PMID- 30585598
OWN - NLM
STAT- MEDLINE
DCOM- 20190605
LR  - 20190605
IS  - 1997-7298 (Print)
IS  - 1997-7298 (Linking)
VI  - 118
IP  - 11
DP  - 2018
TI  - [Personality disorders and schizophrenic defect (problem of comorbidity)].
PG  - 4-14
LID - 10.17116/jnevro20181181114 [doi]
AB  - AIM: To test the main hypothesis that the deficit phenomena in schizophrenia act 
      not in the 'pure' form, but in the form of aggravating personality 
      characteristics, forming so-called 'common' syndromes with personality disorders 
      (PD). MATERIAL AND METHODS: The results of the psychopathological study (with the 
      use of psychometric methods) of deficit disorders in a sample of 170 patients 
      with schizophrenia and schizophrenia spectrum disorders (63 men, 107 women) are 
      presented in relation to the abnormal structure of premorbid personality (PD of 
      clusters A, B, C). An analysis of negative symptoms according to the 
      comparability of defect to the profile of premorbid personality made it possible 
      to distinguish three groups of deficit states associated with PD - 'common 
      syndromes': defensive schizoidy by the type of deficit schizoid and expansive 
      schizoidy by the type of 'verschroben' (cluster A); pathological hysterical 
      infantilism, malignant hysteria and defective erotomania (cluster B); 
      pseudo-psychasthenia and pathological rationalism (cluster C). RESULTS: It has 
      been found that the symptomatology of 'common syndromes' is subject to patterns 
      reflecting the dichotomy of the basic defect. This pattern is valid not only for 
      one single cluster of PD, but extends to all psychopathy-like disorders, 
      regardless of their affiliation with a particular cluster. The 
      pathocharacterological component of the 'common syndromes' coexisting with the 
      deficit symptom complexes is subject to the basic deficit component of the defect 
      and is separated into polar dimensions (defensive-expansive) within specific 
      clusters of PD, and then unified in accordance with the dichotomy of 
      schizophrenic defect in categories with the predominance of emotional or 
      apathoabulic disorders. CONCLUSION: Psychopathy-like symptom complexes in the 
      space of 'common syndromes' can be qualified as a psychopathological construct 
      secondary to basic deficit disorders, and their isolation as an independent 
      entity of negative disorders appears to be unjustified.
FAU - Smulevich, A B
AU  - Smulevich AB
AD  - Mental Health Research Center, Moscow, Russia; Sechenov First Moscow State 
      Medical University, Moscow, Russia.
FAU - Dubnitskaya, E B
AU  - Dubnitskaya EB
AD  - Mental Health Research Center, Moscow, Russia.
FAU - Lobanova, V M
AU  - Lobanova VM
AD  - Mental Health Research Center, Moscow, Russia.
FAU - Voronova, E I
AU  - Voronova EI
AD  - Mental Health Research Center, Moscow, Russia; Sechenov First Moscow State 
      Medical University, Moscow, Russia.
FAU - Zhylin, V O
AU  - Zhylin VO
AD  - Mental Health Research Center, Moscow, Russia.
FAU - Kolyutskaya, E V
AU  - Kolyutskaya EV
AD  - Mental Health Research Center, Moscow, Russia; Sechenov First Moscow State 
      Medical University, Moscow, Russia.
FAU - Samoilova, E D
AU  - Samoilova ED
AD  - Sechenov First Moscow State Medical University, Moscow, Russia.
FAU - Sorokina, O Yu
AU  - Sorokina OY
AD  - Mental Health Research Center, Moscow, Russia.
LA  - rus
PT  - Journal Article
TT  - Rasstroistva lichnosti i shizofrenicheskii defekt (problema komorbidnosti).
PL  - Russia (Federation)
TA  - Zh Nevrol Psikhiatr Im S S Korsakova
JT  - Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
JID - 9712194
SB  - IM
MH  - Comorbidity
MH  - Female
MH  - Humans
MH  - Male
MH  - *Personality Disorders
MH  - Psychometrics
MH  - Psychopathology
MH  - *Schizophrenia
MH  - *Schizophrenic Psychology
OTO - NOTNLM
OT  - personality disorders
OT  - primary/basic disorders
OT  - schizophrenia
OT  - schizophrenia spectrum disorders
OT  - <<common syndromes>>
EDAT- 2018/12/27 06:00
MHDA- 2019/06/06 06:00
CRDT- 2018/12/27 06:00
PHST- 2018/12/27 06:00 [entrez]
PHST- 2018/12/27 06:00 [pubmed]
PHST- 2019/06/06 06:00 [medline]
AID - 10.17116/jnevro20181181114 [doi]
PST - ppublish
SO  - Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(11):4-14. doi: 
      10.17116/jnevro20181181114.