PMID- 30603739
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240420
IS  - 2589-0514 (Electronic)
IS  - 2095-882X (Print)
IS  - 2095-882X (Linking)
VI  - 4
IP  - 4
DP  - 2018 Dec
TI  - Selectins modify dendritic cells during atherosclerosis.
PG  - 205-210
LID - 10.1016/j.cdtm.2018.03.001 [doi]
AB  - Dendritic cells (DCs) are professional antigen-presenting cells (APC) that 
      facilitate the development and progression of atherosclerosis. However, DCs also 
      function as novel "switches" between immune activation and immune tolerance and 
      represent a heterogeneous hematopoietic lineage, with cell subsets in different 
      tissues that show a differential morphology, phenotype, and function. Regulatory 
      DCs, depending on their immature state, can be induced by immunosuppressive 
      modulation, which plays an important part in the maintenance of immunologic 
      tolerance via suppression of the immune response. In this review, we describe the 
      current understanding of the generation of regulatory DCs. The novel role of 
      selectins in the modification of DCs in atherosclerosis is also discussed.
FAU - Ye, Zhi-Shuai
AU  - Ye ZS
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning 116011, China.
FAU - Huang, Rong-Chong
AU  - Huang RC
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning 116011, China.
LA  - eng
PT  - Journal Article
DEP - 20180426
PL  - United States
TA  - Chronic Dis Transl Med
JT  - Chronic diseases and translational medicine
JID - 101679934
PMC - PMC6308906
OTO - NOTNLM
OT  - Atherosclerosis
OT  - Dendritic cells
OT  - Immune tolerance
OT  - Selectins
EDAT- 2019/01/04 06:00
MHDA- 2019/01/04 06:01
PMCR- 2018/04/26
CRDT- 2019/01/04 06:00
PHST- 2018/01/31 00:00 [received]
PHST- 2019/01/04 06:00 [entrez]
PHST- 2019/01/04 06:00 [pubmed]
PHST- 2019/01/04 06:01 [medline]
PHST- 2018/04/26 00:00 [pmc-release]
AID - S2095-882X(18)30010-0 [pii]
AID - 10.1016/j.cdtm.2018.03.001 [doi]
PST - epublish
SO  - Chronic Dis Transl Med. 2018 Apr 26;4(4):205-210. doi: 
      10.1016/j.cdtm.2018.03.001. eCollection 2018 Dec.