PMID- 30662933
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231005
IS  - 2352-8737 (Electronic)
IS  - 2352-8737 (Linking)
VI  - 4
DP  - 2018
TI  - The Age-Well observational study on expert meditators in the Medit-Ageing 
      European project.
PG  - 756-764
LID - 10.1016/j.trci.2018.11.002 [doi]
AB  - INTRODUCTION: The Age-Well observational, cross-sectional study investigates the 
      affective and cognitive mechanisms of meditation expertise with behavioral, 
      neuroimaging, sleep, and biological measures sensitive to aging and Alzheimer's 
      disease (AD). METHODS: Thirty cognitively unimpaired individuals aged 65 years or 
      older with at least 10,000 hours of practice in mindfulness meditation (MM) and 
      loving-kindness and compassion meditation (LKCM) are selected. The outcomes are 
      the neuroimaging brain correlates of MM and LKCM and the assessments of long-term 
      meditation practices on behavioral, neural, and biological measures as compared 
      to nonmeditator older controls from the Age-Well randomized controlled trial. 
      RESULTS: Recruitment and data collection began in late 2016 and will be completed 
      by late 2019. DISCUSSION: Results are expected to foster the understanding of the 
      effects of meditation expertise on aging and of the mechanisms of action 
      underlying the meditation intervention in the Age-Well randomized controlled 
      trial. These finding will contribute to the design of meditation-based prevention 
      randomized controlled trials for the aged population and to the exploration of 
      the possible long-time developmental trajectory of meditation training.
FAU - Lutz, Antoine
AU  - Lutz A
AD  - Lyon Neuroscience Research Center INSERM U1028, CNRS UMR5292, Lyon University, 
      Lyon, France.
FAU - Klimecki, Olga M
AU  - Klimecki OM
AD  - Swiss Center for Affective Sciences, Department of Medicine and Department of 
      Psychology, University of Geneva, Geneva, Switzerland.
FAU - Collette, Fabienne
AU  - Collette F
AD  - GIGA-CRC, In Vivo Imaging, Universite de Liege, Liege, Belgium.
AD  - Belgian National Fund for Scientific Research (F.R.S.-FNRS), Bruxelles, Belgium.
FAU - Poisnel, Geraldine
AU  - Poisnel G
AD  - Universite Normandie, Inserm, Universite de Caen-Normandie, Inserm UMR-S U1237, 
      GIP Cyceron, Caen, France.
FAU - Arenaza-Urquijo, Eider
AU  - Arenaza-Urquijo E
AD  - Universite Normandie, Inserm, Universite de Caen-Normandie, Inserm UMR-S U1237, 
      GIP Cyceron, Caen, France.
FAU - Marchant, Natalie L
AU  - Marchant NL
AD  - Division of Psychiatry, University College London, London, United Kingdom.
FAU - De La Sayette, Vincent
AU  - De La Sayette V
AD  - Universite Normandie, Inserm, Universite de Caen-Normandie, Inserm UMR-S U1077, 
      GIP Cyceron, Caen, France.
AD  - CHU Caen-Normandie, Department of Clinical Research, Caen, France.
FAU - Rauchs, Geraldine
AU  - Rauchs G
AD  - Universite Normandie, Inserm, Universite de Caen-Normandie, Inserm UMR-S U1077, 
      GIP Cyceron, Caen, France.
FAU - Salmon, Eric
AU  - Salmon E
AD  - GIGA-CRC, In Vivo Imaging, Universite de Liege, Liege, Belgium.
AD  - Belgian National Fund for Scientific Research (F.R.S.-FNRS), Bruxelles, Belgium.
FAU - Vuilleumier, Patrick
AU  - Vuilleumier P
AD  - Department of Medicine, University of Geneva, Geneva, Switzerland.
FAU - Frison, Eric
AU  - Frison E
AD  - EUCLID/F-CRIN Clinical Trials Platform, University of Bordeaux, INSERM, Bordeaux 
      Population Health Center, Bordeaux, France.
AD  - CHU Bordeaux, F-33000 Bordeaux, France.
FAU - Vivien, Denis
AU  - Vivien D
AD  - Universite Normandie, Inserm, Universite de Caen-Normandie, Inserm UMR-S U1237, 
      GIP Cyceron, Caen, France.
AD  - CHU Caen-Normandie, Department of Clinical Research, Caen, France.
FAU - Chetelat, Gael
AU  - Chetelat G
AD  - Universite Normandie, Inserm, Universite de Caen-Normandie, Inserm UMR-S U1237, 
      GIP Cyceron, Caen, France.
CN  - Medit-Ageing Research Group
LA  - eng
PT  - Journal Article
DEP - 20181218
PL  - United States
TA  - Alzheimers Dement (N Y)
JT  - Alzheimer's & dementia (New York, N. Y.)
JID - 101650118
PMC - PMC6300614
OTO - NOTNLM
OT  - Aging
OT  - Alzheimer's disease
OT  - Blood markers
OT  - Cognition
OT  - Compassion and loving-kindness meditation
OT  - Dementia
OT  - Emotion
OT  - Lifestyle
OT  - Meditation expertise
OT  - Mindfulness meditation
OT  - Neuroimaging
OT  - Prevention
OT  - Reserve
OT  - Sleep
EDAT- 2019/01/22 06:00
MHDA- 2019/01/22 06:01
PMCR- 2018/12/18
CRDT- 2019/01/22 06:00
PHST- 2019/01/22 06:00 [entrez]
PHST- 2019/01/22 06:00 [pubmed]
PHST- 2019/01/22 06:01 [medline]
PHST- 2018/12/18 00:00 [pmc-release]
AID - S2352-8737(18)30077-5 [pii]
AID - 10.1016/j.trci.2018.11.002 [doi]
PST - epublish
SO  - Alzheimers Dement (N Y). 2018 Dec 18;4:756-764. doi: 10.1016/j.trci.2018.11.002. 
      eCollection 2018.