PMID- 30681001
OWN - NLM
STAT- MEDLINE
DCOM- 20200706
LR  - 20200706
IS  - 2042-6313 (Electronic)
IS  - 2042-6305 (Linking)
VI  - 8
IP  - 5
DP  - 2019 Apr
TI  - Using flowable gelatin in anterior cervical spine surgery in real-world practice: 
      a retrospective cohort study.
PG  - 317-326
LID - 10.2217/cer-2018-0121 [doi]
AB  - AIM: To assess the clinical and economic impact of flowable gelatin hemostatic 
      matrix (FGHM) in anterior cervical spine surgery (ACSS). PATIENTS & METHODS: A 
      total of 451 patients with performed ACSS were included to compare FGHM with 
      conventional hemostatic methods for clinical and cost outcomes using propensity 
      score matching method. RESULTS: The comparisons of the matched 125 pairs observed 
      that FGHM was associated with significantly lower blood transfusion volume (11.2 
      vs 36.3 ml; p = 0.039), shorter postsurgery hospital stay length (3.7 vs 4.7 
      days; p = 0.002), shorter operation time (103.5 vs 117.7 min; p = 0.004), lower 
      drainage placement rate (51.2 vs 89.6%; p < 0.001) and also lower total hospital 
      costs (median  yen64,717 vs  yen65,064; p = 0.035). CONCLUSION: Use of FGHM in ACSS 
      improved perioperative outcomes without increasing hospital costs.
FAU - Wu, Yunchang
AU  - Wu Y
AD  - Department of Orthopedics, Chinese PLA General Hospital, Beijing, China.
FAU - Wu, Yiqing
AU  - Wu Y
AD  - Health Economics, Johnson & Johnson Medical China, Shanghai, China.
FAU - Gangoli, Gaurav
AU  - Gangoli G
AD  - Health Economics & Market Access, Johnson & Johnson Medical Devices Companies, 
      Somerville, NJ, USA.
FAU - Bourcet, Anh
AU  - Bourcet A
AD  - Health Economics, Johnson & Johnson Medical Asia-Pacific, Singapore.
FAU - Danker, Walter 3rd
AU  - Danker W 3rd
AD  - Health Economics & Market Access, Johnson & Johnson Medical Devices Companies, 
      Somerville, NJ, USA.
FAU - Gong, Qianyi
AU  - Gong Q
AD  - Health Economics and Outcomes Research, Changsha Normin Health Technology Ltd, 
      Changsha, Hunan, China.
FAU - Zhan, Huan
AU  - Zhan H
AD  - Health Economics and Outcomes Research, Changsha Normin Health Technology Ltd, 
      Changsha, Hunan, China.
FAU - Chen, Wendong
AU  - Chen W
AD  - Health Economics and Outcomes Research, Changsha Normin Health Technology Ltd, 
      Changsha, Hunan, China.
AD  - Health Economics and Outcomes Research, Normin Health Consulting Ltd, Toronto, 
      Ontario, Canada.
FAU - Wang, Zheng
AU  - Wang Z
AD  - Department of Orthopedics, Chinese PLA General Hospital, Beijing, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190125
PL  - England
TA  - J Comp Eff Res
JT  - Journal of comparative effectiveness research
JID - 101577308
RN  - 0 (Hemostatics)
RN  - 9000-70-8 (Gelatin)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Transfusion/statistics & numerical data
MH  - Cervical Vertebrae/*surgery
MH  - Diskectomy/*methods
MH  - Female
MH  - Gelatin/economics/*therapeutic use
MH  - Hemostatics/*therapeutic use
MH  - Hospital Costs
MH  - Humans
MH  - Length of Stay/statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - Models, Economic
MH  - Operative Time
MH  - Propensity Score
MH  - Retrospective Studies
MH  - Spinal Fusion/*methods
OTO - NOTNLM
OT  - anterior cervical spine surgery
OT  - flowable gelatin hemostatic matrix
OT  - hemostasis
OT  - hospital costs
OT  - propensity scored matching
EDAT- 2019/01/27 06:00
MHDA- 2020/07/07 06:00
CRDT- 2019/01/26 06:00
PHST- 2019/01/27 06:00 [pubmed]
PHST- 2020/07/07 06:00 [medline]
PHST- 2019/01/26 06:00 [entrez]
AID - 10.2217/cer-2018-0121 [doi]
PST - ppublish
SO  - J Comp Eff Res. 2019 Apr;8(5):317-326. doi: 10.2217/cer-2018-0121. Epub 2019 Jan 
      25.