PMID- 30579047
OWN - NLM
STAT- MEDLINE
DCOM- 20200505
LR  - 20200505
IS  - 1872-6968 (Electronic)
IS  - 0303-8467 (Linking)
VI  - 177
DP  - 2019 Feb
TI  - MR T2 image classi fi cation in adult patients of cervical spinal cord injury 
      without radiographic abnormality: A predictor of surgical outcome.
PG  - 1-5
LID - S0303-8467(18)30467-0 [pii]
LID - 10.1016/j.clineuro.2018.12.010 [doi]
AB  - OBJECTIVES: Although patients with cervical spinal cord injury without 
      radiographic abnormality (SCIWORA) present increased signal intensity (ISI) on 
      magnetic resonance imaging (MRI), its degree has not been examined. This study 
      evaluated the clinical effectiveness of MRI-based ISI in adult patients of 
      SCIWORA. Its predictive value for symptom severity was also evaluated. PATIENTS 
      AND METHODS: One-hundred consecutive SCIWORA patients who had undergone expansive 
      laminoplasty were enrolled. Among them, 79 were male and 21 were female. The mean 
      age was 55 years (range 20-87). All patients underwent MRI in the acute phase, 
      and ISI was classi fi ed into three groups based on sagittal T2-weighted MRI: Grade 
      0, none; Grade 1, light (obscure); and Grade 2, intense (bright). The pre- and 
      postoperative neurological status was evaluated using the Japanese Orthopaedic 
      Association scoring system for cervical myelopathy (JOA score) and the ASIA 
      impairment scale (AIS). RESULTS: Preoperative MRI showed Grade 0 in 8 patients, 
      Grade 1 in 49 patients, and Grade 2 in 43 patients. There were no differences in 
      age and gender among three groups. The pre- and postoperative JOA scores 
      decreased significantly with an increasing ISI grade. The recovery rate of JOA 
      score decreased with the ISI grade. The ISI grade tended to increase with the 
      pre- and postoperative AIS grades. ISI Grade 2 on MRI was observed in severely 
      paralyzed cases. CONCLUSIONS: MRI-based ISI classi fi cation is correlated with 
      preoperative symptom severity in adult patients with SCIWORA and can be a 
      predictor of surgical outcome.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Machino, Masaaki
AU  - Machino M
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Ando, Kei
AU  - Ando K
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Kobayashi, Kazuyoshi
AU  - Kobayashi K
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Ota, Kyotaro
AU  - Ota K
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Morozumi, Masayoshi
AU  - Morozumi M
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Tanaka, Satoshi
AU  - Tanaka S
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Ito, Keigo
AU  - Ito K
AD  - Department of Orthopedic Surgery and Radiology, Chubu Rosai Hospital, Japan 
      Organization of Occupational Health and Safety, Nagoya, Japan.
FAU - Kato, Fumihiko
AU  - Kato F
AD  - Department of Orthopedic Surgery and Radiology, Chubu Rosai Hospital, Japan 
      Organization of Occupational Health and Safety, Nagoya, Japan.
FAU - Ishiguro, Naoki
AU  - Ishiguro N
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Imagama, Shiro
AU  - Imagama S
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan. Electronic address: imagama@med.nagoya-u.ac.jp.
LA  - eng
PT  - Journal Article
DEP - 20181214
PL  - Netherlands
TA  - Clin Neurol Neurosurg
JT  - Clinical neurology and neurosurgery
JID - 7502039
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cervical Cord/*diagnostic imaging/surgery
MH  - Cervical Vertebrae/*surgery
MH  - Female
MH  - Humans
MH  - Laminoplasty/methods
MH  - Magnetic Resonance Imaging/methods
MH  - Male
MH  - Middle Aged
MH  - Neck Injuries/surgery
MH  - Spinal Cord Compression/surgery
MH  - Spinal Cord Diseases/diagnostic imaging/surgery
MH  - Spinal Cord Injuries/*surgery
MH  - Treatment Outcome
MH  - Young Adult
OTO - NOTNLM
OT  - Cervical spinal cord injury without radiographic abnormality
OT  - Image classi fi cation
OT  - Increased signal intensity
OT  - Magnetic resonance imaging
OT  - Surgical outcome
EDAT- 2018/12/24 06:00
MHDA- 2020/05/06 06:00
CRDT- 2018/12/23 06:00
PHST- 2018/10/09 00:00 [received]
PHST- 2018/12/05 00:00 [revised]
PHST- 2018/12/13 00:00 [accepted]
PHST- 2018/12/24 06:00 [pubmed]
PHST- 2020/05/06 06:00 [medline]
PHST- 2018/12/23 06:00 [entrez]
AID - S0303-8467(18)30467-0 [pii]
AID - 10.1016/j.clineuro.2018.12.010 [doi]
PST - ppublish
SO  - Clin Neurol Neurosurg. 2019 Feb;177:1-5. doi: 10.1016/j.clineuro.2018.12.010. 
      Epub 2018 Dec 14.