PMID- 30641723
OWN - NLM
STAT- MEDLINE
DCOM- 20190513
LR  - 20190513
IS  - 1878-0334 (Electronic)
IS  - 1871-4021 (Linking)
VI  - 13
IP  - 1
DP  - 2019 Jan-Feb
TI  - Correlation between basal metabolic rate, visceral fat and insulin resistance 
      among type 2 diabetes mellitus with peripheral neuropathy.
PG  - 344-348
LID - S1871-4021(18)30405-3 [pii]
LID - 10.1016/j.dsx.2018.10.005 [doi]
AB  - BACKGROUND: Basal Metabolic Rate (BMR) means the amount of energy utilized by 
      body in physical and psychological resting rate, after a night sleep, awake 
      without any previous physical activity post meal (10 h after last meal) & neutral 
      environment. In people with type 2 diabetes mellitus (T2DM) there is an increase 
      in BMR which is said to be associated with the level of glycaemic control. So, 
      the objective of the study was to find out the correlation between BMR, Insulin 
      resistance and Visceral fat in T2DM with peripheral neuropathy. MATERIALS & 
      METHODS: A total of 50 participants with T2DM with peripheral neuropathy were 
      included. Age group of 30-75 years were selected for the study. Participants with 
      a known history of neurological disease, locomotor disability, and pregnancy were 
      excluded from the study. Demographic details of the participants like duration of 
      diabetes mellitus, age, Fasting Blood Glucose, Fasting Insulin, HOMA-IR, Glycated 
      Haemoglobin (HBA1c), Neuropathy and Blood pressure values were noted. We measured 
      Basal Metabolic Rate (BMR) by using Mifflin-St Jeor predictive equation in T2DM 
      with peripheral neuropathy. RESULTS: The mean age of the participants is 
      60.16 +/- 10.62. The mean duration of T2DM 13.44 +/- 11.92. In the present study we 
      found a statistical significant correlation between BMR and HOMA IR (r = 0.913*; 
      p = 0.000), BMR & Fasting blood sugar (FBS) (r = 0.281*; p = 0.048), BMR and 
      Visceral fat (VF) (r = 0.332*; p = 0.018). CONCLUSION: Basal metabolic rate is 
      correlated to Homa-IR, visceral fat, fasting blood sugar and musculoskeletal mass 
      among T2DM with peripheral neuropathy.
CI  - Copyright (c) 2018 Diabetes India. Published by Elsevier Ltd. All rights reserved.
FAU - Sampath Kumar, A
AU  - Sampath Kumar A
AD  - Department of Physiotherapy, School of Allied Health Sciences, Manipal Academy of 
      Higher Education, Manipal, Karnataka, 576104, India. Electronic address: 
      sampathkpt@gmail.com.
FAU - Arun Maiya, G
AU  - Arun Maiya G
AD  - Department of Physiotherapy, School of Allied Health Sciences, Manipal Academy of 
      Higher Education, Manipal, Karnataka, 576104, India. Electronic address: 
      arun.maiya.g@gmail.com.
FAU - Shastry, B A
AU  - Shastry BA
AD  - Department of General Medicine, Kasturba Medical College, Manipal, 576104, India. 
      Electronic address: shastryba@yahoo.co.in.
FAU - Vaishali, K
AU  - Vaishali K
AD  - Department of Physiotherapy, School of Allied Health Sciences, Manipal Academy of 
      Higher Education, Udupi, Karnataka, 576104, India. Electronic address: 
      vaishali.kh@manipal.edu.
FAU - Maiya, Shubha
AU  - Maiya S
AD  - Department of Physiotherapy, School of Allied Health Sciences, Manipal Academy of 
      Higher Education, Manipal, Karnataka, 576104, India. Electronic address: 
      s.gmaiya@gmail.com.
FAU - Umakanth, Shashikiran
AU  - Umakanth S
AD  - Department of General Medicine, Dr. T.M.A Pai Hospital, Melaka Manipal Medical 
      College, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India. 
      Electronic address: shashikiran.u@manipal.edu.
LA  - eng
PT  - Journal Article
DEP - 20181010
PL  - Netherlands
TA  - Diabetes Metab Syndr
JT  - Diabetes & metabolic syndrome
JID - 101462250
RN  - 0 (Biomarkers)
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Basal Metabolism
MH  - Biomarkers/*metabolism
MH  - Body Mass Index
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - *Insulin Resistance
MH  - Intra-Abdominal Fat/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - Peripheral Nervous System Diseases/etiology/metabolism/*pathology
MH  - Prognosis
OTO - NOTNLM
OT  - Basal energy expenditure
OT  - Bioelectrical impedance analysis
OT  - Insulin resistance
OT  - Peripheral neuropathy
OT  - Predictive equation
OT  - Type 2 diabetes mellitus
EDAT- 2019/01/16 06:00
MHDA- 2019/05/14 06:00
CRDT- 2019/01/16 06:00
PHST- 2018/08/27 00:00 [received]
PHST- 2018/10/09 00:00 [accepted]
PHST- 2019/01/16 06:00 [entrez]
PHST- 2019/01/16 06:00 [pubmed]
PHST- 2019/05/14 06:00 [medline]
AID - S1871-4021(18)30405-3 [pii]
AID - 10.1016/j.dsx.2018.10.005 [doi]
PST - ppublish
SO  - Diabetes Metab Syndr. 2019 Jan-Feb;13(1):344-348. doi: 10.1016/j.dsx.2018.10.005. 
      Epub 2018 Oct 10.