PMID- 30576087
OWN - NLM
STAT- MEDLINE
DCOM- 20200303
LR  - 20200303
IS  - 2042-6984 (Electronic)
IS  - 2042-6976 (Linking)
VI  - 9
IP  - 5
DP  - 2019 May
TI  - Blood eosinophils may predict radiographic sinus opacification in patients with 
      chronic rhinitis.
PG  - 522-527
LID - 10.1002/alr.22270 [doi]
AB  - BACKGROUND: The association between chronic rhinosinusitis (CRS) and chronic 
      rhinitis remains unclear. The aim of this study was to estimate the predictive 
      factors for sinus opacification in chronic rhinitis patients without obvious CRS. 
      METHODS: We retrospectively studied a total of 332 adult patients with chronic 
      rhinitis who visited our clinic from January 2015 to December 2017. All of the 
      patients underwent endoscopic examination, allergy test, and osteomeatal-unit 
      computed tomography. The subjects were assigned to the normal sinus (NS) group 
      (Lund-Mackay score [LMS] <5) and sinus opacification (SO) group (LMS >/=5). 
      RESULTS: A total of 288 patients were eligible for this study. Of them, 183 
      (63.5%) were classified in the NS group and 105 (36.5%) in the SO group. Total 
      immunoglobulin E (IgE) level and peripheral blood eosinophil count were 
      significantly higher in the SO than NS group (p = 0.031 and p < 0.0001, 
      respectively). Using Pearson correlation coefficients, we determined that 
      eosinophil count had a positive correlation with the LMS (r = 0.282). In logistic 
      analysis, the interquartile range increase (0.19 x 10(9) /L) of the eosinophil 
      count was significantly associated with SO (odds ratio [OR] 1.76; 95% confidence 
      interval [CI], 1.30 to 2.39). After adjusting for age, gender, smoking, drinking, 
      and underlying disease, the interquartile range increase of the eosinophil count 
      increased the odds of SO to 1.69-fold; this increase was statistically 
      significant (p = 0.007; 95% CI, 1.17 to 2.43). CONCLUSION: Peripheral blood 
      eosinophil count is an independent predictor of CRS in patients with chronic 
      rhinitis.
CI  - (c) 2018 ARS-AAOA, LLC.
FAU - Oh, Seung Yong
AU  - Oh SY
AD  - Department of Otolaryngology, National Police Hospital, Seoul, Korea.
FAU - Hwang, Junho
AU  - Hwang J
AD  - Department of Otolaryngology, National Police Hospital, Seoul, Korea.
FAU - Ryu, Yoon-Jong
AU  - Ryu YJ
AD  - Department of Otolaryngology, Kangwon National University Hospital, Chuncheon, 
      Korea.
FAU - Won, Jun Yeon
AU  - Won JY
AD  - Department of Otolaryngology, Kangwon National University Hospital, Chuncheon, 
      Korea.
FAU - Kwon, Sung Ok
AU  - Kwon SO
AD  - Biomedical Research Institute, Kangwon National University Hospital, Chuncheon, 
      Korea.
FAU - Lee, Woo Hyun
AU  - Lee WH
AD  - Department of Otolaryngology, Kangwon National University Hospital, Chuncheon, 
      Korea.
LA  - eng
PT  - Journal Article
DEP - 20181221
PL  - United States
TA  - Int Forum Allergy Rhinol
JT  - International forum of allergy & rhinology
JID - 101550261
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Chronic Disease
MH  - Endoscopy
MH  - Eosinophils/*immunology
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/blood/immunology
MH  - Leukocyte Count
MH  - Male
MH  - Middle Aged
MH  - Paranasal Sinuses/*diagnostic imaging
MH  - Rhinitis/diagnostic imaging/*immunology
MH  - Sinusitis/*diagnosis/immunology
MH  - Tomography, X-Ray Computed
OTO - NOTNLM
OT  - allergic rhinitis
OT  - computed tomography
OT  - eosinophils
OT  - rhinitis
OT  - sinusitis
EDAT- 2018/12/24 06:00
MHDA- 2020/03/04 06:00
CRDT- 2018/12/22 06:00
PHST- 2018/08/18 00:00 [received]
PHST- 2018/11/12 00:00 [revised]
PHST- 2018/11/29 00:00 [accepted]
PHST- 2018/12/24 06:00 [pubmed]
PHST- 2020/03/04 06:00 [medline]
PHST- 2018/12/22 06:00 [entrez]
AID - 10.1002/alr.22270 [doi]
PST - ppublish
SO  - Int Forum Allergy Rhinol. 2019 May;9(5):522-527. doi: 10.1002/alr.22270. Epub 
      2018 Dec 21.