PMID- 30643074
OWN - NLM
STAT- MEDLINE
DCOM- 20190213
LR  - 20190215
IS  - 1672-7347 (Print)
IS  - 1672-7347 (Linking)
VI  - 43
IP  - 11
DP  - 2018 Nov 28
TI  - Coexistence of systemic sclerosis and ankylosing spondylitis: A case report and 
      literature review.
PG  - 1263-1265
LID - 10.11817/j.issn.1672-7347.2018.11.016 [doi]
AB  - Systemic sclerosis (SSc) is an autoimmune disease characterized by thickening of 
      the skin and organ fibrosis. Ankylosing spondylitis (AS) is a type of arthritis 
      with long-term inflammation of the axial joints. Previous studies presented 5 
      cases of concomitant AS and SSc. However, there was only 1 patient of those 5 
      cases complaining of muscle weakness while all patients had approximately normal 
      creatine kinase (CK). Here we reported a young male who met the criteria for SSc 
      and AS while showing significantly elevated CK. Human leukocyte antigen (HLA) 
      typing results indicated the genetic susceptibility to these two diseases. The 
      patient was prescribed prednisone (30 mg/d) and cyclophosphamide. After 2 months, 
      the patient's skin became soft with normal CK.
FAU - Hu, Shulin
AU  - Hu S
AD  - Department of Rheumatology and Immunology, Xiangya Hospital, Central South 
      University; Institute of Rheumatology and Immunology, Central South University, 
      Changsha 410008, China.
FAU - Zuo, Xiaoxia
AU  - Zuo X
AD  - Department of Rheumatology and Immunology, Xiangya Hospital, Central South 
      University; Institute of Rheumatology and Immunology, Central South University, 
      Changsha 410008, China.
FAU - Li, Yisha
AU  - Li Y
AD  - Department of Rheumatology and Immunology, Xiangya Hospital, Central South 
      University; Institute of Rheumatology and Immunology, Central South University, 
      Changsha 410008, China.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - China
TA  - Zhong Nan Da Xue Xue Bao Yi Xue Ban
JT  - Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. 
      Medical sciences
JID - 101230586
RN  - 0 (Anti-Inflammatory Agents)
RN  - 0 (Immunosuppressive Agents)
RN  - 8N3DW7272P (Cyclophosphamide)
RN  - EC 2.7.3.2 (Creatine Kinase)
RN  - VB0R961HZT (Prednisone)
SB  - IM
MH  - Anti-Inflammatory Agents/therapeutic use
MH  - Creatine Kinase/blood
MH  - Cyclophosphamide/therapeutic use
MH  - Genetic Predisposition to Disease
MH  - Histocompatibility Testing
MH  - Humans
MH  - Immunosuppressive Agents/therapeutic use
MH  - Male
MH  - Prednisone/therapeutic use
MH  - *Scleroderma, Systemic/complications/drug therapy/genetics
MH  - *Spondylitis, Ankylosing/complications/drug therapy/genetics
MH  - Treatment Outcome
EDAT- 2019/01/16 06:00
MHDA- 2019/02/14 06:00
CRDT- 2019/01/16 06:00
PHST- 2019/01/16 06:00 [entrez]
PHST- 2019/01/16 06:00 [pubmed]
PHST- 2019/02/14 06:00 [medline]
AID - 10.11817/j.issn.1672-7347.2018.11.016 [doi]
PST - ppublish
SO  - Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Nov 28;43(11):1263-1265. doi: 
      10.11817/j.issn.1672-7347.2018.11.016.