PMID- 30672196
OWN - NLM
STAT- MEDLINE
DCOM- 20190503
LR  - 20190503
IS  - 0255-2930 (Print)
IS  - 0255-2930 (Linking)
VI  - 38
IP  - 11
DP  - 2018 Nov 12
TI  - [Clinical effect and mechanism of heat sensitive moxibustion for knee joint 
      synovitis].
PG  - 1163-8
LID - 10.13703/j.0255-2930.2018.11.008 [doi]
AB  - OBJECTIVE: To observe the effect of heat sensitive moxibustion based on the 
      articular injection for knee joint synovitis. METHODS: Sixty-seven patients with 
      knee joint synovitis were randomly assigned into an observation group (34 cases) 
      and a control group (33 cases). Articular injection of triamcinolone was used in 
      the control group for 2 courses, 2 times as a course, once 5 days. Based on the 
      treatment in the control group, heat sensitive moxibustion was used in the 
      observation group for 2 courses, 2 weeks as a course, 5 times a week. The 
      acupoints were Yanglingquan (GB 34), Yinlingquan (SP 9), Liangqiu (ST 34), Xuehai 
      (SP 10), Heding (EX-LE 2) or the pain point, subcutaneous nodules around the 
      patella. American Knee Society (AKS) score was measured before and after 
      treatment and one month after treatment. At the same time, the knee joint 
      synovium thickness was measured by MRI; the knee joint effusion was observed by 
      ultrasound; the serum interleukin-1 (IL-1) and matrix metalloproteinase-3 (MMP-3) 
      were measured. RESULTS: After treatment, the AKS scores increased in the two 
      groups (both P<0.05); after treatment and at follow-up, the AKS scores in the 
      observation group were higher than those in the control group (both P<0.05); at 
      follow-up, the AKS score in the control group was lower than that after treatment 
      (P<0.05). After treatment, the synovium thickness, effusion, IL-1 and MMP-3 were 
      lower than those before treatment in the two groups (all P<0.05); after treatment 
      and at follow-up, the four indexes in the observation group were lower than those 
      in the control group (all P<0.05); at follow-up, the four indexes in the control 
      group increased than those after treatment (all P<0.05). CONCLUSION: Heat 
      sensitive moxibustion combined with medicine articular injection can improve 
      synovium inflammatory reaction and the absorption of effusion in the articular 
      cavity,with long-time effect, which are better than simple medicine articular 
      injection.
FAU - Xu, Weiming
AU  - Xu W
AD  - Department of Rehabilitation, Longhai TCM Hospital, Zhangzhou 363100, Fujian 
      Province, China.
FAU - Zhang, Guojie
AU  - Zhang G
AD  - Department of Rehabilitation, Longhai TCM Hospital, Zhangzhou 363100, Fujian 
      Province, China.
LA  - chi
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - China
TA  - Zhongguo Zhen Jiu
JT  - Zhongguo zhen jiu = Chinese acupuncture & moxibustion
JID - 8600658
SB  - IM
MH  - Acupuncture Points
MH  - Hot Temperature
MH  - Humans
MH  - Knee Joint
MH  - *Moxibustion
MH  - Osteoarthritis, Knee
MH  - *Synovitis/therapy
MH  - Treatment Outcome
OTO - NOTNLM
OT  - IL-1
OT  - MMP-3
OT  - arthrocentesis
OT  - gonarthromeningitis
OT  - heat sensitive moxibustion
OT  - hydrops articuli
EDAT- 2019/01/24 06:00
MHDA- 2019/05/06 06:00
CRDT- 2019/01/24 06:00
PHST- 2019/01/24 06:00 [entrez]
PHST- 2019/01/24 06:00 [pubmed]
PHST- 2019/05/06 06:00 [medline]
AID - 10.13703/j.0255-2930.2018.11.008 [doi]
PST - ppublish
SO  - Zhongguo Zhen Jiu. 2018 Nov 12;38(11):1163-8. doi: 
      10.13703/j.0255-2930.2018.11.008.