PMID- 30628561
OWN - NLM
STAT- MEDLINE
DCOM- 20200922
LR  - 20230619
IS  - 1475-2727 (Electronic)
IS  - 1368-9800 (Print)
IS  - 1368-9800 (Linking)
VI  - 23
IP  - 7
DP  - 2020 May
TI  - Vitamin D status of children in Kerala, southern India.
PG  - 1179-1183
LID - 10.1017/S1368980018003622 [doi]
AB  - OBJECTIVE: To study plasma 25-hydroxyvitamin D (25(OH)D) status of children in 
      Kerala, southern India, and its relationship with sociodemographic variables. 
      DESIGN: Cross-sectional observational study. SETTING: Tertiary government 
      hospital. PARTICIPANTS: Children (n 296) with trivial acute illness were 
      enrolled. Sun exposure and Ca and vitamin D intakes (7 d dietary recall) were 
      documented. Serum Ca, P, alkaline phosphatase, plasma 25(OH)D and parathyroid 
      hormone (PTH) were measured. RESULTS: Prevalence of vitamin D deficiency (plasma 
      25(OH)D <30 nmol/l) was 11.1% (median, interquartile range (IQR): 52.6, 38.4-65.6 
      nmol/l). Children who ate fish daily had significantly higher plasma 25(OH)D than 
      those who did not (median, IQR: 52.5, 40.8-68.9 v. 49.1, 36.2-60.7 nmol/l; P = 
      0.02). Those investigated in the months of March-May showed highest 25(OH)D v. 
      those enrolled during other times (median, IQR: 58.7, 45.6-81.4 v. 45.5, 
      35.6-57.4 nmol/l; P <0.001). Plasma 25(OH)D correlated positively with serum P (r 
      = 0.24, P <0.001) and Ca intake (r = 0.16, P 0.03), negatively with age (r = 
      -0.13, P 0.03) and PTH (r = -0.22, P <0.001.). On linear regression, summer 
      season (March-May), lower age, daily fish intake and higher Ca intake were 
      independently associated with plasma 25(OH)D. CONCLUSIONS: Prevalence of vitamin 
      D deficiency is low in Kerala. The natural fish diet of coastal Kerala and the 
      latitude may be protective. Public health policy in India should take account of 
      this geographical diversity.
FAU - Vijayakumar, Madhava
AU  - Vijayakumar M
AD  - Department of Pediatrics, Government Medical College, Kozhikode, Kerala, India.
FAU - Bhatia, Vijayalakshmi
AU  - Bhatia V
AD  - Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical 
      Sciences, Raibarely Road, Lucknow226014, Uttar Pradesh, India.
FAU - George, Biju
AU  - George B
AD  - Department of Community Medicine, Government Medical College, Kozhikode, Kerala, 
      India.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20190110
PL  - England
TA  - Public Health Nutr
JT  - Public health nutrition
JID - 9808463
RN  - 0 (Parathyroid Hormone)
RN  - 0 (Vitamins)
RN  - 1406-16-2 (Vitamin D)
RN  - A288AR3C9H (25-hydroxyvitamin D)
RN  - SY7Q814VUP (Calcium)
SB  - IM
CIN - Public Health Nutr. 2020 May;23(7):1184-1185. doi: 10.1017/S1368980019001265. 
      PMID: 31109389
MH  - Calcium/administration & dosage/blood
MH  - Child
MH  - Child, Preschool
MH  - Cross-Sectional Studies
MH  - Diet
MH  - Female
MH  - Humans
MH  - India/epidemiology
MH  - Infant
MH  - Male
MH  - Nutritional Status
MH  - Parathyroid Hormone/blood
MH  - Seafood
MH  - Seasons
MH  - Sunlight
MH  - Vitamin D/administration & dosage/analogs & derivatives/*blood
MH  - Vitamin D Deficiency/blood/drug therapy/*epidemiology
MH  - Vitamins/administration & dosage/blood
PMC - PMC10200497
OTO - NOTNLM
OT  - 25-Hydroxyvitamin D
OT  - Fish
OT  - Latitude
OT  - Rickets
OT  - Sun
EDAT- 2019/01/11 06:00
MHDA- 2020/09/23 06:00
PMCR- 2020/05/01
CRDT- 2019/01/11 06:00
PHST- 2019/01/11 06:00 [pubmed]
PHST- 2020/09/23 06:00 [medline]
PHST- 2019/01/11 06:00 [entrez]
PHST- 2020/05/01 00:00 [pmc-release]
AID - S1368980018003622 [pii]
AID - 10.1017/S1368980018003622 [doi]
PST - ppublish
SO  - Public Health Nutr. 2020 May;23(7):1179-1183. doi: 10.1017/S1368980018003622. 
      Epub 2019 Jan 10.