PMID- 30641757
OWN - NLM
STAT- MEDLINE
DCOM- 20190426
LR  - 20190426
IS  - 1878-0334 (Electronic)
IS  - 1871-4021 (Linking)
VI  - 13
IP  - 1
DP  - 2019 Jan-Feb
TI  - Non-HDL cholesterol predictive factor of type 2 diabetes in the city of Tlemcen.
PG  - 518-521
LID - S1871-4021(18)30461-2 [pii]
LID - 10.1016/j.dsx.2018.11.021 [doi]
AB  - BACKGROUND: type 2 diabetes mellitus (T2DM) is associated with disorders of 
      lipoprotein metabolism mixed dyslipidemia. The purpose of this study is to verify 
      whether non high density lipoprotein cholesterol (non-HDL-C) can contribute to 
      the development of T2DM in a population in the extreme western Algeria. METHODS: 
      The study was conducted in Tlemcen region on a sample of 1852 subjects,1059 with 
      T2DM and 793 controls, these were evaluated for biochemical parameters, measured 
      using standard enzyme procedures (SFBC or IFCC recommendations) on the Beckman 
      CX7((R)) PLC (Beckman-Coulter((R)), NY, USA). All the information related to the 
      disease were collected from the patients and recorded using predesigned 
      questionnaire. RESULTS: The logistic model retained, the two levels of non-HDL-C: 
      130 mg/dl < non-HDL-C</=160 mg/dl (OR = 0,69; 95% CI = 0,49-0,97, P = 0,033) and 
      non-HDL-C>190 mg/dl (OR = 2,22; 95% CI = 1,31-3,76, P = 0,003), inbreeding 
      (OR = 1,71; 95% CI = 1,44-2,04, P = 0,000) and the two age groups 60-70 years 
      (OR = 2,14; 95% CI = 1,47-3,1, P << 0,001) and 70 years and over (OR = 2,26; 95% 
      CI = 1,51-3,38, P << 0,001). CONCLUSIONS: The logistic model shows that non-HDL-C 
      contributes to the development of type 2 diabetes in our population.
CI  - Copyright (c) 2018 Diabetes India. Published by Elsevier Ltd. All rights reserved.
FAU - Dali-Sahi, Majda
AU  - Dali-Sahi M
AD  - Department of Biology, Analytical Chemistry and Electrochemistry Laoboratory, 
      University of Tlemcen, 13000, Algeria.
FAU - Kachekouche, Youssouf
AU  - Kachekouche Y
AD  - Department of Biology, Analytical Chemistry and Electrochemistry Laoboratory, 
      University of Tlemcen, 13000, Algeria. Electronic address: 
      youcef.kache13@gmail.com.
FAU - Dennouni-Medjati, Nouria
AU  - Dennouni-Medjati N
AD  - Department of Biology, Analytical Chemistry and Electrochemistry Laoboratory, 
      University of Tlemcen, 13000, Algeria.
FAU - Nafuye, Gilbert
AU  - Nafuye G
AD  - Department of Biology, Analytical Chemistry and Electrochemistry Laoboratory, 
      University of Tlemcen, 13000, Algeria.
LA  - eng
PT  - Journal Article
DEP - 20181105
PL  - Netherlands
TA  - Diabetes Metab Syndr
JT  - Diabetes & metabolic syndrome
JID - 101462250
RN  - 0 (Cholesterol, HDL)
RN  - 97C5T2UQ7J (Cholesterol)
SB  - IM
MH  - Aged
MH  - Algeria/epidemiology
MH  - Case-Control Studies
MH  - Cholesterol/*blood
MH  - Cholesterol, HDL
MH  - Diabetes Mellitus, Type 2/*blood/diagnosis/*epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
OTO - NOTNLM
OT  - Logistic model
OT  - Non-HDL-C
OT  - Type 2 diabetes mellitus
OT  - Western Algeria
EDAT- 2019/01/16 06:00
MHDA- 2019/04/27 06:00
CRDT- 2019/01/16 06:00
PHST- 2018/10/01 00:00 [received]
PHST- 2018/11/02 00:00 [accepted]
PHST- 2019/01/16 06:00 [entrez]
PHST- 2019/01/16 06:00 [pubmed]
PHST- 2019/04/27 06:00 [medline]
AID - S1871-4021(18)30461-2 [pii]
AID - 10.1016/j.dsx.2018.11.021 [doi]
PST - ppublish
SO  - Diabetes Metab Syndr. 2019 Jan-Feb;13(1):518-521. doi: 10.1016/j.dsx.2018.11.021. 
      Epub 2018 Nov 5.