PMID- 30611470
OWN - NLM
STAT- MEDLINE
DCOM- 20190213
LR  - 20190215
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 279
DP  - 2019 May 1
TI  - In vitro bioaccessibility of selenoamino acids from selenium (Se)-enriched 
      Chlorella vulgaris biomass in comparison to selenized yeast; a Se-enriched food 
      supplement; and Se-rich foods.
PG  - 12-19
LID - S0308-8146(18)32091-0 [pii]
LID - 10.1016/j.foodchem.2018.12.004 [doi]
AB  - Selenium (Se) is an indispensable microelement in our diet and health issues 
      resulting from deficiencies are well documented. Se-containing food supplements 
      are available on the market including Se-enriched Chlorella vulgaris 
      (Se-Chlorella) which accumulates Se in the form of Se-amino acids (Se-AAs). 
      Despite its popular uses, data about the bioaccessibility of Se-AAs from 
      Se-Chlorella are completely missing. In the present study, gastrointestinal 
      digestion times were optimized and the in vitro bioaccessibility of Se-AAs in 
      Se-Chlorella, Se-yeast, a commercially available Se-enriched food supplement 
      (Se-supplement) and Se rich foods (Se-foods) were compared. Higher 
      bioaccessibility was found in Se-Chlorella ( approximately 49%) as compared to Se-yeast ( approximately 21%), 
      Se-supplement ( approximately 32%) and Se-foods. The methods used in production of Se-Chlorella 
      biomass were also investigated. We found that disintegration increased 
      bioaccessibility whereas the drying process had no effect. Similarly, temperature 
      treatment by microwave oven also increased bioaccessibility whereas boiling water 
      did not.
CI  - Copyright (c) 2018 Elsevier Ltd. All rights reserved.
FAU - Vu, Dai Long
AU  - Vu DL
AD  - Laboratory of Algal Biotechnology, Centre Algatech, Institute of Microbiology of 
      the Czech Academy of Sciences, Opatovicky mlyn, Novohradska 237, 379 81 Trebon, 
      Czech Republic. Electronic address: longvu1182@gmail.com.
FAU - Saurav, Kumar
AU  - Saurav K
AD  - Laboratory of Algal Biotechnology, Centre Algatech, Institute of Microbiology of 
      the Czech Academy of Sciences, Opatovicky mlyn, Novohradska 237, 379 81 Trebon, 
      Czech Republic.
FAU - Mylenko, Mykola
AU  - Mylenko M
AD  - Laboratory of Algal Biotechnology, Centre Algatech, Institute of Microbiology of 
      the Czech Academy of Sciences, Opatovicky mlyn, Novohradska 237, 379 81 Trebon, 
      Czech Republic.
FAU - Ranglova, Karolina
AU  - Ranglova K
AD  - Laboratory of Algal Biotechnology, Centre Algatech, Institute of Microbiology of 
      the Czech Academy of Sciences, Opatovicky mlyn, Novohradska 237, 379 81 Trebon, 
      Czech Republic.
FAU - Kuta, Jan
AU  - Kuta J
AD  - Laboratory of Algal Biotechnology, Centre Algatech, Institute of Microbiology of 
      the Czech Academy of Sciences, Opatovicky mlyn, Novohradska 237, 379 81 Trebon, 
      Czech Republic; Research Centre for Toxic Compounds in the Environment (RECETOX), 
      Faculty of Science, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic.
FAU - Ewe, Daniela
AU  - Ewe D
AD  - Laboratory of Photosynthesis, Centre Algatech, Institute of Microbiology of the 
      Czech Academy of Sciences, Opatovicky mlyn, Novohradska 237, 379 81 Trebon, Czech 
      Republic.
FAU - Masojidek, Jiri
AU  - Masojidek J
AD  - Laboratory of Algal Biotechnology, Centre Algatech, Institute of Microbiology of 
      the Czech Academy of Sciences, Opatovicky mlyn, Novohradska 237, 379 81 Trebon, 
      Czech Republic.
FAU - Hrouzek, Pavel
AU  - Hrouzek P
AD  - Laboratory of Algal Biotechnology, Centre Algatech, Institute of Microbiology of 
      the Czech Academy of Sciences, Opatovicky mlyn, Novohradska 237, 379 81 Trebon, 
      Czech Republic. Electronic address: hrouzekp@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20181205
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 0CH9049VIS (Selenocysteine)
RN  - 964MRK2PEL (Selenomethionine)
RN  - H6241UJ22B (Selenium)
SB  - IM
MH  - Biomass
MH  - Chlorella vulgaris/*metabolism
MH  - Chromatography, High Pressure Liquid
MH  - Dietary Supplements/analysis
MH  - Food, Fortified/*analysis
MH  - Gas Chromatography-Mass Spectrometry/methods
MH  - Limit of Detection
MH  - Mass Spectrometry/methods
MH  - Saccharomyces cerevisiae/metabolism
MH  - Selenium/*chemistry/metabolism
MH  - Selenocysteine/*analysis/metabolism
MH  - Selenomethionine/*analysis/metabolism
MH  - Temperature
OTO - NOTNLM
OT  - Bioaccessibility
OT  - Gas chromatography atmospheric pressure chemical ionization high resolution mass 
      spectrometry (GC-APCI-HRMS)
OT  - Methanesulfonic acid (PubChem CID: 6395)
OT  - Methylselenocysteine (PubChem CID: 147004)
OT  - Selenium enriched Chlorella vulgaris
OT  - Selenium enriched food supplement
OT  - Selenium rich foods
OT  - Selenized yeast
OT  - Selenoamino acids
OT  - Selenocysteine (PubChem CID: 6326983)
OT  - Selenomethionine (PubChem CID: 15103)
EDAT- 2019/01/07 06:00
MHDA- 2019/02/14 06:00
CRDT- 2019/01/07 06:00
PHST- 2018/10/18 00:00 [received]
PHST- 2018/12/01 00:00 [revised]
PHST- 2018/12/04 00:00 [accepted]
PHST- 2019/01/07 06:00 [entrez]
PHST- 2019/01/07 06:00 [pubmed]
PHST- 2019/02/14 06:00 [medline]
AID - S0308-8146(18)32091-0 [pii]
AID - 10.1016/j.foodchem.2018.12.004 [doi]
PST - ppublish
SO  - Food Chem. 2019 May 1;279:12-19. doi: 10.1016/j.foodchem.2018.12.004. Epub 2018 
      Dec 5.