PMID- 30679091
OWN - NLM
STAT- MEDLINE
DCOM- 20210505
LR  - 20210505
IS  - 1545-004X (Electronic)
IS  - 0894-1130 (Linking)
VI  - 33
IP  - 1
DP  - 2020 Jan-Mar
TI  - Pressure algometry and palpation of the upper limb peripheral nervous system in 
      subjects with hand osteoarthritis are repeatable and suggest central changes.
PG  - 103-111
LID - S0894-1130(17)30424-6 [pii]
LID - 10.1016/j.jht.2018.06.003 [doi]
AB  - STUDY DESIGN: Case-control study. INTRODUCTION: A subset of patients with hand 
      osteoarthritis (OA) shows evidence of central pain phenotypes. PURPOSE OF THE 
      STUDY: To examine whether differences exist in experimental pain responses in the 
      affected and nonaffected sides of patients with unilateral hand OA. To 
      investigate the test-retest reliability of pressure algometry and manual digital 
      palpation in patients with unilateral hand OA. METHODS: The hand OA group 
      consisted of 20 patients, and the control group consisted of 20 healthy subjects. 
      Pressure pain threshold (PPT) measurements were made 2 times, consisting of 3 
      repeat trials, each using computerized algometry and manual digital palpation. 
      Grip and key strength (dynamometer), pain (visual analog scale), and function 
      (Disabilities of the Arm, Shoulder and Hand [short version]) were also measured. 
      The 2-way analysis of variance was conducted to determine the differences between 
      sides and groups. Intraclass correlation coefficient (ICC) and standard error of 
      measurement were calculated. RESULTS: Patients with hand OA had decreased PPTs 
      over the thumb carpometacarpal joint as well as radial and median nerves compared 
      with controls (all P < .01). No significant group effect by side interaction was 
      detected for any measure. The minimal detectable change values needed to detect 
      change in subjects with hand OA were C5-C6 joint (0.3-0.5 kg/cm(2)), 
      carpometacarpal joint (0.3-0.5 kg/cm(2)), hamate bone (0.2-0.4 kg/cm(2)), radial 
      nerve (0.2-0.8 kg/cm(2)), median nerve (0.3-0.6 kg/cm(2)), and ulnar nerve 
      (0.2-0.4 kg/cm(2)) for PPT. Test-retest reliability was calculated for both hands 
      of participants with OA (ICC, 0.98-0.99) and healthy participants (ICC, 
      0.74-0.99). DISCUSSION: Although pressure algometry and manual digital palpation 
      are techniques already used in previous studies and have been shown to be 
      reproducible and moderately reliable for joint palpation, this current study 
      suggests that pressure algometry and manual digital palpation could also be 
      reliable methods of determining nerve sensitivity of the radial, ulnar and median 
      nerves in subjects with hand OA. CONCLUSIONS: Hyperalgesia in patients with hand 
      OA might be associated with clinical measures, and bilateral signs in unilateral 
      OA could suggest central changes.
CI  - Copyright (c) 2018 Hanley & Belfus. Published by Elsevier Inc. All rights reserved.
FAU - Pedersini, Paolo
AU  - Pedersini P
AD  - IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
FAU - Negrini, Stefano
AU  - Negrini S
AD  - IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy; Department of Clinical and 
      Experimental Sciences, University of Brescia, Brescia, Italy.
FAU - Cantero-Tellez, Raquel
AU  - Cantero-Tellez R
AD  - Physical Therapy Section, Faculty of Health Sciences, University of Malaga, Tecan 
      Hand Center, Malaga, Spain.
FAU - Bishop, Mark D
AU  - Bishop MD
AD  - Department of Physical Therapy, University of Florida, Gainesville, FL, USA.
FAU - Villafane, Jorge Hugo
AU  - Villafane JH
AD  - IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy. Electronic address: 
      mail@villafane.it.
LA  - eng
PT  - Journal Article
DEP - 20190121
PL  - United States
TA  - J Hand Ther
JT  - Journal of hand therapy : official journal of the American Society of Hand 
      Therapists
JID - 8806591
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Brachial Plexus/*physiopathology
MH  - Case-Control Studies
MH  - Female
MH  - Hand Joints/*innervation
MH  - Hand Strength
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Osteoarthritis/*diagnosis/*physiopathology
MH  - Pain Measurement
MH  - Palpation
MH  - Range of Motion, Articular
MH  - Reproducibility of Results
MH  - Upper Extremity/*innervation/physiopathology
OTO - NOTNLM
OT  - Hand
OT  - Hypersensitivity
OT  - Osteoarthritis
OT  - Pain
EDAT- 2019/01/27 06:00
MHDA- 2021/05/06 06:00
CRDT- 2019/01/26 06:00
PHST- 2017/12/19 00:00 [received]
PHST- 2018/06/20 00:00 [revised]
PHST- 2018/06/20 00:00 [accepted]
PHST- 2019/01/27 06:00 [pubmed]
PHST- 2021/05/06 06:00 [medline]
PHST- 2019/01/26 06:00 [entrez]
AID - S0894-1130(17)30424-6 [pii]
AID - 10.1016/j.jht.2018.06.003 [doi]
PST - ppublish
SO  - J Hand Ther. 2020 Jan-Mar;33(1):103-111. doi: 10.1016/j.jht.2018.06.003. Epub 
      2019 Jan 21.