PMID- 30588901
OWN - NLM
STAT- MEDLINE
DCOM- 20191030
LR  - 20191030
IS  - 1475-2662 (Electronic)
IS  - 0007-1145 (Linking)
VI  - 121
IP  - 1
DP  - 2019 Jan
TI  - Effect of pre-exercise ingestion of alpha-lactalbumin on subsequent endurance 
      exercise performance and mood states.
PG  - 22-29
LID - 10.1017/S000711451800274X [doi]
AB  - This study investigated the effect of pre-exercise alpha-lactalbumin ingestion on 
      subsequent endurance exercise performance, muscle pain and mood states. In a 
      two-stage cross-over counterbalance design, eleven male endurance runners (age: 
      31 (se 2) years, height: 169.5 (se 4.4) cm, weight: 63.6 (se 5.1) kg, V̇O2max: 
      58.8 (se 6.3) ml/kg per min) consumed two solutions (carbohydrate+alpha-lactalbumin, 
      CA; carbohydrate+whey protein isolate, CW) 2 h before a self-paced 21-km run. 
      Creatine kinase, IL-6, muscle pain, pressure pain threshold (PPT) and mood states 
      were assessed 2 h before exercise, immediately before exercise (Pre-ex0) and 
      immediately after exercise (Post-ex0). No difference was found in 21-km running 
      performance between two trials (CA v. CW: 115.85 (se 5.20) v. 118.85 (se 5.51) 
      min, P=0.48). Compared with CW, CA led to higher PPT at Pre-ex0 (41.77 (se 2.27) 
      v. 35.56 (se 2.10) N/cm2, P<0.01) and Post-ex0 (38.76 (se 3.23) v. 35.30 (se 
      3.55) N/cm2, P=0.047). Compared with CW, CA reduced the feeling of fatigue at 
      Post-ex0 (P<0.01); CA also reduced salivary cortisol levels at Post-ex0 (0.72 
      (se 0.07) v. 0.83 (se 0.13) ng/ml, P<0.01). In conclusion, the ingestion of 
      alpha-lactalbumin did not improve the 21-km time-trial performance. However, compared 
      with the pre-exercise ingestion of whey protein, that of alpha-lactalbumin led to 
      superior results during similar levels of endurance exercise: it elevated PPT and 
      reduced the feeling of fatigue and the cortisol levels.
FAU - Qin, Lu
AU  - Qin L
AD  - 1Department of Sports Science and Physical Education,The Chinese University of 
      Hong Kong,Shatin,Hong Kong, 00852.
FAU - Sun, Feng-Hua
AU  - Sun FH
AD  - 3Department of Health and Physical Education,The Education University of Hong 
      Kong,Tai Po,Hong Kong, 00852.
FAU - Huang, Yu
AU  - Huang Y
AD  - 4Institute of Vascular Medicine,School of Biomedical Sciences and Li Ka Shing 
      Institute of Health Sciences,The Chinese University of Hong Kong,Shatin,Hong 
      Kong, 00852.
FAU - Sheridan, Sinead
AU  - Sheridan S
AD  - 5Li Ka Shing Faculty of Medicine,School of Public Health,The University of Hong 
      Kong,Pokfulam,Hong Kong, 00852.
FAU - Sit, Cindy Hui-Ping
AU  - Sit CH
AD  - 1Department of Sports Science and Physical Education,The Chinese University of 
      Hong Kong,Shatin,Hong Kong, 00852.
FAU - Wong, Stephen Heung-Sang
AU  - Wong SH
AD  - 1Department of Sports Science and Physical Education,The Chinese University of 
      Hong Kong,Shatin,Hong Kong, 00852.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
RN  - 0 (Interleukin-6)
RN  - 0 (Whey Proteins)
RN  - 9013-90-5 (Lactalbumin)
RN  - EC 2.7.3.2 (Creatine Kinase)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Adult
MH  - Affect/*drug effects/physiology
MH  - Athletic Performance/*physiology
MH  - Creatine Kinase/blood
MH  - Cross-Over Studies
MH  - Exercise/*physiology
MH  - Fatigue
MH  - Humans
MH  - Hydrocortisone/analysis/blood
MH  - Interleukin-6/blood
MH  - Lactalbumin/*administration & dosage
MH  - Male
MH  - Myalgia
MH  - Oxygen Consumption
MH  - Pain Threshold/drug effects
MH  - Physical Endurance/*drug effects/physiology
MH  - Running/physiology
MH  - Saliva/chemistry
MH  - Whey Proteins/administration & dosage
OTO - NOTNLM
OT  - AD abdominal discomfort
OT  - BG blood glucose
OT  - BW body weight
OT  - CA carbohydrate+alpha-lactalbumin
OT  - CHO carbohydrate
OT  - CK creatine kinase
OT  - CW carbohydrate+whey protein isolated
OT  - LA lactic acid
OT  - PPT pressure pain threshold
OT  - PRO protein
OT  - Post-ex0 immediately after exercise
OT  - Pre-ex0 immediately before exercise
OT  - Pre-ex2h 2 h before exercise
OT  - TT time trial
OT  - Half-marathons
OT  - Pain
OT  - Stress
OT  - Time trials
EDAT- 2018/12/28 06:00
MHDA- 2019/10/31 06:00
CRDT- 2018/12/28 06:00
PHST- 2018/12/28 06:00 [entrez]
PHST- 2018/12/28 06:00 [pubmed]
PHST- 2019/10/31 06:00 [medline]
AID - S000711451800274X [pii]
AID - 10.1017/S000711451800274X [doi]
PST - ppublish
SO  - Br J Nutr. 2019 Jan;121(1):22-29. doi: 10.1017/S000711451800274X.