PMID- 30577033 OWN - NLM STAT- MEDLINE DCOM- 20191218 LR - 20191218 IS - 1361-6560 (Electronic) IS - 0031-9155 (Linking) VI - 64 IP - 3 DP - 2019 Jan 31 TI - Multi-energy computed tomography reconstruction using a nonlocal spectral similarity model. PG - 035018 LID - 10.1088/1361-6560/aafa99 [doi] AB - Multi-energy computed tomography (MECT) is able to acquire simultaneous multi-energy measurements from one scan. In addition, it allows material differentiation and quantification effectively. However, due to the limited energy bin width, the number of photons detected in an energy-specific channel is smaller than that in traditional CT, which results in image quality degradation. To address this issue, in this work, we develop a statistical iterative reconstruction algorithm to acquire high-quality MECT images and high-accuracy material-specific images. Specifically, this algorithm fully incorporates redundant self-similarities within nonlocal regions in the MECT image at one bin and rich spectral similarities among MECT images at all bins. For simplicity, the presented algorithm is referred to as 'MECT-NSS'. Moreover, an efficient optimization algorithm is developed to solve the MECT-NSS objective function. Then, a comprehensive evaluation of parameter selection for the MECT-NSS algorithm is conducted. In the experiment, the datasets include images from three phantoms and one patient to validate and evaluate the MECT-NSS reconstruction performance. The qualitative and quantitative results demonstrate that the presented MECT-NSS can successfully yield better MECT image quality and more accurate material estimation than the competing algorithms. FAU - Yao, Lisha AU - Yao L AD - School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, People's Republic of China. Guangzhou Key Laboratory of Medical Radiation Imaging and Detection Technology, Southern Medical University, Guangzhou 510515, People's Republic of China. These authors contributed equally. FAU - Zeng, Dong AU - Zeng D FAU - Chen, Gaofeng AU - Chen G FAU - Liao, Yuting AU - Liao Y FAU - Li, Sui AU - Li S FAU - Zhang, Yuanke AU - Zhang Y FAU - Wang, Yongbo AU - Wang Y FAU - Tao, Xi AU - Tao X FAU - Niu, Shanzhou AU - Niu S FAU - Lv, Qingwen AU - Lv Q FAU - Bian, Zhaoying AU - Bian Z FAU - Ma, Jianhua AU - Ma J FAU - Huang, Jing AU - Huang J LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20190131 PL - England TA - Phys Med Biol JT - Physics in medicine and biology JID - 0401220 SB - IM MH - Algorithms MH - Humans MH - Image Processing, Computer-Assisted/*methods MH - *Models, Statistical MH - Phantoms, Imaging MH - Photons MH - *Tomography, X-Ray Computed EDAT- 2018/12/24 06:00 MHDA- 2019/12/19 06:00 CRDT- 2018/12/22 06:00 PHST- 2018/12/24 06:00 [pubmed] PHST- 2019/12/19 06:00 [medline] PHST- 2018/12/22 06:00 [entrez] AID - 10.1088/1361-6560/aafa99 [doi] PST - epublish SO - Phys Med Biol. 2019 Jan 31;64(3):035018. doi: 10.1088/1361-6560/aafa99.