PMID- 30615141
OWN - NLM
STAT- MEDLINE
DCOM- 20191206
LR  - 20191217
IS  - 1943-7730 (Electronic)
IS  - 0007-5027 (Linking)
VI  - 50
IP  - 3
DP  - 2019 Jul 16
TI  - Automated Requests for Thyroid-Stimulating Hormone and Ferretin Tests in Young 
      Primary Care Patients with Anorexia as an Intervention to Improve Detection of 
      Underlying Conditions.
PG  - 268-272
LID - 10.1093/labmed/lmy076 [doi]
AB  - OBJECTIVE: To improve clinical laboratory contribution to the treatment of 
      primary care patients with anorexia through automated computerized strategies. 
      METHODS: We recorded the number of laboratory requests due to anorexia; the 
      demographic data, laboratory values, and presence of pathological values for the 
      applicable patients. In a prospective study, the laboratory information 
      management system (LIMS) automatically added thyroid-stimulating hormone (TSH) 
      and/or ferritin testing when it was not requested by general practitioners for 
      all primary care patients with anorexia who were younger than 16 years. RESULTS: 
      A total of 3562 patients underwent laboratory testing due to anorexia, of whom 
      47% were younger than 16 years. The tests in which the results most frequently 
      were abnormal were hemoglobin, ferritin, and TSH. TSH results were abnormal in 
      20% of patients younger than 16 years. Through the intervention, we detected 3 
      low ferritin values and 7 cases of pathological TSH levels. CONCLUSIONS: The LIMS 
      required TSH and ferritin testing in young patients even when not requested, 
      potentially avoiding the adverse effects of iron deficiency and thyroid disorders 
      on neurological development and cognition in those patients.
CI  - (c) American Society for Clinical Pathology 2019. All rights reserved. For 
      permissions, please e-mail: journals.permissions@oup.com.
FAU - Salinas, Maria
AU  - Salinas M
AD  - Department of Biochemistry and Molecular Pathology, Universidad Miguel Hernandez, 
      Elche, Spain.
AD  - Clinical Laboratory, Hospital Universitario de San Juan, San Juan de Alicante, 
      Spain.
FAU - Lopez-Garrigos, Maite
AU  - Lopez-Garrigos M
AD  - Clinical Laboratory, Hospital Universitario de San Juan, San Juan de Alicante, 
      Spain.
FAU - Flores, Emilio
AU  - Flores E
AD  - Department of Clinical Medicine, Universidad Miguel Hernandez, San Juan de 
      Alicante, Spain.
AD  - Clinical Laboratory, Hospital Universitario de San Juan, San Juan de Alicante, 
      Spain.
FAU - Leiva-Salinas, Carlos
AU  - Leiva-Salinas C
AD  - Department of Radiology and Medical Imaging, University of Missouri Health Care, 
      Columbia, MO, USA.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - England
TA  - Lab Med
JT  - Laboratory medicine
JID - 0250641
RN  - 9002-71-5 (Thyrotropin)
RN  - 9007-73-2 (Ferritins)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Anorexia/*diagnosis
MH  - Automation/*methods
MH  - Child
MH  - Child, Preschool
MH  - Cross-Sectional Studies
MH  - Diagnostic Tests, Routine/*methods
MH  - Female
MH  - Ferritins/*blood
MH  - Health Information Management/*methods
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Middle Aged
MH  - Primary Health Care/*methods
MH  - Prospective Studies
MH  - Thyrotropin/*blood
MH  - Young Adult
OTO - NOTNLM
OT  - anorexia
OT  - laboratory interventions
OT  - laboratory utilization
OT  - primary care
EDAT- 2019/01/08 06:00
MHDA- 2019/12/18 06:00
CRDT- 2019/01/08 06:00
PHST- 2018/09/14 00:00 [received]
PHST- 2018/11/14 00:00 [accepted]
PHST- 2019/01/08 06:00 [pubmed]
PHST- 2019/12/18 06:00 [medline]
PHST- 2019/01/08 06:00 [entrez]
AID - 5274632 [pii]
AID - 10.1093/labmed/lmy076 [doi]
PST - ppublish
SO  - Lab Med. 2019 Jul 16;50(3):268-272. doi: 10.1093/labmed/lmy076.