MH  - Fish Oils
MH  - Humans
MH  - Psoriasis/*diet therapy/drug therapy
MH  - Vitamin D/therapeutic use
MH  - Vitamins/*therapeutic use
EDAT- 2018/12/18 06:00
MHDA- 2019/11/21 06:00
CRDT- 2018/12/18 06:00
PHST- 2018/12/18 06:00 [entrez]
PHST- 2018/12/18 06:00 [pubmed]
PHST- 2019/11/21 06:00 [medline]
AID - 16554 [pii]
AID - 10.26355/eurrev_201812_16554 [doi]
PST - ppublish
SO  - Eur Rev Med Pharmacol Sci. 2018 Dec;22(23):8537-8551. doi: 
      10.26355/eurrev_201812_16554.