PMID- 30650549
OWN - NLM
STAT- MEDLINE
DCOM- 20191227
LR  - 20231005
IS  - 2072-6651 (Electronic)
IS  - 2072-6651 (Linking)
VI  - 11
IP  - 1
DP  - 2019 Jan 15
TI  - Spatial and Temporal Variation in Paralytic Shellfish Toxin Production by Benthic 
      Microseira (Lyngbya) wollei in a Freshwater New York Lake.
LID - 10.3390/toxins11010044 [doi]
LID - 44
AB  - Butterfield Lake is a mesotrophic lake in New York State where residents and pets 
      have experienced unexplained health issues. Microseira wollei (basionym Lyngbya 
      wollei) was found at two of 15 sites in Butterfield Lake and analyzed for 
      microcystins, anatoxins, cylindrospermopsins, and paralytic shellfish poisoning 
      toxins (PSTs). Only PSTs and trace levels of anatoxin-a were detected in these 
      samples. This is the first published report of PSTs within a New York State lake. 
      To evaluate the environmental and temporal drivers leading to the observed 
      toxicity, PST content at the two sites was examined in detail. There were 
      distinct differences in the total PST content, filament nutrient, filament 
      chlorophyll, and relationship to environmental drivers between the sites, as well 
      as distinct differences in the total PST content measured using different 
      analytical techniques. A multivariate model containing site, temperature, and 
      filament chlorophyll explained 85% of the variation in PSTs observed over the 
      growing season. This work emphasizes the importance of proper site selection and 
      choice of analytical technique in the development of monitoring programs to 
      protect lake users from the occurrence of benthic cyanobacteria toxins.
FAU - Smith, Zacharias J
AU  - Smith ZJ
AD  - Department of Chemistry, State University of New York College of Environmental 
      Science and Forestry, Syracuse, NY 13210, USA. zjsmith@syr.edu.
FAU - Martin, Robbie M
AU  - Martin RM
AD  - Department of Microbiology, University of Tennessee, Knoxville, TN 37996, USA. 
      rmarti49@vols.utk.edu.
FAU - Wei, Bofan
AU  - Wei B
AD  - Department of Chemistry, State University of New York College of Environmental 
      Science and Forestry, Syracuse, NY 13210, USA. bwei101@syr.edu.
FAU - Wilhelm, Steven W
AU  - Wilhelm SW
AUID- ORCID: 0000-0001-6283-8077
AD  - Department of Microbiology, University of Tennessee, Knoxville, TN 37996, USA. 
      wilhelm@utk.edu.
FAU - Boyer, Gregory L
AU  - Boyer GL
AD  - Department of Chemistry, State University of New York College of Environmental 
      Science and Forestry, Syracuse, NY 13210, USA. glboyer@esf.edu.
LA  - eng
GR  - P01 ES028939/ES/NIEHS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20190115
PL  - Switzerland
TA  - Toxins (Basel)
JT  - Toxins
JID - 101530765
RN  - 0 (Alkaloids)
RN  - 0 (Bacterial Toxins)
RN  - 0 (Cyanobacteria Toxins)
RN  - 0 (Microcystins)
RN  - 0 (RNA, Ribosomal, 16S)
RN  - 0 (Tropanes)
RN  - 0 (Water Pollutants)
RN  - 2JIZ556BA3 (cylindrospermopsin)
RN  - 35523-89-8 (Saxitoxin)
RN  - 56HH86ZVCT (Uracil)
RN  - Microseira wollei
SB  - IM
MH  - Alkaloids
MH  - Bacterial Toxins/*analysis
MH  - Cyanobacteria/genetics/*isolation & purification
MH  - Cyanobacteria Toxins
MH  - Environmental Monitoring
MH  - Lakes/*analysis
MH  - Microcystins/*analysis
MH  - New York
MH  - RNA, Ribosomal, 16S
MH  - Saxitoxin/*analysis
MH  - Shellfish Poisoning
MH  - Tropanes/*analysis
MH  - Uracil/*analogs & derivatives/analysis
MH  - Water Pollutants/*analysis
PMC - PMC6356249
OTO - NOTNLM
OT  - Lyngbya
OT  - Microseira
OT  - freshwater cyanotoxins
OT  - paralytic shellfish poisoning toxins
COIS- The authors declare no conflicts of interest.
EDAT- 2019/01/18 06:00
MHDA- 2019/12/28 06:00
PMCR- 2019/01/01
CRDT- 2019/01/18 06:00
PHST- 2018/12/03 00:00 [received]
PHST- 2019/01/08 00:00 [revised]
PHST- 2019/01/09 00:00 [accepted]
PHST- 2019/01/18 06:00 [entrez]
PHST- 2019/01/18 06:00 [pubmed]
PHST- 2019/12/28 06:00 [medline]
PHST- 2019/01/01 00:00 [pmc-release]
AID - toxins11010044 [pii]
AID - toxins-11-00044 [pii]
AID - 10.3390/toxins11010044 [doi]
PST - epublish
SO  - Toxins (Basel). 2019 Jan 15;11(1):44. doi: 10.3390/toxins11010044.