PMID- 30650038
OWN - NLM
STAT- MEDLINE
DCOM- 20190412
LR  - 20190412
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 36
IP  - 2
DP  - 2019 Feb
TI  - Novel sequential separation and determination of a quaternary mixture of 
      fungicides by using an automatic fluorimetric optosensor.
PG  - 278-288
LID - 10.1080/19440049.2018.1564372 [doi]
AB  - A versatile flow-through multi-optosensor is proposed for the separation and 
      spectrofluorimetric determination of mixtures of four widely used pesticides: 
      carbendazim, thiabendazole, carbaryl and o-phenylphenol at microg g(-1) levels in 
      fruits. The flow system is based on the online pre-concentration and separation 
      of the pesticides on a solid sensing microzone, followed by the sequential 
      measurement of their native fluorescence. The separation of the pesticides takes 
      place on a solid support located in the same flow cell, on which analytes are 
      temporarily immobilized and separated from the matrix due to their different 
      retention/desorption kinetics when they interact with the C(18) silica gel 
      microbeads. Suitable analytical parameters were obtained for the selected 
      analytes, with method detection and quantification limits ranging between 0.1-0.5 
      and 0.2-1.6 microg g(-1), respectively. These values comply with the maximum residue 
      limits (MRLs) established by the Codex Alimentarius for these commodities; in 
      addition, carbendazim, thiabendazole and ortho-phenylphenol comply with the MRLs 
      of The European Union. The developed method was applied to the analysis of citrus 
      fruits by performing recovery studies. Recoveries between 85% and 115% were 
      obtained in all cases, and the results were confirmed by a liquid 
      chromatography-mass spectrometry reference method.
FAU - Delgado-Blanca, I
AU  - Delgado-Blanca I
AD  - a Department of Physical and Analytical Chemistry, Faculty of Experimental 
      Sciences , University of Jaen , Jaen , Spain.
FAU - Ruiz-Medina, A
AU  - Ruiz-Medina A
AUID- ORCID: 0000-0002-1632-9092
AD  - a Department of Physical and Analytical Chemistry, Faculty of Experimental 
      Sciences , University of Jaen , Jaen , Spain.
FAU - Ortega-Barrales, P
AU  - Ortega-Barrales P
AUID- ORCID: 0000-0003-2255-6643
AD  - a Department of Physical and Analytical Chemistry, Faculty of Experimental 
      Sciences , University of Jaen , Jaen , Spain.
LA  - eng
PT  - Journal Article
DEP - 20190116
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Fungicides, Industrial)
SB  - IM
MH  - *Automation
MH  - Chromatography, Liquid
MH  - *Fluorometry
MH  - Fungicides, Industrial/*analysis
MH  - Mass Spectrometry
OTO - NOTNLM
OT  - SIA
OT  - automation
OT  - carbaryl
OT  - carbendazim
OT  - citrus fruits
OT  - ortho-phenylphenol
OT  - pesticide
OT  - solid-phase spectroscopy
OT  - thiabendazole
EDAT- 2019/01/17 06:00
MHDA- 2019/04/13 06:00
CRDT- 2019/01/17 06:00
PHST- 2019/01/17 06:00 [pubmed]
PHST- 2019/04/13 06:00 [medline]
PHST- 2019/01/17 06:00 [entrez]
AID - 10.1080/19440049.2018.1564372 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019 
      Feb;36(2):278-288. doi: 10.1080/19440049.2018.1564372. Epub 2019 Jan 16.