PMID- 30668631
OWN - NLM
STAT- MEDLINE
DCOM- 20200915
LR  - 20200915
IS  - 1532-4796 (Electronic)
IS  - 0883-6612 (Print)
IS  - 0883-6612 (Linking)
VI  - 53
IP  - 10
DP  - 2019 Aug 29
TI  - Effects of Mindfulness-Oriented Recovery Enhancement Versus Social Support on 
      Negative Affective Interference During Inhibitory Control Among Opioid-Treated 
      Chronic Pain Patients: A Pilot Mechanistic Study.
PG  - 865-876
LID - 10.1093/abm/kay096 [doi]
AB  - BACKGROUND: Among opioid-treated chronic pain patients, deficient response 
      inhibition in the context of emotional distress may contribute to maladaptive 
      pain coping and prescription opioid misuse. Interventions that aim to bolster 
      cognitive control and reduce emotional reactivity (e.g., mindfulness) may 
      remediate response inhibition deficits, with consequent clinical benefits. 
      PURPOSE: To test the hypothesis that a mindfulness-based intervention, 
      Mindfulness-Oriented Recovery Enhancement (MORE), can reduce the impact of 
      clinically relevant, negative affective interference on response inhibition 
      function in an opioid-treated chronic pain sample. METHODS: We examined data from 
      a controlled trial comparing adults with chronic pain and long-term prescription 
      opioid use randomized to either MORE (n = 27) treatment or to an active support 
      group comparison condition (n = 30). Participants completed an Emotional Go/NoGo 
      Task at pre- and post-treatment, which measured response inhibition in neutral 
      and clinically relevant, negative affective contexts (i.e., exposure to 
      pain-related visual stimuli). RESULTS: Repeated-measures analysis of variance 
      indicated that compared with the support group, participants in MORE evidenced 
      significantly greater reductions from pre- to post-treatment in errors of 
      commission on trials with pain-related distractors relative to trials with 
      neutral distractors, group x time x condition F(1,55) = 4.14, p = .047, eta2partial 
      = .07. Mindfulness practice minutes and increased nonreactivity significantly 
      predicted greater emotional response inhibition. A significant inverse 
      association was observed between improvements in emotional response inhibition 
      and treatment-related reductions in pain severity by 3-month follow-up. 
      CONCLUSIONS: Study results provide preliminary evidence that MORE enhances 
      inhibitory control function in the context of negative emotional interference.
CI  - (c) Society of Behavioral Medicine 2019. All rights reserved. For permissions, 
      please e-mail: journals.permissions@oup.com.
FAU - Garland, Eric L
AU  - Garland EL
AD  - College of Social Work, University of Utah, Salt Lake City, UT, USA.
AD  - Center on Mindfulness and Integrative Health Intervention Development, University 
      of Utah, Salt Lake City, UT, USA.
FAU - Bryan, Myranda A
AU  - Bryan MA
AD  - College of Social Work, University of Utah, Salt Lake City, UT, USA.
AD  - Center on Mindfulness and Integrative Health Intervention Development, University 
      of Utah, Salt Lake City, UT, USA.
FAU - Priddy, Sarah E
AU  - Priddy SE
AD  - College of Social Work, University of Utah, Salt Lake City, UT, USA.
AD  - Center on Mindfulness and Integrative Health Intervention Development, University 
      of Utah, Salt Lake City, UT, USA.
FAU - Riquino, Michael R
AU  - Riquino MR
AD  - College of Social Work, University of Utah, Salt Lake City, UT, USA.
AD  - Center on Mindfulness and Integrative Health Intervention Development, University 
      of Utah, Salt Lake City, UT, USA.
FAU - Froeliger, Brett
AU  - Froeliger B
AD  - Department of Neuroscience, Medical University of South Carolina, USA.
FAU - Howard, Matthew O
AU  - Howard MO
AD  - School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, 
      NC, USA.
LA  - eng
GR  - R01 DA042033/DA/NIDA NIH HHS/United States
GR  - R03 DA032517/DA/NIDA NIH HHS/United States
GR  - R61 AT009296/AT/NCCIH NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PL  - England
TA  - Ann Behav Med
JT  - Annals of behavioral medicine : a publication of the Society of Behavioral 
      Medicine
JID - 8510246
RN  - 0 (Analgesics, Opioid)
SB  - IM
MH  - Adult
MH  - Analgesics, Opioid/*therapeutic use
MH  - Chronic Pain/drug therapy/*physiopathology/*therapy
MH  - Emotions/*physiology
MH  - Executive Function/*physiology
MH  - Female
MH  - Humans
MH  - *Inhibition, Psychological
MH  - Male
MH  - Middle Aged
MH  - Mindfulness/*methods
MH  - Pilot Projects
MH  - Psychomotor Performance/*physiology
MH  - *Social Support
MH  - Treatment Outcome
PMC - PMC6735955
OTO - NOTNLM
OT  - Cognitive control
OT  - Go/NoGo
OT  - Inhibitory control
OT  - Mindfulness
OT  - Opioid
OT  - Pain
EDAT- 2019/01/23 06:00
MHDA- 2020/09/17 06:00
PMCR- 2020/01/22
CRDT- 2019/01/23 06:00
PHST- 2019/01/23 06:00 [pubmed]
PHST- 2020/09/17 06:00 [medline]
PHST- 2019/01/23 06:00 [entrez]
PHST- 2020/01/22 00:00 [pmc-release]
AID - 5298951 [pii]
AID - kay096 [pii]
AID - 10.1093/abm/kay096 [doi]
PST - ppublish
SO  - Ann Behav Med. 2019 Aug 29;53(10):865-876. doi: 10.1093/abm/kay096.