PMID- 30633941
OWN - NLM
STAT- MEDLINE
DCOM- 20190429
LR  - 20190429
IS  - 1097-6787 (Electronic)
IS  - 0190-9622 (Linking)
VI  - 80
IP  - 5
DP  - 2019 May
TI  - Severity of disease and quality of life in parents of children with alopecia 
      areata, totalis, and universalis: A prospective, cross-sectional study.
PG  - 1389-1394
LID - S0190-9622(19)30057-X [pii]
LID - 10.1016/j.jaad.2018.12.051 [doi]
AB  - BACKGROUND: Caregiver-oriented quality of life (QoL) research in alopecia areata 
      is limited. No study has used a parent-tailored survey to examine the 
      relationship between QoL and severity of alopecia as measured by Severity of 
      Alopecia Tool (SALT) scores. OBJECTIVES: This is a prospective study that 
      describes QoL in parents of pediatric patients with all subtypes of alopecia 
      areata and investigates the relationship between QoL and severity of disease, 
      duration of disease, and age of patients. METHODS: Pediatric patients and their 
      parents were invited to participate during clinic visits. Participating parents 
      completed the Quality of Life in a Child's Chronic Disease Questionnaire (QLCCDQ) 
      and the Family Dermatology Life Quality Index (FDLQI). A subset of children 
      completed the Children's Dermatologic Life Quality Index (CDLQI). SALT scores at 
      time of survey completion were recorded. RESULTS: In total, 153 patients were 
      included. Significant mild-to-moderate negative correlations were found between 
      SALT scores and FDLQI scores, QLCCDQ scores, and QLCCDQ emotional domain scores. 
      Age of child correlated negatively with QLCCDQ scores but not FDLQI scores. No 
      significant correlation was found between duration of disease and FDLQI scores, 
      QLCCDQ scores, or QLCCDQ emotional domain scores. LIMITATIONS: This study is 
      limited by its small sample size and cross-sectional design. CONCLUSIONS: 
      Impaired parent QoL might be associated with increasing severity of disease and 
      age of affected child but not duration of disease. Providers should tailor 
      counseling accordingly and help parents set realistic expectations for long-term 
      experience with the disease.
CI  - Copyright (c) 2019 American Academy of Dermatology, Inc. Published by Elsevier Inc. 
      All rights reserved.
FAU - Putterman, Elana
AU  - Putterman E
AD  - Division of Pediatrics, Section of Dermatology, The Children's Hospital of 
      Philadelphia, Philadelphia, Pennsylvania.
FAU - Patel, Deepa P
AU  - Patel DP
AD  - Division of Pediatrics, Section of Dermatology, The Children's Hospital of 
      Philadelphia, Philadelphia, Pennsylvania.
FAU - Andrade, Gabriela
AU  - Andrade G
AD  - Division of Pediatrics, Section of Dermatology, The Children's Hospital of 
      Philadelphia, Philadelphia, Pennsylvania.
FAU - Harfmann, Katya L
AU  - Harfmann KL
AD  - Department of Dermatology, Nationwide Children's Hospital, Columbus, Ohio.
FAU - Hogeling, Marcia
AU  - Hogeling M
AD  - Division of Dermatology, University of California Los Angeles, Los Angeles, 
      California.
FAU - Cheng, Carol E
AU  - Cheng CE
AD  - Division of Dermatology, University of California Los Angeles, Los Angeles, 
      California.
FAU - Goh, Carolyn
AU  - Goh C
AD  - Division of Dermatology, University of California Los Angeles, Los Angeles, 
      California.
FAU - Rogers, Rachel S
AU  - Rogers RS
AD  - Biostatistics and Data Management, The Children's Hospital of Philadelphia, 
      Philadelphia, Pennsylvania.
FAU - Castelo-Soccio, Leslie
AU  - Castelo-Soccio L
AD  - Division of Pediatrics, Section of Dermatology, The Children's Hospital of 
      Philadelphia, Philadelphia, Pennsylvania; University of Pennsylvania Perelman 
      School of Medicine, Philadelphia, Pennsylvania. Electronic address: 
      castelosocciol@email.chop.edu.
LA  - eng
PT  - Journal Article
DEP - 20190108
PL  - United States
TA  - J Am Acad Dermatol
JT  - Journal of the American Academy of Dermatology
JID - 7907132
RN  - Alopecia universalis
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Alopecia/*psychology
MH  - Alopecia Areata/*psychology
MH  - Child
MH  - Child, Preschool
MH  - Cross-Sectional Studies
MH  - Emotions
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Parents/*psychology
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
MH  - Time Factors
MH  - Young Adult
OTO - NOTNLM
OT  - Severity of Alopecia Tool
OT  - alopecia areata
OT  - alopecia totalis
OT  - alopecia universalis
OT  - hair loss
OT  - quality of life
EDAT- 2019/01/12 06:00
MHDA- 2019/04/30 06:00
CRDT- 2019/01/12 06:00
PHST- 2018/09/13 00:00 [received]
PHST- 2018/11/29 00:00 [revised]
PHST- 2018/12/27 00:00 [accepted]
PHST- 2019/01/12 06:00 [pubmed]
PHST- 2019/04/30 06:00 [medline]
PHST- 2019/01/12 06:00 [entrez]
AID - S0190-9622(19)30057-X [pii]
AID - 10.1016/j.jaad.2018.12.051 [doi]
PST - ppublish
SO  - J Am Acad Dermatol. 2019 May;80(5):1389-1394. doi: 10.1016/j.jaad.2018.12.051. 
      Epub 2019 Jan 8.