PMID- 30641801 OWN - NLM STAT- MEDLINE DCOM- 20190425 LR - 20190425 IS - 1878-0334 (Electronic) IS - 1871-4021 (Linking) VI - 13 IP - 1 DP - 2019 Jan-Feb TI - Dyslipidaemia as a risk factor for erectile dysfunction in type 2 diabetes mellitus patients. PG - 748-753 LID - S1871-4021(18)30526-5 [pii] LID - 10.1016/j.dsx.2018.11.052 [doi] AB - BACKGROUND: Despite epidemiological studies worldwide have documented erectile dysfunction (ED) as a major complication of type 2 diabetes Mellitus (T2DM) in men, only limited research reported on determinants of ED in this population. The study aimed at examining the association of ED with dyslipidaemia in T2DM patients. METHODS: The study enrolled 813 consecutive eligible adult male T2DM patients attending the endocrinology departments of a tertiary teaching hospital in Bangladesh. Sexual function was assessed using modified International Index of Erectile Function (IIEF) in face-to-face interview and collected along with sociodemographic information. Diabetes and lipid profile and treatment history were collected from patient's treatment records. Association of ED with dyslipidaemia was assessed using multivariable logistic regression adjusting for potential confounders. RESULT: Prevalence of ED among the T2DM patients was very high (72.7%), of which around half had moderated-to-severe ED. Odds of having dyslipidaemia among T2DM patients with ED is 2.3 times higher than those without. The odds increased by approximately 3 fold for an abnormal High Density Lipoprotein level and by 2.7 fold for abnormal Low Density Lipoprotein. CONCLUSION: Dyslipidaemia was associated with increased ED risk among T2DM. Abnormal lipoprotein level particularly were found to pose greater risk. CI - Copyright (c) 2018 Diabetes India. Published by Elsevier Ltd. All rights reserved. FAU - Azad, Abul Kalam AU - Azad AK AD - Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. FAU - Setunge, Sumudu AU - Setunge S AD - Faculty of Medicine Nursing and Health Sciences, Monash University, Australia. FAU - Selim, Shahjada AU - Selim S AD - Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. FAU - Chowdhury, Shahabul Huda AU - Chowdhury SH AD - Government Employee Hospital, Dhaka, Bangladesh. FAU - Rahaman, Mohammad Ferdousur AU - Rahaman MF AD - Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. FAU - Chowdhury, Md Abdul Jalil AU - Chowdhury MAJ AD - Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. FAU - de Courten, Barbora AU - de Courten B AD - Schools of Public Health and Preventive Medicine, Monash University, Australia. FAU - Ilic, Dragan AU - Ilic D AD - Schools of Public Health and Preventive Medicine, Monash University, Australia. FAU - Karim, Md Nazmul AU - Karim MN AD - Schools of Public Health and Preventive Medicine, Monash University, Australia. Electronic address: nazmul.karim@monash.edu. LA - eng PT - Journal Article DEP - 20181130 PL - Netherlands TA - Diabetes Metab Syndr JT - Diabetes & metabolic syndrome JID - 101462250 SB - IM MH - Adult MH - Diabetes Mellitus, Type 2/blood/*diagnosis/*epidemiology MH - Dyslipidemias/blood/*diagnosis/*epidemiology MH - Erectile Dysfunction/blood/*diagnosis/*epidemiology MH - Humans MH - Male MH - Middle Aged MH - Risk Factors MH - Young Adult OTO - NOTNLM OT - Diabetic complication OT - Dyslipidaemia OT - Erectile dysfunction OT - Lipoprotein OT - Sexual function OT - Type 2 diabetes mellitus EDAT- 2019/01/16 06:00 MHDA- 2019/04/26 06:00 CRDT- 2019/01/16 06:00 PHST- 2018/11/05 00:00 [received] PHST- 2018/11/29 00:00 [accepted] PHST- 2019/01/16 06:00 [entrez] PHST- 2019/01/16 06:00 [pubmed] PHST- 2019/04/26 06:00 [medline] AID - S1871-4021(18)30526-5 [pii] AID - 10.1016/j.dsx.2018.11.052 [doi] PST - ppublish SO - Diabetes Metab Syndr. 2019 Jan-Feb;13(1):748-753. doi: 10.1016/j.dsx.2018.11.052. Epub 2018 Nov 30.