PMID- 3059798
OWN - NLM
STAT- MEDLINE
DCOM- 19890125
LR  - 20190626
IS  - 0002-9343 (Print)
IS  - 0002-9343 (Linking)
VI  - 85
IP  - 6A
DP  - 1988 Dec 23
TI  - Juvenile rheumatoid arthritis, human leukocyte antigen, and other immunoglobulin 
      supergene family polymorphisms.
PG  - 26-8
AB  - The following four points are discussed in this study: (1) Human leukocyte 
      antigen (HLA) genes are associated with all groups of juvenile rheumatoid 
      arthritis patients to varying degrees. (2) These HLA associations are similar to 
      those of some adult inflammatory arthropathies (rheumatoid arthritis and 
      ankylosing spondylitis), but distinct in others. (3) Predisposition commonly 
      involves a contribution from both of a subject's HLA haplotypes. (4) Unusual 
      immunogenetic aspects include a HLA-DP association, independent of linkage 
      disequilibrium with other class II genes, and a HLA-associated mechanism 
      increasing the relative proportion of girls in the involved sibships.
FAU - Maksymowych, W P
AU  - Maksymowych WP
AD  - Division of Rheumatology, Children's Hospital Medical Center, Cincinnati, Ohio 
      45229-2899.
FAU - Van Kerckhove, C
AU  - Van Kerckhove C
FAU - Glass, D N
AU  - Glass DN
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - Am J Med
JT  - The American journal of medicine
JID - 0267200
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-D Antigens)
RN  - 0 (Immunoglobulin Gm Allotypes)
SB  - IM
MH  - Arthritis, Juvenile/classification/*genetics
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Genetic Linkage
MH  - HLA Antigens/*genetics
MH  - HLA-D Antigens/*genetics
MH  - Haplotypes
MH  - Humans
MH  - Immunoglobulin Gm Allotypes/genetics
MH  - Male
MH  - *Polymorphism, Genetic
MH  - Sex Ratio
RF  - 15
EDAT- 1988/12/23 00:00
MHDA- 1988/12/23 00:01
CRDT- 1988/12/23 00:00
PHST- 1988/12/23 00:00 [pubmed]
PHST- 1988/12/23 00:01 [medline]
PHST- 1988/12/23 00:00 [entrez]
AID - 0002-9343(88)90377-4 [pii]
AID - 10.1016/0002-9343(88)90377-4 [doi]
PST - ppublish
SO  - Am J Med. 1988 Dec 23;85(6A):26-8. doi: 10.1016/0002-9343(88)90377-4.