PMID- 30678356
OWN - NLM
STAT- MEDLINE
DCOM- 20190423
LR  - 20200225
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 24
IP  - 3
DP  - 2019 Jan 24
TI  - Determination of Selected Priority Pesticides in High Water Fruits and Vegetables 
      by Modified QuEChERS and GC-ECD with GC-MS/MS Confirmation.
LID - 10.3390/molecules24030417 [doi]
LID - 417
AB  - A modified quick, easy, cheap, efficient, rugged and safe (QuEChERS) method 
      coupled to gas chromatography with electron capture detector (GC-ECD) was 
      developed for simultaneous determination of selected electronegative pesticides 
      in fruits and vegetables with high water content. The chosen compounds are 
      commonly detected in fruit and vegetable crops, and some of their metabolites 
      have even been found in human urine. In addition, some of them are known or 
      suspected carcinogens according to the International Agency for Research of 
      Cancer. Extraction and clean up parameters were optimized, thus the original 
      QuEChERS method was modified to decrease solvent usage, in accordance with 'green 
      chemistry' principles. The proposed methodology was validated in terms of 
      selectivity, specificity, linearity, precision and accuracy. The obtained limits 
      of detection (LODs) for all investigated pesticides ranged from 5.6 microg.kg(-1) to 
      15 microg.kg(-1) and limits of quantification (LOQs) from 17 microg.kg(-1) to 45 
      microg.kg(-1). The obtained data demonstrated the good reproducibility and stability 
      of the procedure in the tested concentration range up to 10 mg.kg(-1), with 
      relative standard deviations (RSDs) lower than 10%. Recoveries for spiked pear 
      samples at LOQ level for each pesticide were from 90% to 107% with RSDs lower 
      than 9.6%. The suitability of the developed procedure was tested on various fruit 
      and vegetable samples available on the market at different seasons. The proposed 
      methodology is applicable for detection and monitoring of selected pesticides not 
      only in fruits and vegetables with high water content, but also in samples 
      containing large amounts of pigments and dyes.
FAU - Tankiewicz, Maciej
AU  - Tankiewicz M
AUID- ORCID: 0000-0002-0966-7763
AD  - Department of Environmental Toxicology, Faculty of Health Sciences with 
      Subfaculty of Nursing and Institute of Maritime and Tropical Medicine, Medical 
      University of Gdansk, Debowa Str. 23A, 80-204 Gdansk, Poland. 
      maciej.tankiewicz@gumed.edu.pl.
LA  - eng
GR  - 2015/19/D/NZ7/03283/Narodowe Centrum Nauki/
PT  - Journal Article
DEP - 20190124
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - 0 (Pesticide Residues)
RN  - 0 (Pesticides)
SB  - IM
MH  - Food Analysis/*methods
MH  - *Fruit
MH  - *Gas Chromatography-Mass Spectrometry
MH  - Pesticide Residues/*analysis
MH  - Pesticides/*analysis
MH  - Sensitivity and Specificity
MH  - *Tandem Mass Spectrometry
MH  - *Vegetables
PMC - PMC6384567
OTO - NOTNLM
OT  - QuEChERS method
OT  - fruits and vegetables
OT  - gas chromatography
OT  - pesticides
COIS- The author declares no conflict of interest.
EDAT- 2019/01/27 06:00
MHDA- 2019/04/24 06:00
PMCR- 2019/01/24
CRDT- 2019/01/26 06:00
PHST- 2018/12/21 00:00 [received]
PHST- 2019/01/10 00:00 [revised]
PHST- 2019/01/23 00:00 [accepted]
PHST- 2019/01/26 06:00 [entrez]
PHST- 2019/01/27 06:00 [pubmed]
PHST- 2019/04/24 06:00 [medline]
PHST- 2019/01/24 00:00 [pmc-release]
AID - molecules24030417 [pii]
AID - molecules-24-00417 [pii]
AID - 10.3390/molecules24030417 [doi]
PST - epublish
SO  - Molecules. 2019 Jan 24;24(3):417. doi: 10.3390/molecules24030417.