PMID- 30569378 OWN - NLM STAT- MEDLINE DCOM- 20190327 LR - 20200225 IS - 1613-2246 (Electronic) IS - 0021-5155 (Linking) VI - 63 IP - 2 DP - 2019 Mar TI - Influence of irrigation dynamic pressure-assisted hydrodissection on intraocular pressure and the posterior chamber-anterior hyaloid membrane barrier during cataract surgery. PG - 221-228 LID - 10.1007/s10384-018-00646-3 [doi] AB - PURPOSE: To evaluate the effects of irrigation dynamic pressure-assisted hydrodissection (irrigation-hydro: iH) on intraocular pressure (IOP) and the posterior chamber-anterior hyaloid membrane (PC-AHM) barrier in porcine eyes. STUDY DESIGN: Experimental. METHODS: In Experiment 1, IOP was recorded while irrigating the anterior chamber (AC), during iH, and during phacoemulsification and aspiration in 20 porcine eyes using bottle heights of 50, 70, and 90 cm. Under the same conditions, IOP was recorded during conventional manual cortical cleaving hydrodissection (manual hydro: mH) in 20 porcine eyes. In Experiment 2, after iH, ACs were perfused for 5 seconds with balanced salt solution containing 1.0-mum fluorescein beads in 20 porcine eyes using bottle heights of 70, 118, and 169 cm. PC-AHM barrier staining grade was evaluated by the Miyake-Apple view. RESULTS: iH proved successful in all cases. In Experiment 1, IOP during iH was relatively stable and peak IOP was below the baseline bottle height-dependent pressure. No eyes showed a peak IOP > 75 mmHg during iH, but 8 eyes showed a peak IOP > 75 mmHg during mH. In Experiment 2, neither AHT nor ruptured capsules were observed at any bottle height. CONCLUSION: Unlike mH, IOP during iH was relatively stable without any high peak IOP. Thus, iH offers a simple technique for reducing peak IOP and avoiding disturbance of the PC-AHM barrier. FAU - Kato, Noriko AU - Kato N AD - Department of Ophthalmology, School of Medicine, The Jikei University, 3-25-8 Nishishinbashi, Minato-ku, Tokyo, 105-8461, Japan. mapletown@hotmail.co.jp. FAU - Masuda, Yoichiro AU - Masuda Y AD - Department of Ophthalmology, School of Medicine, The Jikei University, 3-25-8 Nishishinbashi, Minato-ku, Tokyo, 105-8461, Japan. FAU - Oki, Kotaro AU - Oki K AD - Oki Eye Surgery Center, Tokyo, Japan. FAU - Iwaki, Hisaharu AU - Iwaki H AD - Iwaki Eye Clinic, Tokyo, Japan. FAU - Tsuneoka, Hiroshi AU - Tsuneoka H AD - Department of Ophthalmology, School of Medicine, The Jikei University, 3-25-8 Nishishinbashi, Minato-ku, Tokyo, 105-8461, Japan. LA - eng PT - Journal Article DEP - 20181219 PL - Japan TA - Jpn J Ophthalmol JT - Japanese journal of ophthalmology JID - 0044652 SB - IM MH - Animals MH - Anterior Chamber/*metabolism MH - Disease Models, Animal MH - Intraocular Pressure/*physiology MH - *Intraoperative Complications MH - Lens Implantation, Intraocular/*methods MH - Membranes/*pathology MH - Phacoemulsification/*methods MH - Pressure MH - Swine MH - Therapeutic Irrigation/*methods OTO - NOTNLM OT - Anterior hyaloid membrane tear OT - Capsular block syndrome OT - Hydrodissection-related complication OT - Infusion misdirection syndrome OT - Low-invasive cataract surgery EDAT- 2018/12/21 06:00 MHDA- 2019/03/28 06:00 CRDT- 2018/12/21 06:00 PHST- 2017/04/12 00:00 [received] PHST- 2018/11/05 00:00 [accepted] PHST- 2018/12/21 06:00 [pubmed] PHST- 2019/03/28 06:00 [medline] PHST- 2018/12/21 06:00 [entrez] AID - 10.1007/s10384-018-00646-3 [pii] AID - 10.1007/s10384-018-00646-3 [doi] PST - ppublish SO - Jpn J Ophthalmol. 2019 Mar;63(2):221-228. doi: 10.1007/s10384-018-00646-3. Epub 2018 Dec 19.