PMID- 30675966
OWN - NLM
STAT- MEDLINE
DCOM- 20190619
LR  - 20190619
IS  - 1479-8301 (Electronic)
IS  - 1346-3500 (Linking)
VI  - 19
IP  - 3
DP  - 2019 May
TI  - Factors influencing hospital admission among patients with autopsy-confirmed 
      dementia.
PG  - 255-263
LID - 10.1111/psyg.12393 [doi]
AB  - BACKGROUND: The symptoms of geriatric syndromes and the behavioural and 
      psychological symptoms of dementia (BPSD), in addition to clinical conditions, 
      are associated with hospital admission among dementia patients. However, the 
      principal factors that necessitate hospital admission among dementia patients 
      have not been fully elucidated. METHODS: We retrospectively reviewed the data in 
      the medical and autopsy reports of patients who had been treated at a hospital in 
      Toyohashi, Japan. Each patient had been hospitalized sometime between 2012 and 
      2016 and underwent a brain autopsy. Dementia and the subtypes of dementia were 
      diagnosed neuropathologically. Information about patients' general backgrounds, 
      clinical conditions at the time of admission, and the geriatric syndrome symptoms 
      and BPSD before admission was collected; comparisons were then made between 
      patients with and without dementia and among those with the different major 
      subtypes of dementia. Then, the factors relating to hospital admission of 
      dementia patients were comprehensively evaluated by using principle component 
      analysis. RESULTS: Of the 128 eligible patients, 100 (78.1%) had dementia. In the 
      comparison of patients with and without dementia, patients without dementia were 
      younger at both admission (P = 0.034) and death (P = 0.003). Among the patients 
      with dementia with Lewy bodies, delusions had a significantly high prevalence 
      (P = 0.014). Principal component analysis identified nine components 
      (disinhibition, irritability/lability, agitation/aggression, anxiety, delusions, 
      sleep/night-time behaviour disorders, hallucinations, aberrant motor behaviour, 
      and speech impairment) as the principal factors related to hospital admission 
      among dementia patients. Thus, BPSD were identified as principal factors. 
      CONCLUSIONS: Compared to other factors, BPSD are more likely to cause dementia 
      patients to be admitted to hospital. The present results indicate that measures 
      should be taken to ameliorate the difficulties associated with caring for 
      patients with BPSD at home.
CI  - (c) 2019 Japanese Psychogeriatric Society.
FAU - Matsuoka, Tamami
AU  - Matsuoka T
AD  - Department of Social Health and Stress Management, University of Tsukuba, 
      Graduate School of Comprehensive Human Science, Tsukuba, Japan.
FAU - Manabe, Toshie
AU  - Manabe T
AD  - Department of Social Health and Stress Management, University of Tsukuba, 
      Graduate School of Comprehensive Human Science, Tsukuba, Japan.
AD  - Department of Hygiene and Public Health, Teikyo University School of Medicine, 
      Tokyo, Japan.
AD  - Department of Community-based Medicine, Nagoya City University Graduate School of 
      Medicine, Nagoya, Japan.
FAU - Akatsu, Hiroyasu
AU  - Akatsu H
AD  - Department of Community-based Medicine, Nagoya City University Graduate School of 
      Medicine, Nagoya, Japan.
AD  - Fukushimura Hospital, Toyohashi, Japan.
FAU - Hashizume, Yoshio
AU  - Hashizume Y
AD  - Fukushimura Hospital, Toyohashi, Japan.
FAU - Yamamoto, Sakon
AU  - Yamamoto S
AD  - Fukushimura Hospital, Toyohashi, Japan.
FAU - Ogawa, Norihiro
AU  - Ogawa N
AD  - Fukushimura Hospital, Toyohashi, Japan.
FAU - Kanesaka, Takeshi
AU  - Kanesaka T
AD  - Fukushimura Hospital, Toyohashi, Japan.
FAU - Taniguchi, Chie
AU  - Taniguchi C
AD  - Fukushimura Hospital, Toyohashi, Japan.
FAU - Yamamoto, Takayuki
AU  - Yamamoto T
AD  - Fukushimura Hospital, Toyohashi, Japan.
FAU - Mizukami, Katsuyoshi
AU  - Mizukami K
AUID- ORCID: 0000-0001-9903-7310
AD  - Department of Social Health and Stress Management, University of Tsukuba, 
      Graduate School of Comprehensive Human Science, Tsukuba, Japan.
AD  - Faculty of Health and Sport Sciences, University of Tsukuba, Tokyo, Japan.
LA  - eng
PT  - Journal Article
DEP - 20190124
PL  - England
TA  - Psychogeriatrics
JT  - Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society
JID - 101230058
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Anxiety/diagnosis/*epidemiology/psychology
MH  - Autopsy
MH  - Behavioral Symptoms/*epidemiology/psychology
MH  - Brain/pathology
MH  - Delusions/*epidemiology/psychology
MH  - Dementia/*diagnosis/pathology/psychology
MH  - Female
MH  - Hospitalization/*statistics & numerical data
MH  - Humans
MH  - Inpatients/psychology/*statistics & numerical data
MH  - Irritable Mood
MH  - Japan/epidemiology
MH  - Neuropsychological Tests
MH  - Prevalence
MH  - Principal Component Analysis
MH  - Psychomotor Agitation/*epidemiology/psychology
MH  - Retrospective Studies
MH  - Social Behavior Disorders/*epidemiology/psychology
OTO - NOTNLM
OT  - behavioural and psychological symptoms of dementia
OT  - cause of hospital admission
OT  - dementia
OT  - geriatric syndrome
OT  - principle component analysis
EDAT- 2019/01/25 06:00
MHDA- 2019/06/20 06:00
CRDT- 2019/01/25 06:00
PHST- 2018/05/23 00:00 [received]
PHST- 2018/10/07 00:00 [revised]
PHST- 2018/11/21 00:00 [accepted]
PHST- 2019/01/25 06:00 [pubmed]
PHST- 2019/06/20 06:00 [medline]
PHST- 2019/01/25 06:00 [entrez]
AID - 10.1111/psyg.12393 [doi]
PST - ppublish
SO  - Psychogeriatrics. 2019 May;19(3):255-263. doi: 10.1111/psyg.12393. Epub 2019 Jan 
      24.