PMID- 30631360 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20231005 IS - 1687-8728 (Print) IS - 1687-8736 (Electronic) IS - 1687-8728 (Linking) VI - 2018 DP - 2018 TI - An In Situ Evaluation of the Protective Effect of Nano Eggshell/Titanium Dioxide against Erosive Acids. PG - 4216415 LID - 10.1155/2018/4216415 [doi] LID - 4216415 AB - OBJECTIVES: Enamel erosion caused by high consumption of acidic drinks poses a significant public health concern. This study was aimed to determine the protective effect of eggshell-titanium dioxide composite (EB@TiO(2)) against erosive acids on tooth enamel. METHODS: Twenty prepared bovine tooth enamel specimens were randomly assigned to 5 sample groups (n=4): (1) unexposed tooth enamel; (2) exposed tooth enamel + HCI; (3) exposed tooth enamel + HCI + Colgate toothpaste; (4) exposed tooth enamel + HCI + Sensodyne toothpaste; and (5) exposed tooth enamel + HCI + EB@TiO(2). The mean roughness value (R (rms)) of the exposed and unexposed tooth was measured with atomic force microscope (AFM). Scanning electron microscope (SEM) and Raman spectroscopy techniques were used to evaluate the surface morphology and changes. ANOVA was used to analyze the mean square roughness (R (rms)) values for all specimens. Bonferonni correction was used to identify the mean differences among the 5 groups (alpha=0.05). The R (rms) values measured for the unexposed and exposed specimens in HCI alone were statistically significant (P < 0.05). RESULTS: No significant differences were found for the unexposed and exposed specimens in HCI + toothpaste and EB@TiO(2). The tooth enamel specimens exposed to HCI + Sensodyne had the highest R (rms) values, while specimens exposed to HCI + EB@TiO(2) had the lowest R (rms) values. CONCLUSIONS: This study confirms that the investigated toothpaste provides protection against acidic substances. The study results further suggests that EB@TiO(2) could be used to provide enhanced protection for tooth enamel. FAU - Onwubu, Stanley Chibuzor AU - Onwubu SC AUID- ORCID: 0000-0002-4499-1534 AD - Dental Sciences, Durban University of Technology (DUT), Durban, South Africa. FAU - Mdluli, Phumlane Selby AU - Mdluli PS AD - Chemistry, Durban University of Technology (DUT), Durban, South Africa. FAU - Singh, Shenuka AU - Singh S AUID- ORCID: 0000-0003-4842-602X AD - Discipline of Dentistry, University of KwaZulu-Natal (UKZN), Durban, South Africa. FAU - Nyembe, Sanele AU - Nyembe S AUID- ORCID: 0000-0002-2848-0806 AD - DST/Mintek Nanotechnology Innovation Centre, Advanced Materials Division, Mintek, Private Bag X3015, Randburg, Johannesburg 2125, South Africa. FAU - Thakur, Rookmoney AU - Thakur R AD - Dental Sciences, Durban University of Technology (DUT), Durban, South Africa. LA - eng PT - Journal Article DEP - 20181202 PL - Egypt TA - Int J Dent JT - International journal of dentistry JID - 101524183 EIN - Int J Dent. 2019 Mar 10;2019:7209168. PMID: 30984264 PMC - PMC6304922 EDAT- 2019/01/12 06:00 MHDA- 2019/01/12 06:01 PMCR- 2018/12/02 CRDT- 2019/01/12 06:00 PHST- 2018/08/18 00:00 [received] PHST- 2018/10/19 00:00 [revised] PHST- 2018/11/07 00:00 [accepted] PHST- 2019/01/12 06:00 [entrez] PHST- 2019/01/12 06:00 [pubmed] PHST- 2019/01/12 06:01 [medline] PHST- 2018/12/02 00:00 [pmc-release] AID - 10.1155/2018/4216415 [doi] PST - epublish SO - Int J Dent. 2018 Dec 2;2018:4216415. doi: 10.1155/2018/4216415. eCollection 2018.