PMID- 30560269 OWN - NLM STAT- MEDLINE DCOM- 20190522 LR - 20190522 IS - 0371-0874 (Print) IS - 0371-0874 (Linking) VI - 70 IP - 6 DP - 2018 Dec 25 TI - [Hyperhomocysteinemia and kidney diseases]. PG - 607-611 AB - Homocysteine (Hcy) is an intermediate metabolite of methionine metabolism. Hyperhomocysteinemia (HHcy) is defined as a condition characterized by plasma Hcy level above 16 mumol/L which can result from abnormal Hcy metabolism. HHcy has been confirmed to be related to cardio-cerebrovascular disease, peripheral vascular disorders, neurodegenerative diseases, diabetes, pregnancy-induced hypertension syndrome, liver cirrhosis and kidney diseases. In this review, we summarize the correlation between HHcy and kidney diseases. Elucidating the role of HHcy in kidney diseases may provide a new strategy to prevent and treat kidney diseases. FAU - Zhou, Yun-Feng AU - Zhou YF AD - Medical Research Center, Physiology Department of Basic Medical College, Shenzhen University Health Science Center, Shenzhen 518060, China. FAU - Guan, You-Fei AU - Guan YF AD - Advanced Institute of Medical Sciences, Dalian Medical University, Dalian 116044, China. guanyf@dmu.edu.cn. LA - chi PT - Journal Article PT - Review PL - China TA - Sheng Li Xue Bao JT - Sheng li xue bao : [Acta physiologica Sinica] JID - 20730130R RN - 0LVT1QZ0BA (Homocysteine) SB - IM MH - Homocysteine MH - Humans MH - Hyperhomocysteinemia/*complications MH - Kidney Diseases/*complications EDAT- 2018/12/19 06:00 MHDA- 2019/05/23 06:00 CRDT- 2018/12/19 06:00 PHST- 2018/12/19 06:00 [entrez] PHST- 2018/12/19 06:00 [pubmed] PHST- 2019/05/23 06:00 [medline] PST - ppublish SO - Sheng Li Xue Bao. 2018 Dec 25;70(6):607-611.