PMID- 30658770
OWN - NLM
STAT- MEDLINE
DCOM- 20190329
LR  - 20190329
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 281
DP  - 2019 May 30
TI  - Development of precise GC-EI-MS method to determine the residual fipronil and its 
      metabolites in chicken egg.
PG  - 85-90
LID - S0308-8146(18)32145-9 [pii]
LID - 10.1016/j.foodchem.2018.12.041 [doi]
AB  - Fipronil is a highly toxic insecticide, and fipronil egg scandal greatly threaten 
      people's health. Herein, a precise and reliable method was developed for the 
      determination of fipronil and three metabolites in chicken egg by GC-EI-MS. 
      Sample pretreatment took about 20 min and baseline separation of four analytes 
      were realized within 12 min by GC-MS. Moreover, the limits of detection were 
      0.2-0.5 ng g(-1) and the limits of quantitation was 0.5-1 ng g(-1) with relative 
      standard deviations (RSDs) lower that 3.32%. Satisfactory recoveries were get in 
      the range of 81.16-103.57% for three levels of spiked samples. Finally, the 
      developed method has been applied for the analysis of egg samples from four 
      sources. Results showed that fipronil and fipronil-sulfone were detected in three 
      samples, while fipronil-desulfinyl and fipronil-sulfide were totally absent. The 
      method showed great promising in quantification of fipronil and its metabolites 
      in food safety affairs.
CI  - Copyright (c) 2018. Published by Elsevier Ltd.
FAU - Li, Xianjiang
AU  - Li X
AD  - Food Safety Laboratory, Division of Metrology in Chemistry, National Institute of 
      Metrology, Beijing 100029, China.
FAU - Li, Hongmei
AU  - Li H
AD  - Food Safety Laboratory, Division of Metrology in Chemistry, National Institute of 
      Metrology, Beijing 100029, China. Electronic address: lihm@nin.ac.cn.
FAU - Ma, Wen
AU  - Ma W
AD  - Beijing National Laboratory for Molecular Sciences, The Key Laboratory of 
      Bioorganic Chemistry and Molecular Engineering of Ministry of Education, 
      Institute of Analytical Chemistry, College of Chemistry and Molecular 
      Engineering, Peking University, Beijing 100871, China.
FAU - Guo, Zhen
AU  - Guo Z
AD  - Food Safety Laboratory, Division of Metrology in Chemistry, National Institute of 
      Metrology, Beijing 100029, China.
FAU - Li, Xiuqin
AU  - Li X
AD  - Food Safety Laboratory, Division of Metrology in Chemistry, National Institute of 
      Metrology, Beijing 100029, China.
FAU - Song, Shanjun
AU  - Song S
AD  - Food Safety Laboratory, Division of Metrology in Chemistry, National Institute of 
      Metrology, Beijing 100029, China.
FAU - Tang, Hua
AU  - Tang H
AD  - Food Safety Laboratory, Division of Metrology in Chemistry, National Institute of 
      Metrology, Beijing 100029, China.
FAU - Li, Xiaomin
AU  - Li X
AD  - Food Safety Laboratory, Division of Metrology in Chemistry, National Institute of 
      Metrology, Beijing 100029, China.
FAU - Zhang, Qinghe
AU  - Zhang Q
AD  - Food Safety Laboratory, Division of Metrology in Chemistry, National Institute of 
      Metrology, Beijing 100029, China.
LA  - eng
PT  - Journal Article
DEP - 20181217
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 0 (Acetonitriles)
RN  - 0 (Insecticides)
RN  - 0 (Pyrazoles)
RN  - 0 (Sulfones)
RN  - QGH063955F (fipronil)
RN  - Z072SB282N (acetonitrile)
SB  - IM
MH  - Acetonitriles/analysis
MH  - Eggs/*analysis
MH  - *Food Analysis
MH  - Food Contamination/*analysis
MH  - Gas Chromatography-Mass Spectrometry
MH  - Insecticides/*analysis
MH  - Limit of Detection
MH  - Pyrazoles/*analysis
MH  - Reproducibility of Results
MH  - Sulfones/analysis
OTO - NOTNLM
OT  - Fipronil
OT  - Gas chromatography tandem mass spectrometry
OT  - Liquid-liquid re-extraction
OT  - Protein precipitation
OT  - Solid-phase extraction
EDAT- 2019/01/20 06:00
MHDA- 2019/03/30 06:00
CRDT- 2019/01/20 06:00
PHST- 2018/04/28 00:00 [received]
PHST- 2018/11/22 00:00 [revised]
PHST- 2018/12/09 00:00 [accepted]
PHST- 2019/01/20 06:00 [entrez]
PHST- 2019/01/20 06:00 [pubmed]
PHST- 2019/03/30 06:00 [medline]
AID - S0308-8146(18)32145-9 [pii]
AID - 10.1016/j.foodchem.2018.12.041 [doi]
PST - ppublish
SO  - Food Chem. 2019 May 30;281:85-90. doi: 10.1016/j.foodchem.2018.12.041. Epub 2018 
      Dec 17.