PMID- 30625244
OWN - NLM
STAT- MEDLINE
DCOM- 20190306
LR  - 20190306
IS  - 1540-8191 (Electronic)
IS  - 0886-0440 (Linking)
VI  - 34
IP  - 1
DP  - 2019 Jan
TI  - Severe structural deterioration of small aortic bioprostheses treated with 
      valve-in-valve transcatheter aortic valve implantation.
PG  - 7-13
LID - 10.1111/jocs.13976 [doi]
AB  - OBJECTIVES: The aim of this study was to evaluate outcomes of valve-in-valve 
      transcatheter aortic valve implantation (VIV-TAVI) in patients with degenerated 
      small bioprostheses. METHODS: Outcomes of consecutive 27 high-risk patients 
      (logistic EuroSCORE 35.5 +/- 18.5%) with a mean age of 81.0 +/- 5.9 years who 
      underwent VIV-TAVI for degenerated small bioprostheses (19 mm-11.1%; 20 mm-11.1%; 
      21 mm-77.8%) were analyzed. Medtronic CoreValve (n = 11) or CoreValve Evolut-R 
      prostheses (n = 16) were implanted. Follow-up was 3.2 +/- 2.0 years. RESULTS: Early 
      mortality was 11.1%. One patient died intraoperatively due to left ventricle 
      perforation, two others during the in-hospital period as a result of sudden 
      cardiac death and pulmonary embolism. VIV-TAVI was completed in 26 cases 
      (96.3%-success rate). Two patients required pacemaker implantation. Acute kidney 
      injury occurred in two other patients. At discharge, mean transvalvular gradient 
      was 19.2 +/- 9.5 mmHg and in 25.9% of patients mean gradient exceeded 20 mmHg. 
      Overall mortality was 25.9% and mortality from cardiac or unknown causes at 
      18.5%. Ninety percent of survivors were in New York Heart Association (NYHA) 
      class I or II. CONCLUSIONS: Transfemoral VIV-TAVI in patients with small, 
      degenerated bioprostheses appears to be a promising alternative to surgery. 
      Although the vast majority of patients have significant improvement in their NYHA 
      class, the rate of persistent, residual gradients is relatively high and will 
      need to be followed closely with serial echocardiograms.
CI  - (c) 2019 Wiley Periodicals, Inc.
FAU - Stankowski, Tomasz
AU  - Stankowski T
AUID- ORCID: 0000-0003-2054-8199
AD  - Department of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
FAU - Aboul-Hassan, Sleiman Sebastian
AU  - Aboul-Hassan SS
AUID- ORCID: 0000-0003-4544-7466
AD  - Department of Cardiac Surgery, MEDINET Heart Center Ltd., Nowa Sol, Poland.
FAU - Seifi-Zinab, Farzaneh
AU  - Seifi-Zinab F
AD  - Department of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
FAU - Herwig, Volker
AU  - Herwig V
AD  - Department of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
FAU - Kubikova, Miroslava
AU  - Kubikova M
AD  - Department of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
FAU - Harnath, Axel
AU  - Harnath A
AD  - Department of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
FAU - Fritzsche, Dirk
AU  - Fritzsche D
AD  - Department of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
FAU - Perek, Bartlomiej
AU  - Perek B
AD  - Department of Cardiac Surgery and Transplantology, Poznan University of Medical 
      Sciences, Poznan, Poland.
LA  - eng
PT  - Journal Article
DEP - 20190109
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
MH  - Aged, 80 and over
MH  - Aortic Valve/diagnostic imaging/*surgery
MH  - Aortic Valve Stenosis/diagnosis/*surgery
MH  - Bioprosthesis/*adverse effects
MH  - Echocardiography
MH  - Female
MH  - Fluoroscopy
MH  - Follow-Up Studies
MH  - *Heart Valve Prosthesis
MH  - Humans
MH  - Male
MH  - Prosthesis Design
MH  - Reoperation
MH  - Severity of Illness Index
MH  - Transcatheter Aortic Valve Replacement/*methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - outcomes
OT  - reintervention
OT  - structural valve deterioration
OT  - transcatheter aortic valve implantation
EDAT- 2019/01/10 06:00
MHDA- 2019/03/07 06:00
CRDT- 2019/01/10 06:00
PHST- 2019/01/10 06:00 [pubmed]
PHST- 2019/03/07 06:00 [medline]
PHST- 2019/01/10 06:00 [entrez]
AID - 10.1111/jocs.13976 [doi]
PST - ppublish
SO  - J Card Surg. 2019 Jan;34(1):7-13. doi: 10.1111/jocs.13976. Epub 2019 Jan 9.