PMID- 30609310
OWN - NLM
STAT- MEDLINE
DCOM- 20200303
LR  - 20200303
IS  - 2042-6984 (Electronic)
IS  - 2042-6976 (Linking)
VI  - 9
IP  - 5
DP  - 2019 May
TI  - Influence of a medialized middle turbinate on olfactory function: a prospective 
      randomized double-blind study.
PG  - 473-478
LID - 10.1002/alr.22279 [doi]
AB  - BACKGROUND: Medialization of the middle turbinate (MT) is an effective technique 
      to prevent recurrent rhinosinusitis but could, in theory, reduce olfactory 
      function by interfering the odorants to reach the olfactory mucosae. We performed 
      a prospective randomized double-blind trial under the hypothesis that olfactory 
      functions would be affected by the status of olfactory mucosae, not by MT 
      medialization. METHODS: In randomly selected sides, the unilateral MT was 
      medialized in 80 patients undergoing bilateral endoscopic sinus surgery for 
      chronic rhinosinusitis. The status of the bilateral olfactory cleft (OC) was 
      photodocumented intraoperatively and categorized into patent (normal or mucosal 
      swelling with discharge) and congested (hypertrophied mucosae or nasal polyps) 
      groups. The butanol threshold test (BTT) was conducted in each nostril before and 
      6 months after the surgery. Correlation between the BTT scores and MT 
      medialization or the OC status was assessed. No smell identification test was 
      conducted side by side, which might limit clinical implications. RESULTS: In 
      total, 46 of 80 patients completed the trial. MT medialization was performed on 
      the left and right side of the nose in 19 and 27 cases, respectively. The 
      intraoperative OC status did not differ between the 2 sides. Perioperative 
      changes in the BTT scores were similar between the medialized and intact MT 
      sides, whereas the preoperative and postoperative BTT scores were higher in the 
      patent OC group than in the congested OC group, regardless of side. CONCLUSION: 
      MT medialization does not impair olfactory function, and OC status is closely 
      related to olfactory function.
CI  - (c) 2019 ARS-AAOA, LLC.
FAU - Kim, Sang-Wook
AU  - Kim SW
AUID- ORCID: 0000-0002-1681-0556
AD  - Department of Otorhinolaryngology, Gyeongsang National University School of 
      Medicine and Gyeongsang National University Hospital, Jinju, Republic of Korea.
AD  - Institute of Health Sciences, Gyeongsang National University, Jinju, Republic of 
      Korea.
FAU - Kim, Rock Bum
AU  - Kim RB
AD  - Regional Cardiocerebrovascular Disease Center, Gyeongsang National University 
      Hospital, Jinju, Republic of Korea.
FAU - Kang, Hyunmo
AU  - Kang H
AD  - Department of Otorhinolaryngology, Gyeongsang National University School of 
      Medicine and Gyeongsang National University Hospital, Jinju, Republic of Korea.
FAU - Cho, Hyun-Jin
AU  - Cho HJ
AD  - Department of Otorhinolaryngology, Gyeongsang National University School of 
      Medicine and Gyeongsang National University Hospital, Jinju, Republic of Korea.
FAU - Joo, Yeon-Hee
AU  - Joo YH
AD  - Department of Otorhinolaryngology, Gyeongsang National University Changwon 
      Hospital, Changwon, Republic of Korea.
FAU - Jeon, Yung Jin
AU  - Jeon YJ
AUID- ORCID: 0000-0002-0285-5534
AD  - Department of Otorhinolaryngology, Gyeongsang National University School of 
      Medicine and Gyeongsang National University Hospital, Jinju, Republic of Korea.
FAU - Jeon, Sea-Yuong
AU  - Jeon SY
AD  - Department of Otorhinolaryngology, Gyeongsang National University School of 
      Medicine and Gyeongsang National University Hospital, Jinju, Republic of Korea.
AD  - Institute of Health Sciences, Gyeongsang National University, Jinju, Republic of 
      Korea.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20190104
PL  - United States
TA  - Int Forum Allergy Rhinol
JT  - International forum of allergy & rhinology
JID - 101550261
SB  - IM
MH  - Adult
MH  - Aged
MH  - Double-Blind Method
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nasal Surgical Procedures
MH  - *Olfactory Mucosa
MH  - *Smell
MH  - Turbinates/*surgery
MH  - Young Adult
OTO - NOTNLM
OT  - olfaction disorders
OT  - olfactory mucosa
OT  - sinusitis
OT  - surgical procedures, operative
OT  - turbinates
EDAT- 2019/01/05 06:00
MHDA- 2020/03/04 06:00
CRDT- 2019/01/05 06:00
PHST- 2018/05/17 00:00 [received]
PHST- 2018/11/29 00:00 [revised]
PHST- 2018/12/16 00:00 [accepted]
PHST- 2019/01/05 06:00 [pubmed]
PHST- 2020/03/04 06:00 [medline]
PHST- 2019/01/05 06:00 [entrez]
AID - 10.1002/alr.22279 [doi]
PST - ppublish
SO  - Int Forum Allergy Rhinol. 2019 May;9(5):473-478. doi: 10.1002/alr.22279. Epub 
      2019 Jan 4.