PMID- 30557844 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20190122 LR - 20190122 IS - 1873-3557 (Electronic) IS - 1386-1425 (Linking) VI - 211 DP - 2019 Mar 15 TI - Achieving highly sensitive detection of Cu(2+) based on AIE and FRET strategy in aqueous solution. PG - 272-279 LID - S1386-1425(18)31083-7 [pii] LID - 10.1016/j.saa.2018.12.020 [doi] AB - The aggregation-induced emission (AIE) luminogens are now showing strong potential in mimicking the energy donor of fluorescence resonance energy transfer (FRET) system. Herein, one highly efficient FRET system 1-NiR is successfully fabricated in aqueous solution based on an AIE active compound 1 and fluorescence dyes (Nile red (NiR)). 1 acts as the energy donor and NiR acts as the acceptor in the FRET system with the optimum concentrations ratio [1]/[NiR] = 100. Besides, the AIE(1) itself displays excellent selectivity for Cu(2+) ions at 525 nm with the detection limit of 1.32 x 10(-7) M. While through the FRET system of 1-NiR system, the detection limit of Cu(2+) can be further decreased to 9.12 nM by monitoring the fluorescence at 630 nm. As a result, using an AIE probe to detect Cu(2+) based on FRET mechanism is a promising strategy. CI - Copyright (c) 2018. Published by Elsevier B.V. FAU - Yang, Jianting AU - Yang J AD - Key Laboratory of Chemical Biology, Molecular Engineering of Ministry of Education, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. FAU - Chai, Jie AU - Chai J AD - Key Laboratory of Chemical Biology, Molecular Engineering of Ministry of Education, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. FAU - Yang, Binsheng AU - Yang B AD - Key Laboratory of Chemical Biology, Molecular Engineering of Ministry of Education, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. Electronic address: yangbs@sxu.edu.cn. FAU - Liu, Bin AU - Liu B AD - Key Laboratory of Chemical Biology, Molecular Engineering of Ministry of Education, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. Electronic address: liubin@sxu.edu.cn. LA - eng PT - Journal Article DEP - 20181211 PL - England TA - Spectrochim Acta A Mol Biomol Spectrosc JT - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy JID - 9602533 OTO - NOTNLM OT - Aggregation-induced emission OT - Cu(2+) OT - Fluorescence resonance energy transfer OT - Nile red EDAT- 2018/12/18 06:00 MHDA- 2018/12/18 06:01 CRDT- 2018/12/18 06:00 PHST- 2018/10/08 00:00 [received] PHST- 2018/11/28 00:00 [revised] PHST- 2018/12/09 00:00 [accepted] PHST- 2018/12/18 06:00 [pubmed] PHST- 2018/12/18 06:01 [medline] PHST- 2018/12/18 06:00 [entrez] AID - S1386-1425(18)31083-7 [pii] AID - 10.1016/j.saa.2018.12.020 [doi] PST - ppublish SO - Spectrochim Acta A Mol Biomol Spectrosc. 2019 Mar 15;211:272-279. doi: 10.1016/j.saa.2018.12.020. Epub 2018 Dec 11.