PMID- 30673337 OWN - NLM STAT- MEDLINE DCOM- 20191230 LR - 20191230 IS - 1546-3141 (Electronic) IS - 0361-803X (Linking) VI - 212 IP - 4 DP - 2019 Apr TI - Comparison of Tin Filter-Based Spectral Shaping CT and Low-Dose Protocol for Detection of Urinary Calculi. PG - 808-814 LID - 10.2214/AJR.18.20154 [doi] AB - OBJECTIVE: The purpose of this study was to assess the performance of tin filter-based spectral shaping CT compared with routine low-dose CT for detection of urolithiasis. MATERIALS AND METHODS: Unenhanced third-generation dual-source CT scans of 129 consecutively registered patients were retrospectively reviewed: 43 patients underwent CT for detection of renal stones with tin filtration (Sn150 kV); 43 patients underwent a routine low-dose CT protocol at 100 kV; and 43 patients underwent a routine CT protocol with automated tube potential selection (110-120 kV). Image quality was evaluated subjectively and objectively. Volume CT dose index (CTDI(vol)) and size-specific dose estimate (SSDE) were recorded. To prospectively compare the performances of the spectral shaping protocol (Sn150 kV) with the standard (120 kV) and routine low-dose (100 kV) protocols, a phantom (sheep kidneys) containing stones were also scanned with each protocol and evaluated by two radiologists. RESULTS: CT with tin filtration resulted in 28% and 66% reduction in CTDI(vol) compared with CT performed with routine low-dose and standard-dose protocols (p < 0.05). Accordingly, it also led to 24% and 55% reduction in SSDE compared with the low-dose and standard protocols (p < 0.05). Subjective image quality and signal-to-noise ratio were similar between the tin filtration and the routine low-dose groups (p > 0.05). The objective image noise was similar in the three groups (p > 0.05). The phantom study showed no difference in detection of renal stones between the three tube potential settings. CONCLUSION: Using spectral shaping with tin filtration can substantially reduce radiation dose compared with routine standard- and low-dose abdominal CT for urinary stone disease. FAU - Mozaffary, Amirhossein AU - Mozaffary A AD - 1 Department of Radiology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Ste 800, Chicago, IL 60611. FAU - Trabzonlu, Tugce Agirlar AU - Trabzonlu TA AD - 1 Department of Radiology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Ste 800, Chicago, IL 60611. FAU - Kim, Donald AU - Kim D AD - 1 Department of Radiology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Ste 800, Chicago, IL 60611. FAU - Yaghmai, Vahid AU - Yaghmai V AD - 1 Department of Radiology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Ste 800, Chicago, IL 60611. LA - eng PT - Comparative Study PT - Journal Article DEP - 20190123 PL - United States TA - AJR Am J Roentgenol JT - AJR. American journal of roentgenology JID - 7708173 RN - 7440-31-5 (Tin) SB - IM MH - Adult MH - Aged MH - Animals MH - Female MH - Humans MH - Male MH - Middle Aged MH - Phantoms, Imaging MH - Radiation Dosage MH - Radiation Protection/methods MH - Retrospective Studies MH - Sheep MH - Tin MH - Tomography, X-Ray Computed/*methods MH - Urinary Calculi/*diagnostic imaging OTO - NOTNLM OT - CT OT - dose reduction OT - image quality OT - kidney stone OT - spectral shielding OT - tin filtration EDAT- 2019/01/24 06:00 MHDA- 2019/12/31 06:00 CRDT- 2019/01/24 06:00 PHST- 2019/01/24 06:00 [pubmed] PHST- 2019/12/31 06:00 [medline] PHST- 2019/01/24 06:00 [entrez] AID - 10.2214/AJR.18.20154 [doi] PST - ppublish SO - AJR Am J Roentgenol. 2019 Apr;212(4):808-814. doi: 10.2214/AJR.18.20154. Epub 2019 Jan 23.