PMID- 30666637
OWN - NLM
STAT- MEDLINE
DCOM- 20190415
LR  - 20191210
IS  - 1097-0010 (Electronic)
IS  - 0022-5142 (Linking)
VI  - 99
IP  - 7
DP  - 2019 May
TI  - Method validation and simultaneous quantification of eight 
      organochlorines/organophosphates in apple by gas chromatography.
PG  - 3687-3692
LID - 10.1002/jsfa.9599 [doi]
AB  - BACKGROUND: The increasing and extensive use of pesticides worldwide has resulted 
      in a significant loss of non-target populations particularly humans by direct or 
      indirect exposures. Also, various methods have been used for the estimation of 
      pesticide residues in fruits and vegetables from recent past which are either 
      tedious, time consuming or expensive. Therefore, the present study was performed 
      to determine the pesticide residues from apple by simple and novel validated gas 
      chromatography. RESULTS: A novel, accurate, ecofriendly and cost-effective gas 
      chromatography method was developed for simultaneous quantification of eight 
      pesticides, namely chlorpyrifos-methyl (1), chlorpyrifos (2), quinolphos (3), 
      profenofos (4), myclobutnil (5), ethion (6), fenpropathrin (7) and cypermethrin 
      (8). The developed method was validated as per the SANTE guidelines. All 
      calibration curves showed a good linear relationship (r > 0.99) within the test 
      range. Precision was evaluated by intra- and inter-day tests with relative 
      standard deviations (RSDs) < 2.0%, recovery in between 70% and 120% with RSDs < 
      2.00%. CONCLUSION: The results demonstrate that the concentration of pesticides 1 
      to 8 were found below the detectable limit. Method validation parameters like 
      linearity, precision, accuracy, specificity, robustness, detection and 
      quantification limits were found within the acceptable range. The proposed method 
      makes it possible to determine simultaneously pesticides 1-8 in one run which can 
      be extended for residue-based standardization of pesticides from apple and other 
      fruits and vegetables. (c) 2019 Society of Chemical Industry.
CI  - (c) 2019 Society of Chemical Industry.
FAU - Wani, Ashraf A
AU  - Wani AA
AD  - Research Centre for Residue & Quality Analysis, Division of Entomology, 
      Sher-e-Kashmir University of Agricultural sciences & Technology of Kashmir, 
      Shalimar, Srinagar, India.
FAU - Dar, Alamgir A
AU  - Dar AA
AUID- ORCID: 0000-0003-0331-370X
AD  - Research Centre for Residue & Quality Analysis, Division of Entomology, 
      Sher-e-Kashmir University of Agricultural sciences & Technology of Kashmir, 
      Shalimar, Srinagar, India.
FAU - Jan, Ishrat
AU  - Jan I
AD  - Research Centre for Residue & Quality Analysis, Division of Entomology, 
      Sher-e-Kashmir University of Agricultural sciences & Technology of Kashmir, 
      Shalimar, Srinagar, India.
FAU - Sofi, Khurshid A
AU  - Sofi KA
AD  - Research Centre for Residue & Quality Analysis, Division of Entomology, 
      Sher-e-Kashmir University of Agricultural sciences & Technology of Kashmir, 
      Shalimar, Srinagar, India.
FAU - Sofi, Javid A
AU  - Sofi JA
AD  - Research Centre for Residue & Quality Analysis, Division of Entomology, 
      Sher-e-Kashmir University of Agricultural sciences & Technology of Kashmir, 
      Shalimar, Srinagar, India.
FAU - Dar, Irshad H
AU  - Dar IH
AD  - Research Centre for Residue & Quality Analysis, Division of Entomology, 
      Sher-e-Kashmir University of Agricultural sciences & Technology of Kashmir, 
      Shalimar, Srinagar, India.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20190227
PL  - England
TA  - J Sci Food Agric
JT  - Journal of the science of food and agriculture
JID - 0376334
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Organophosphates)
RN  - 0 (Organothiophosphates)
RN  - 0 (Pesticide Residues)
RN  - 0 (Pyrethrins)
RN  - 1TR49121NP (cypermethrin)
RN  - 7J04O7BS4W (profenofos)
RN  - 87BH96P0MX (fenpropathrin)
SB  - IM
MH  - Chromatography, Gas/*methods
MH  - Fruit/chemistry
MH  - Hydrocarbons, Chlorinated/*analysis
MH  - Limit of Detection
MH  - Malus/*chemistry
MH  - Organophosphates/*analysis
MH  - Organothiophosphates/analysis
MH  - Pesticide Residues/*analysis
MH  - Pyrethrins/analysis
OTO - NOTNLM
OT  - gas chromatography
OT  - method validation
OT  - organochlorines
OT  - organophosphates
OT  - pesticides
EDAT- 2019/01/23 06:00
MHDA- 2019/04/16 06:00
CRDT- 2019/01/23 06:00
PHST- 2018/12/28 00:00 [received]
PHST- 2019/01/14 00:00 [accepted]
PHST- 2019/01/23 06:00 [pubmed]
PHST- 2019/04/16 06:00 [medline]
PHST- 2019/01/23 06:00 [entrez]
AID - 10.1002/jsfa.9599 [doi]
PST - ppublish
SO  - J Sci Food Agric. 2019 May;99(7):3687-3692. doi: 10.1002/jsfa.9599. Epub 2019 Feb 
      27.