PMID- 30560101
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220330
IS  - 2251-7251 (Print)
IS  - 2251-726X (Electronic)
IS  - 2251-7251 (Linking)
VI  - 30
IP  - 101
DP  - 2018 Nov
TI  - Eosinophilic Mucin Rhinosinusitis in Iranian Patients Undergoing Endoscopic Sinus 
      Surgery.
PG  - 347-353
AB  - INTRODUCTION: Eosinophilic mucin rhinosinusitis is a type of chronic 
      rhinosinusitis (CRS). Diagnosis and treatment of this condition play a 
      significant role in reducing the patients' clinical symptoms. This type of 
      rhinosinusitis has a higher relapse rate, compared to the other types. This 
      disease is more resistant to treatment and more dependent on corticosteroid 
      therapy, compared to the other types of rhinosinusitis. Regarding this, the 
      present study was designed to evaluate the frequency of eosinophilic mucin 
      rhinosinusitis in patients undergoing sinus surgery in a tertiary referral center 
      and examine some clinical and laboratory characteristics regarding this type of 
      rhinosinusitis. MATERIALS AND METHODS: This cross-sectional observational study 
      was performed on patients over the age of 16 years, who were diagnosed with CRS 
      in the otolaryngology clinic of a referral tertiary-level hospital, and were 
      candidates for endoscopic sinus surgery. Based on the detection of eosinophilic 
      mucin, the subjects were divided into two groups of eosinophilic mucin and 
      non-eosinophilic mucin rhinosinusitis (controls). The groups were compared in 
      terms of sino-nasal outcome test (SNOT-22) scores, Lund-Mackay staging scores, 
      osteitis status, immunoglobulin E (IgE) level, and eosinophilia. RESULTS: In this 
      study, 46 subjects participated, 29 (63%) cases of whom had eosinophilic mucin. 
      The SNOT-22 score and serum IgE level were significantly higher in the 
      eosinophilic mucin group, compared to those in the control group. Osteitis and 
      Lund-Mackay scores were also higher in the eosinophilic mucin group than those in 
      the control group; however, this difference was not statistically significant. 
      CONCLUSION: Patients with eosinophilic mucin rhinosinusitis showed a more severe 
      clinical involvement. Seemingly, the Iranian patients have a lower and higher 
      frequency of eosinophilic mucin rhinosinusitis, compared to the patients from the 
      Western countries and East Asia, respectively.
FAU - Ghorbani, Jahangir
AU  - Ghorbani J
AD  - Chronic Respiratory Diseases Research Center,National Research Institute of 
      Tubeclosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical 
      Sciences, Tehran, Iran.
FAU - Hosseini Vajari, Ali
AU  - Hosseini Vajari A
AD  - Department of Otolaryngology,DR. Masih Daneshvari Hospital, Shahid Beheshti 
      University of Medical Sciences, Tehran, Iran.
FAU - Pourdowlat, Guitti
AU  - Pourdowlat G
AD  - Chronic Respiratory Diseases Research Center, Shahid Beheshti University of 
      Medical Sciences, Tehran, Iran.
FAU - Ghasemi, Parisa
AU  - Ghasemi P
AD  - Department of Otolaryngology,DR. Masih Daneshvari Hospital, Shahid Beheshti 
      University of Medical Sciences, Tehran, Iran.
FAU - Eskandari, Yousef
AU  - Eskandari Y
AD  - Department of Otolaryngology,DR. Masih Daneshvari Hospital, Shahid Beheshti 
      University of Medical Sciences, Tehran, Iran.
FAU - Ghasemi, Keyvan
AU  - Ghasemi K
AD  - Medical student ,Student Research Committee,Arak University of Medical Sciences, 
      Arak ,Iran.
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Iran J Otorhinolaryngol
JT  - Iranian journal of otorhinolaryngology
JID - 101577699
PMC - PMC6291821
OTO - NOTNLM
OT  - Chronic
OT  - Eosinophilic
OT  - IgE
OT  - Mucin
OT  - Nasal polyps
OT  - Osteitis
OT  - Rhinitis
OT  - Sinusitis
EDAT- 2018/12/19 06:00
MHDA- 2018/12/19 06:01
PMCR- 2018/11/01
CRDT- 2018/12/19 06:00
PHST- 2018/12/19 06:00 [entrez]
PHST- 2018/12/19 06:00 [pubmed]
PHST- 2018/12/19 06:01 [medline]
PHST- 2018/11/01 00:00 [pmc-release]
AID - ijo-30-347 [pii]
PST - ppublish
SO  - Iran J Otorhinolaryngol. 2018 Nov;30(101):347-353.