PMID- 30611242
OWN - NLM
STAT- MEDLINE
DCOM- 20190422
LR  - 20200225
IS  - 1471-2474 (Electronic)
IS  - 1471-2474 (Linking)
VI  - 20
IP  - 1
DP  - 2019 Jan 5
TI  - "Minimal clinically important difference" estimates of 6 commonly-used 
      performance tests in patients with chronic musculoskeletal pain completing a 
      work-related multidisciplinary rehabilitation program.
PG  - 16
LID - 10.1186/s12891-018-2382-2 [doi]
LID - 16
AB  - BACKGROUND: Functional tests are widely used to measure performance in patients 
      with chronic musculoskeletal pain. Our objective was to determine the Minimal 
      Clinically Important Differences (MCID) for the 6-min walk test (6MWT), the Steep 
      Ramp Test (SRT), the 1-min stair climbing test (1MSCT), the sit-to-stand test 
      (STS), the Jamar dynamometer test (JAM) and the lumbar Progressive Isoinertial 
      Lifting Evaluation (PILE) in chronic musculoskeletal pain patients. METHODS: A 
      single-center prospective observational study was conducted in a rehabilitation 
      center. Patients with upper-limb, lower-limb or neck/back lesions were included 
      over a period of 21 months. We used the anchor-based method as a reference 
      method, supplemented by the distribution-based and opinion-based approaches, to 
      determine the MCIDs. RESULTS: 838 chronic musculoskeletal pain patients were 
      included. The estimation method and thelesion location had a significant 
      influence on the results. MCIDs were estimated at +75m and +60m for the 6MWT 
      (lower-limb and neck/back lesions, respectively), +18 steps for the 1MSCT 
      (lower-limb and neck/back lesions) and +6kg for the JAM (upper limb lesions). The 
      anchor-based method could not provide valid estimations for the three other 
      scales, but distribution and opinion-based methods provided rough values of MCIDs 
      for the SRT (+39w to +61w), the STS (-5 sec to -7 sec) and the PILE (+4kg to 
      +7kg). CONCLUSION: The above MCID estimations for the 6MWT, 1MSCT and JAM can be 
      used in chronic musculoskeletal pain patients participating in vocational 
      multidisciplinary rehabilitation programs or in therapeutic trials. The use of 
      specific anchors might give better estimations of MCIDs for the three other 
      scales in future research.
FAU - Benaim, Charles
AU  - Benaim C
AD  - Department of Physical Medicine and Rehabilitation, Orthopaedic Hospital, 
      Lausanne University Hospital, Av Pierre Decker 4, CH-1011, Lausanne, Switzerland. 
      charles.benaim@chuv.ch.
AD  - Institute for Research in Rehabilitation, Clinique Romande de Readaptation, Sion, 
      Switzerland. charles.benaim@chuv.ch.
AD  - Department of Medical Research, Clinique Romande de Readaptation, Sion, 
      Switzerland. charles.benaim@chuv.ch.
FAU - Blaser, Simon
AU  - Blaser S
AD  - Department of Medical Research, Clinique Romande de Readaptation, Sion, 
      Switzerland.
FAU - Leger, Bertrand
AU  - Leger B
AD  - Institute for Research in Rehabilitation, Clinique Romande de Readaptation, Sion, 
      Switzerland.
AD  - Department of Medical Research, Clinique Romande de Readaptation, Sion, 
      Switzerland.
FAU - Vuistiner, Philippe
AU  - Vuistiner P
AD  - Department of Medical Research, Clinique Romande de Readaptation, Sion, 
      Switzerland.
FAU - Luthi, Francois
AU  - Luthi F
AD  - Department of Physical Medicine and Rehabilitation, Orthopaedic Hospital, 
      Lausanne University Hospital, Av Pierre Decker 4, CH-1011, Lausanne, Switzerland.
AD  - Institute for Research in Rehabilitation, Clinique Romande de Readaptation, Sion, 
      Switzerland.
AD  - Department of Medical Research, Clinique Romande de Readaptation, Sion, 
      Switzerland.
AD  - Department for Musculoskeletal Rehabilitation, Clinique Romande de Readaptation, 
      Sion, Switzerland.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Observational Study
DEP - 20190105
PL  - England
TA  - BMC Musculoskelet Disord
JT  - BMC musculoskeletal disorders
JID - 100968565
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Chronic Pain/*diagnosis/physiopathology/rehabilitation
MH  - *Disability Evaluation
MH  - Female
MH  - Health Status
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Muscle Strength Dynamometer
MH  - Musculoskeletal Pain/*diagnosis/physiopathology/rehabilitation
MH  - Pain Measurement
MH  - Predictive Value of Tests
MH  - Prospective Studies
MH  - Treatment Outcome
MH  - Walk Test
MH  - Young Adult
PMC - PMC6320580
OTO - NOTNLM
OT  - Chronic musculoskeletal pain
OT  - Functional tests
OT  - MCID
COIS- ETHICS APPROVAL AND CONSENT TO PARTICIPATE: The study was approved by the local 
      ethics committee (Commission Cantonale Valaisanne d'Ethique Medicale 034/12). All 
      participants signed an informed consent form before enrolment. CONSENT FOR 
      PUBLICATION: Not applicable. COMPETING INTERESTS: All authors read and approved 
      the final manuscript. PUBLISHER'S NOTE: Springer Nature remains neutral with 
      regard to jurisdictional claims in published maps and institutional affiliations.
EDAT- 2019/01/07 06:00
MHDA- 2019/04/23 06:00
PMCR- 2019/01/05
CRDT- 2019/01/07 06:00
PHST- 2017/11/08 00:00 [received]
PHST- 2018/12/18 00:00 [accepted]
PHST- 2019/01/07 06:00 [entrez]
PHST- 2019/01/07 06:00 [pubmed]
PHST- 2019/04/23 06:00 [medline]
PHST- 2019/01/05 00:00 [pmc-release]
AID - 10.1186/s12891-018-2382-2 [pii]
AID - 2382 [pii]
AID - 10.1186/s12891-018-2382-2 [doi]
PST - epublish
SO  - BMC Musculoskelet Disord. 2019 Jan 5;20(1):16. doi: 10.1186/s12891-018-2382-2.