PMID- 30635749
OWN - NLM
STAT- MEDLINE
DCOM- 20190520
LR  - 20200930
IS  - 1573-3017 (Electronic)
IS  - 0963-9292 (Linking)
VI  - 28
IP  - 1
DP  - 2019 Jan
TI  - Exposure to herbicide linuron results in alterations in hematological profile and 
      stress biomarkers of common carp (Cyprinus carpio).
PG  - 69-75
LID - 10.1007/s10646-018-2000-y [doi]
AB  - Phenylurea herbicides such as linuron are commonly applied in agriculture. Common 
      carp juveniles were subjected to 31.5 microg/L of linuron for 14 days, and then to 30 
      days of purification. Peripheral blood was sampled after 1, 3, 7 and 14 days of 
      exposure and 7, 14 and 30 days of purification and hematological parameters were 
      evaluated: erythrocyte (RBCc) and leukocyte (WBCc) counts, hematocrit (Ht), 
      hemoglobin concentration (Hb), mean cell volume (MCV), mean corpuscular 
      hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and 
      differential leukocyte count. For evaluation of cortisol and catecholamine 
      concentrations blood was sampled after 3, 6 and 12 h, after 1, 3 and 14 days of 
      exposure, and after 30 days of purification. Linuron caused mainly transient 
      increase in RBCc, Ht and MCV values and increase in WBCc and percentage of 
      juvenile neutrophils. The herbicide caused persistant increase of cortisol and 
      catecholamine concentrations. The results indicate that exposure to low 
      concentration of linuron induced a stress response in common carp.
FAU - Lutnicka, Hanna
AU  - Lutnicka H
AD  - Institute of Veterinary Science, University Centre of Veterinary Medicine, 
      University of Agriculture in Krakow, Mickiewicza 24/28 Street, Krakow, 30-059, 
      Poland.
FAU - Bojarski, Bartosz
AU  - Bojarski B
AD  - Department of Animal Physiology, Institute of Biology, Siedlce University of 
      Natural Sciences and Humanities, Prusa 14 Street, Siedlce, 08-110, Poland. 
      bbojarski@o2.pl.
FAU - Witeska, Malgorzata
AU  - Witeska M
AD  - Department of Animal Physiology, Institute of Biology, Siedlce University of 
      Natural Sciences and Humanities, Prusa 14 Street, Siedlce, 08-110, Poland.
FAU - Tombarkiewicz, Barbara
AU  - Tombarkiewicz B
AD  - Department of Veterinary Science, Animal Reproduction and Welfare, University of 
      Agriculture in Krakow, Mickiewicza 24/28 Street, Krakow, 30-059, Poland.
FAU - Formicki, Grzegorz
AU  - Formicki G
AD  - Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical 
      University of Krakow, Podbrzezie 3 Street, Krakow, 31-054, Poland.
LA  - eng
GR  - N N304 279440/National Science Center, Poland/
GR  - ---/University Centre of Veterinary Medicine UJ-UA in Krakow/
GR  - DS 3263/ZWRiDZ/Department of Veterinary Science, Animal Reproduction and Welfare/
PT  - Journal Article
DEP - 20190111
PL  - United States
TA  - Ecotoxicology
JT  - Ecotoxicology (London, England)
JID - 9885956
RN  - 0 (Biomarkers)
RN  - 0 (Catecholamines)
RN  - 0 (Herbicides)
RN  - 0 (Water Pollutants, Chemical)
RN  - 01XP1SU59O (Linuron)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Animals
MH  - Biomarkers/blood
MH  - Carps/blood/*metabolism
MH  - Catecholamines/blood
MH  - Hematologic Tests/veterinary
MH  - Herbicides/*toxicity
MH  - Hydrocortisone/blood
MH  - Linuron/*toxicity
MH  - Random Allocation
MH  - Stress, Physiological
MH  - Water Pollutants, Chemical/*toxicity
OTO - NOTNLM
OT  - Blood
OT  - Catecholamines
OT  - Cortisol
OT  - Fish
OT  - Pesticide
EDAT- 2019/01/13 06:00
MHDA- 2019/05/21 06:00
CRDT- 2019/01/13 06:00
PHST- 2018/11/03 00:00 [accepted]
PHST- 2019/01/13 06:00 [pubmed]
PHST- 2019/05/21 06:00 [medline]
PHST- 2019/01/13 06:00 [entrez]
AID - 10.1007/s10646-018-2000-y [pii]
AID - 10.1007/s10646-018-2000-y [doi]
PST - ppublish
SO  - Ecotoxicology. 2019 Jan;28(1):69-75. doi: 10.1007/s10646-018-2000-y. Epub 2019 
      Jan 11.