PMID- 30677968
OWN - NLM
STAT- MEDLINE
DCOM- 20190226
LR  - 20190226
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 658
DP  - 2019 Mar 25
TI  - Bioaccumulation behavior and spatiotemporal trends of per- and polyfluoroalkyl 
      substances in Indo-Pacific humpback dolphins from the Pearl River Estuary, China.
PG  - 1029-1038
LID - S0048-9697(18)35151-9 [pii]
LID - 10.1016/j.scitotenv.2018.12.278 [doi]
AB  - Sixteen per- and polyfluoroalkyl substances (PFASs) were measured in liver 
      (n = 52) and kidney (n = 18) tissues of Indo-Pacific humpback dolphins (Sousa 
      chinensis) stranded in the Pearl River Estuary (PRE) of China between 2004 and 
      2016. The average concentrations of perfluorooctane sulfonate (PFOS), 
      perfluorooctanoic acid (PFOA) and most of other PFASs in the liver samples were 
      respectively greater than any records previously reported in cetaceans globally. 
      PFOS levels in 46% of dolphin liver samples exceeded the hepatic toxicity 
      threshold in cetaceans. For the first time, we found a U-shaped trend for the 
      distribution pattern of perfluorinated carboxylic acids (PFCAs) between liver and 
      kidney with increasing carbon chain lengths (C5-C16), whereas a descending trend 
      (C4-C10) was found for perfluoroalkane sulfonic acids (PFASs), which may be 
      explained by binding efficiencies of PFAS analogues to proteins. Dolphins with 
      the highest levels of  summation operatorPFASs (age-corrected) were clustered near the river 
      outlets in Lingdingyang area, which agrees with the spatial distribution of PFASs 
      in the environment. Significant temporal trends were observed for many PFASs. 
      Concentrations of PFOA, perfluorononanoic acid (PFNA), perfluorodecanoic acid 
      (PFDA) and perfluoroheptanoic acid (PFHpA) all peaked in year 2011, followed by a 
      decreasing trend, while a consistently descending trend was shown for 
      perfluoroundecanoic acid (PFUdA) and perfluorodecane sulfonate (PFDS). Our 
      findings contribute to the knowledge of tissue distribution and spatiotemporal 
      trends of PFASs in the PRE dolphins, which are valuable for us to understand the 
      PFASs exposure risk and their industrial emission in Southern China.
CI  - Copyright (c) 2018. Published by Elsevier B.V.
FAU - Gui, Duan
AU  - Gui D
AD  - Zhuhai Key Laboratory of Marine Bioresources and Environment, Guangdong 
      Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of 
      Marine Sciences, Sun Yat-Sen University, Zhuhai 519000, China.
FAU - Zhang, Mei
AU  - Zhang M
AD  - Zhuhai Key Laboratory of Marine Bioresources and Environment, Guangdong 
      Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of 
      Marine Sciences, Sun Yat-Sen University, Zhuhai 519000, China.
FAU - Zhang, Tao
AU  - Zhang T
AD  - School of Environmental Science and Engineering, Sun Yat-Sen University, 
      Guangzhou 510275, China; Guangdong Provincial Key Laboratory of Environmental 
      Pollution Control and Remediation Technology, Sun Yat-Sen University, Guangzhou 
      510275, China. Electronic address: zhangt47@mail.sysu.edu.cn.
FAU - Zhang, Bo
AU  - Zhang B
AD  - School of Environmental Science and Engineering, Sun Yat-Sen University, 
      Guangzhou 510275, China; Guangdong Provincial Key Laboratory of Environmental 
      Pollution Control and Remediation Technology, Sun Yat-Sen University, Guangzhou 
      510275, China.
FAU - Lin, Wenzhi
AU  - Lin W
AD  - Zhuhai Key Laboratory of Marine Bioresources and Environment, Guangdong 
      Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of 
      Marine Sciences, Sun Yat-Sen University, Zhuhai 519000, China.
FAU - Sun, Xian
AU  - Sun X
AD  - Zhuhai Key Laboratory of Marine Bioresources and Environment, Guangdong 
      Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of 
      Marine Sciences, Sun Yat-Sen University, Zhuhai 519000, China.
FAU - Yu, Xinjian
AU  - Yu X
AD  - Zhuhai Key Laboratory of Marine Bioresources and Environment, Guangdong 
      Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of 
      Marine Sciences, Sun Yat-Sen University, Zhuhai 519000, China.
FAU - Liu, Wen
AU  - Liu W
AD  - Zhuhai Key Laboratory of Marine Bioresources and Environment, Guangdong 
      Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of 
      Marine Sciences, Sun Yat-Sen University, Zhuhai 519000, China.
FAU - Wu, Yuping
AU  - Wu Y
AD  - Zhuhai Key Laboratory of Marine Bioresources and Environment, Guangdong 
      Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of 
      Marine Sciences, Sun Yat-Sen University, Zhuhai 519000, China. Electronic 
      address: exwyp@mail.sysu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20181219
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Fluorocarbons)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Animals
MH  - China
MH  - Dolphins/*metabolism
MH  - *Environmental Exposure
MH  - Environmental Monitoring
MH  - Estuaries
MH  - Fluorocarbons/*metabolism
MH  - Spatio-Temporal Analysis
MH  - Water Pollutants, Chemical/*metabolism
OTO - NOTNLM
OT  - Cetaceans
OT  - Indo-Pacific humpback dolphins
OT  - Per- and Polyfluoroalkyl substances
OT  - Spatiotemporal trends
EDAT- 2019/01/27 06:00
MHDA- 2019/02/27 06:00
CRDT- 2019/01/26 06:00
PHST- 2018/07/20 00:00 [received]
PHST- 2018/12/18 00:00 [revised]
PHST- 2018/12/18 00:00 [accepted]
PHST- 2019/01/26 06:00 [entrez]
PHST- 2019/01/27 06:00 [pubmed]
PHST- 2019/02/27 06:00 [medline]
AID - S0048-9697(18)35151-9 [pii]
AID - 10.1016/j.scitotenv.2018.12.278 [doi]
PST - ppublish
SO  - Sci Total Environ. 2019 Mar 25;658:1029-1038. doi: 
      10.1016/j.scitotenv.2018.12.278. Epub 2018 Dec 19.